Degron Pathways and Leishmaniasis: Debating Potential Roles of Leishmania spp. Proteases Activity on Guiding Hosts Immune Response and Their Relevance to the Development of Vaccine...

por Oliveira, Adriane Silva, Aredes-Riguetti, Lara Mata, Pereira, Bernardo Acácio Santini, Alves, Carlos Roberto, Souza-Silva, Franklin
Publicado 2023

Overview of the organization of protease genes in the genome of Leishmania spp

por Silva-Almeida, Mariana, Souza-Silva, Franklin, Pereira, Bernardo Acácio Santini, Ribeiro-Guimarães, Michelle Lopes, Alves, Carlos Roberto
Publicado 2014

Epoxy-α-lapachone (2,2-Dimethyl-3,4-dihydro-spiro[2H-naphtho[2,3-b]pyran-10,2′-oxirane]-5(10H)-one): a promising molecule to control infections caused by protozoan parasites

por Peixoto, Juliana Figueiredo, Oliveira, Adriane da Silva, Gonçalves - Oliveira, Luiz Filipe, Souza - Silva, Franklin, Alves, Carlos Roberto
Publicado 2023

Detection of Antibodies against Hepatitis A Virus (HAV) by a Surface Plasmon Resonance (SPR) Biosensor: A New Diagnosis Tool Based on the Major HAV Capsid Protein VP1 (SPR-HAVP1)

por dos Santos, Gabriel Menezes Costa, Alves, Carlos Roberto, Pinto, Marcelo Alves, Amado Leon, Luciane Almeida, Souza-Silva, Franklin
Publicado 2021

Combining Well-Tempered Metadynamics Simulation and SPR Assays to Characterize the Binding Mechanism of the Universal T-Lymphocyte Tetanus Toxin Epitope TT830-843

por Brandt, Artur A. M. L., Rodrigues-da-Silva, Rodrigo N., Lima-Junior, Josué C., Alves, Carlos R., de Souza-Silva, Franklin
Publicado 2021

Exploring the Association of Surface Plasmon Resonance with Recombinant MHC:Ig Hybrid Protein as a Tool for Detecting T Lymphocytes in Mice Infected with Leishmania (Leishmania) am...

por da Silveira-Júnior, Lenilton Silva, Souza-Silva, Franklin, Pereira, Bernardo Acácio Santini, Cysne-Finkelstein, Léa, Cavalcanti Júnior, Geraldo Barroso, Alves, Carlos Roberto
Publicado 2017

Serine Proteinases in Leishmania (Viannia) braziliensis Promastigotes Have Distinct Subcellular Distributions and Expression

por Santos-de-Souza, Raquel, Monteiro de Castro Côrtes, Luzia, dos Santos Charret, Karen, Cysne-Finkelstein, Léa, Alves, Carlos Roberto, Souza-Silva, Franklin
Publicado 2019

In Silico Insights into the Mechanism of Action of Epoxy-α-Lapachone and Epoxymethyl-Lawsone in Leishmania spp.

por Peixoto, Juliana Figueiredo, Oliveira, Adriane da Silva, Monteiro, Patrícia Queiroz, Gonçalves-Oliveira, Luiz Filipe, Andrade-Neto, Valter Viana, Ferreira, Vitor Francisco, Souza-Silva, Franklin, Alves, Carlos Roberto
Publicado 2021

Reactivity of sera from dogs living in a leishmaniasis-endemic area to the COOH-terminal region of cysteine proteinase B

por Barral-Veloso, Laura, Melo, Barbara Cristina de Albuquerque, Santos-de-Souza, Raquel, Cysne-Finkelstein, Léa, Souza-Silva, Franklin, Santos, Fernanda Nunes, Sousa, Joel Fontes de, Alves, Carlos Roberto
Publicado 2020

Novel Insights Into Leishmania (Viannia) braziliensis In Vitro Fitness Guided by Temperature Changes Along With Its Subtilisins and Oligopeptidase B

por Zabala-Peñafiel, Anabel, Cysne-Finkelstein, Lea, Conceição-Silva, Fatima, Fagundes, Aline, Miranda, Luciana de Freitas Campos, Souza-Silva, Franklin, Brandt, Artur A. M. L., Dias-Lopes, Geovane, Alves, Carlos Roberto
Publicado 2022

Evidence for Tissue Toxicity in BALB/c Exposed to a Long-Term Treatment with Oxiranes Compared to Meglumine Antimoniate

por Oliveira, Luiz Filipe Gonçalves, Souza-Silva, Franklin, Cysne-Finkelstein, Léa, Rabelo, Kíssila, Amorim, Juliana Fernandes, Azevedo, Adriana de Souza, Bourguignon, Saulo Cabral, Ferreira, Vitor Francisco, Paes, Marciano Viana, Alves, Carlos Roberto
Publicado 2017

Serine proteases profiles of Leishmania (Viannia) braziliensis clinical isolates with distinct susceptibilities to antimony

por Zabala-Peñafiel, Anabel, Dias-Lopes, Geovane, Cysne-Finkelstein, Léa, Conceição-Silva, Fátima, Miranda, Luciana de Freitas Campos, Fagundes, Aline, Schubach, Armando de Oliveira, Fernandes Pimentel, Maria Inês, Souza-Silva, Franklin, Machado, Lucas de Almeida, Alves, Carlos Roberto
Publicado 2021

Antileishmanial Activity of 2-Methoxy-4H-spiro-[naphthalene-1,2′-oxiran]-4-one (Epoxymethoxy-lawsone): A Promising New Drug Candidate for Leishmaniasis Treatment

por Oliveira, Luiz Filipe Gonçalves, Souza-Silva, Franklin, de Castro Côrtes, Luzia Monteiro, Cysne-Finkelstein, Lea, de Souza Pereira, Mirian Cláudia, de Oliveira Junior, Francisco Odêncio, Pinho, Rosa Teixeira, Corte Real, Suzana, Bourguignon, Saulo Cabral, Ferreira, Vitor Francisco, Alves, Carlos Roberto
Publicado 2018

The combination therapy of meglumine antimoniate and oxiranes (epoxy-α-lapachone and epoxymethyl-lawsone) enhance the leishmanicidal effect in mice infected by Leishmania (Leishman...

por Gonçalves-Oliveira, Luiz Filipe, Souza-Silva, Franklin, de Castro Côrtes, Luzia Monteiro, Veloso, Laura Barral, Santini Pereira, Bernardo Acácio, Cysne-Finkelstein, Lea, Lechuga, Guilherme Curty, Bourguignon, Saulo Cabral, Almeida-Souza, Fernando, da Silva Calabrese, Kátia, Ferreira, Vitor Francisco, Alves, Carlos Roberto
Publicado 2019

SARS-CoV-2 Proteins Bind to Hemoglobin and Its Metabolites

por Lechuga, Guilherme C., Souza-Silva, Franklin, Sacramento, Carolina Q., Trugilho, Monique R. O., Valente, Richard H., Napoleão-Pêgo, Paloma, Dias, Suelen S. G., Fintelman-Rodrigues, Natalia, Temerozo, Jairo R., Carels, Nicolas, Alves, Carlos R., Pereira, Mirian C. S., Provance, David W., Souza, Thiago M. L., De-Simone, Salvatore G.
Publicado 2021