Networking the Leishmania research community for the development of novel anti-leishmanial intervention strategies

por Späth, Gerald F
Publicado 2011

GIP: an open-source computational pipeline for mapping genomic instability from protists to cancer cells

por Späth, Gerald F, Bussotti, Giovanni
Publicado 2021

Hepatocyte Nuclear Factor 4 Provokes Expression of Epithelial Marker Genes, Acting As a Morphogen in Dedifferentiated Hepatoma Cells

por Späth, Gerald F., Weiss, Mary C.
Publicado 1998

Reverse Epidemiology: An Experimental Framework to Drive Leishmania Biomarker Discovery in situ by Functional Genetic Screening Using Relevant Animal Models

por Piel, Laura, Pescher, Pascale, Späth, Gerald F.
Publicado 2018

Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion

por Rachidi, Najma, Knippschild, Uwe, Späth, Gerald F.
Publicado 2021

The enemy within: Targeting host–parasite interaction for antileishmanial drug discovery

por Lamotte, Suzanne, Späth, Gerald F., Rachidi, Najma, Prina, Eric
Publicado 2017

A Novel Role for Stat1 in Phagosome Acidification and Natural Host Resistance to Intracellular Infection by Leishmania major

por Späth, Gerald F., Schlesinger, Paul, Schreiber, Robert, Beverley, Stephen M.
Publicado 2009

Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit

por Martel, Daniel, Beneke, Tom, Gluenz, Eva, Späth, Gerald F., Rachidi, Najma
Publicado 2017

Infectivity and Drug Susceptibility Profiling of Different Leishmania-Host Cell Combinations

por Baek, Kyung-Hwa, Piel, Laura, Rosazza, Thibault, Prina, Eric, Späth, Gerald F., No, Joo Hwan
Publicado 2020

Nuclear and mitochondrial genome sequencing of North-African Leishmania infantum isolates from cured and relapsed visceral leishmaniasis patients reveals variations correlating wit...

por Bussotti, Giovanni, Benkahla, Alia, Jeddi, Fakhri, Souiaï, Oussama, Aoun, Karim, Späth, Gerald F., Bouratbine, Aïda
Publicado 2020

Transgenic Analysis of the Leishmania MAP Kinase MPK10 Reveals an Auto-inhibitory Mechanism Crucial for Stage-Regulated Activity and Parasite Viability

por Cayla, Mathieu, Rachidi, Najma, Leclercq, Olivier, Schmidt-Arras, Dirk, Rosenqvist, Heidi, Wiese, Martin, Späth, Gerald F.
Publicado 2014

PhosTryp: a phosphorylation site predictor specific for parasitic protozoa of the family trypanosomatidae

por Palmeri, Antonio, Gherardini, Pier Federico, Tsigankov, Polina, Ausiello, Gabriele, Späth, Gerald F, Zilberstein, Dan, Helmer-Citterich, Manuela
Publicado 2011

Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay

por Smirlis, Despina, Dingli, Florent, Sabatet, Valentin, Roth, Aileen, Knippschild, Uwe, Loew, Damarys, Späth, Gerald F., Rachidi, Najma
Publicado 2022

Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage

por Bussotti, Giovanni, Li, Blaise, Pescher, Pascale, Vojtkova, Barbora, Louradour, Isabelle, Pruzinova, Katerina, Sadlova, Jovana, Volf, Petr, Späth, Gerald F.
Publicado 2023

Trans-Atlantic Spillover: Deconstructing the Ecological Adaptation of Leishmania infantum in the Americas

por Boité, Mariana C., Späth, Gerald F., Bussotti, Giovanni, Porrozzi, Renato, Morgado, Fernanda N., Llewellyn, Martin, Schwabl, Philipp, Cupolillo, Elisa
Publicado 2019

Species- and Strain-Specific Adaptation of the HSP70 Super Family in Pathogenic Trypanosomatids

por Drini, Sima, Criscuolo, Alexis, Lechat, Pierre, Imamura, Hideo, Skalický, Tomáš, Rachidi, Najma, Lukeš, Julius, Dujardin, Jean-Claude, Späth, Gerald F.
Publicado 2016

A Subset of Liver NK T Cells Is Activated during Leishmania donovani Infection by CD1d-bound Lipophosphoglycan

por Amprey, Joseph L., Im, Jin S., Turco, Salvatore J., Murray, Henry W., Illarionov, Petr A., Besra, Gurdyal S., Porcelli, Steven A., Späth, Gerald F.
Publicado 2004

Amphotericin B resistance correlates with increased fitness in vitro and in vivo in Leishmania (Mundinia) martiniquensis

por Mano, Chonlada, Kongkaew, Aphisek, Tippawangkosol, Pongsri, Somboon, Pradya, Roytrakul, Sittiruk, Pescher, Pascale, Späth, Gerald F., Uthaipibull, Chairat, Tantiworawit, Adisak, Siriyasatien, Padet, Jariyapan, Narissara
Publicado 2023

Trifloxystrobin blocks the growth of Theileria parasites and is a promising drug to treat Buparvaquone resistance

por Villares, Marie, Lourenço, Nelly, Berthelet, Jeremy, Lamotte, Suzanne, Regad, Leslie, Medjkane, Souhila, Prina, Eric, Rodrigues-Lima, Fernando, Späth, Gerald F., Weitzman, Jonathan B.
Publicado 2022

Leishmania donovani 90 kD Heat Shock Protein – Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity

por Hombach-Barrigah, Antje, Bartsch, Katharina, Smirlis, Despina, Rosenqvist, Heidi, MacDonald, Andrea, Dingli, Florent, Loew, Damarys, Späth, Gerald F., Rachidi, Najma, Wiese, Martin, Clos, Joachim
Publicado 2019