Translatomics: The Global View of Translation

por Zhao, Jing, Qin, Bo, Nikolay, Rainer, Spahn, Christian M. T., Zhang, Gong
Publicado 2019

Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution

por Hilal, Tarek, Yamamoto, Hiroshi, Loerke, Justus, Bürger, Jörg, Mielke, Thorsten, Spahn, Christian M.T.
Publicado 2016

Cryo-EM structure of the Shigella type III needle complex

por Lunelli, Michele, Kamprad, Antje, Bürger, Jörg, Mielke, Thorsten, Spahn, Christian M. T., Kolbe, Michael
Publicado 2020

Visualization of Trna Movements on the Escherichia coli 70s Ribosome during the Elongation Cycle

por Agrawal, Rajendra K., Spahn, Christian M.T., Penczek, Pawel, Grassucci, Robert A., Nierhaus, Knud H., Frank, Joachim
Publicado 2000

Multifaceted Stoichiometry Control of Bacterial Operons Revealed by Deep Proteome Quantification

por Zhao, Jing, Zhang, Hong, Qin, Bo, Nikolay, Rainer, He, Qing-Yu, Spahn, Christian M. T., Zhang, Gong
Publicado 2019

Mechanistic insights into the role of prenyl-binding protein PrBP/δ in membrane dissociation of phosphodiesterase 6

por Qureshi, Bilal M., Schmidt, Andrea, Behrmann, Elmar, Bürger, Jörg, Mielke, Thorsten, Spahn, Christian M. T., Heck, Martin, Scheerer, Patrick
Publicado 2018

Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates

por Grunwald, Stephan, Hopf, Linus V. M., Bock-Bierbaum, Tobias, Lally, Ciara C. M., Spahn, Christian M. T., Daumke, Oliver
Publicado 2020

Structural basis of early translocation events on the ribosome

por Rundlet, Emily J., Holm, Mikael, Schacherl, Magdalena, Natchiar, S. Kundhavai, Altman, Roger B., Spahn, Christian M. T., Myasnikov, Alexander G., Blanchard, Scott C.
Publicado 2021

Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments

por Melo, Arthur A., Sprink, Thiemo, Noel, Jeffrey K., Vázquez-Sarandeses, Elena, van Hoorn, Chris, Mohd, Saif, Loerke, Justus, Spahn, Christian M. T., Daumke, Oliver
Publicado 2022

Structure of the actively translating plant 80S ribosome at 2.2 Å resolution

por Smirnova, Julia, Loerke, Justus, Kleinau, Gunnar, Schmidt, Andrea, Bürger, Jörg, Meyer, Etienne H., Mielke, Thorsten, Scheerer, Patrick, Bock, Ralph, Spahn, Christian M. T., Zoschke, Reimo
Publicado 2023

Cryo-EM captures early ribosome assembly in action

por Qin, Bo, Lauer, Simon M., Balke, Annika, Vieira-Vieira, Carlos H., Bürger, Jörg, Mielke, Thorsten, Selbach, Matthias, Scheerer, Patrick, Spahn, Christian M. T., Nikolay, Rainer
Publicado 2023

Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit

por Muhs, Margarita, Yamamoto, Hiroshi, Ismer, Jochen, Takaku, Hiroaki, Nashimoto, Masayuki, Uchiumi, Toshio, Nakashima, Nobuhiko, Mielke, Thorsten, Hildebrand, Peter W., Nierhaus, Knud H., Spahn, Christian M. T.
Publicado 2011

Asymmetric properties of rod cGMP Phosphodiesterase 6 (PDE6): structural and functional analysis

por Qureshi, Bilal M, Behrmann, Elmar, Schöneberg, Johannes, Loerke, Justus, Bürger, Jörg, Mielke, Thorsten, Giesebrecht, Jan, Noé, Frank, Hofmann, Klaus Peter, Spahn, Christian M T, Heck, Martin
Publicado 2015

Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association

por Sprink, Thiemo, Ramrath, David J. F., Yamamoto, Hiroshi, Yamamoto, Kaori, Loerke, Justus, Ismer, Jochen, Hildebrand, Peter W., Scheerer, Patrick, Bürger, Jörg, Mielke, Thorsten, Spahn, Christian M. T.
Publicado 2016

tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis

por Flis, Julia, Holm, Mikael, Rundlet, Emily J., Loerke, Justus, Hilal, Tarek, Dabrowski, Marylena, Bürger, Jörg, Mielke, Thorsten, Blanchard, Scott C., Spahn, Christian M.T., Budkevich, Tatyana V.
Publicado 2018

It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods

por Qureshi, Bilal M., Behrmann, Elmar, Schöneberg, Johannes, Loerke, Justus, Bürger, Jörg, Mielke, Thorsten, Giesebrecht, Jan, Noé, Frank, Lamb, Trevor D., Hofmann, Klaus Peter, Spahn, Christian M. T., Heck, Martin
Publicado 2018

Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses

por Banchenko, Sofia, Krupp, Ferdinand, Gotthold, Christine, Bürger, Jörg, Graziadei, Andrea, O’Reilly, Francis J., Sinn, Ludwig, Ruda, Olga, Rappsilber, Juri, Spahn, Christian M. T., Mielke, Thorsten, Taylor, Ian A., Schwefel, David
Publicado 2021

A critical period of translational control during brain development at codon resolution

por Harnett, Dermot, Ambrozkiewicz, Mateusz C., Zinnall, Ulrike, Rusanova, Alexandra, Borisova, Ekaterina, Drescher, Amelie N., Couce-Iglesias, Marta, Villamil, Gabriel, Dannenberg, Rike, Imami, Koshi, Münster-Wandowski, Agnieszka, Fauler, Beatrix, Mielke, Thorsten, Selbach, Matthias, Landthaler, Markus, Spahn, Christian M. T., Tarabykin, Victor, Ohler, Uwe, Kraushar, Matthew L.
Publicado 2022

Head swivel on the ribosome facilitates translocation via intra-subunit tRNA hybrid sites

por Ratje, Andreas H., Loerke, Justus, Mikolajka, Aleksandra, Brünner, Matthias, Hildebrand, Peter W., Starosta, Agata L., Dönhöfer, Alexandra, Connell, Sean R., Fucini, Paola, Mielke, Thorsten, Whitford, Paul C., Onuchic, Jose’ N, Yu, Yanan, Sanbonmatsu, Karissa Y., Hartmann, Roland K., Penczek, Pawel A., Wilson, Daniel N., Spahn, Christian M.T.
Publicado 2010

Structures of active melanocortin-4 receptor–Gs-protein complexes with NDP-α-MSH and setmelanotide

por Heyder, Nicolas A., Kleinau, Gunnar, Speck, David, Schmidt, Andrea, Paisdzior, Sarah, Szczepek, Michal, Bauer, Brian, Koch, Anja, Gallandi, Monique, Kwiatkowski, Dennis, Bürger, Jörg, Mielke, Thorsten, Beck-Sickinger, Annette G., Hildebrand, Peter W., Spahn, Christian M. T., Hilger, Daniel, Schacherl, Magdalena, Biebermann, Heike, Hilal, Tarek, Kühnen, Peter, Kobilka, Brian K., Scheerer, Patrick
Publicado 2021