An optimized protocol for rapid, sensitive and robust on-bead ChIP-seq from primary cells

por Texari, Lorane, Spann, Nathanael J., Troutman, Ty D., Sakai, Mashito, Seidman, Jason S., Heinz, Sven
Publicado 2021

Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung

por Sajti, Eniko, Link, Verena M., Ouyang, Zhengyu, Spann, Nathanael J., Westin, Emma, Romanoski, Casey E., Fonseca, Gregory J., Prince, Lawrence S., Glass, Christopher K.
Publicado 2020

ARID1B, a molecular suppressor of erythropoiesis, is essential for the prevention of Monge’s disease

por Azad, Priti, Caldwell, Andrew B., Ramachandran, Srinivasan, Spann, Nathanael J., Akbari, Ali, Villafuerte, Francisco C., Bermudez, Daniela, Zhao, Helen, Poulsen, Orit, Zhou, Dan, Bafna, Vineet, Subramaniam, Shankar, Haddad, Gabriel G.
Publicado 2022

Diverse motif ensembles specify non-redundant DNA binding activities of AP-1 family members in macrophages

por Fonseca, Gregory J., Tao, Jenhan, Westin, Emma M., Duttke, Sascha H., Spann, Nathanael J., Strid, Tobias, Shen, Zeyang, Stender, Joshua D., Sakai, Mashito, Link, Verena M., Benner, Christopher, Glass, Christopher K.
Publicado 2019

Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7

por Switonski, Pawel M., Delaney, Joe R., Bartelt, Luke C., Niu, Chenchen, Ramos-Zapatero, Maria, Spann, Nathanael J., Alaghatta, Akshay, Chen, Toby, Griffin, Emily N., Bapat, Jaidev, Sopher, Bryce L., La Spada, Albert R.
Publicado 2021

Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages

por Eichenfield, Dawn Z, Troutman, Ty Dale, Link, Verena M, Lam, Michael T, Cho, Han, Gosselin, David, Spann, Nathanael J, Lesch, Hanna P, Tao, Jenhan, Muto, Jun, Gallo, Richard L, Evans, Ronald M, Glass, Christopher K
Publicado 2016

Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes

por Bennett, Hunter, Troutman, Ty D., Zhou, Enchen, Spann, Nathanael J., Link, Verena M., Seidman, Jason S., Nickl, Christian K., Abe, Yohei, Sakai, Mashito, Pasillas, Martina P., Marlman, Justin M., Guzman, Carlos, Hosseini, Mojgan, Schnabl, Bernd, Glass, Christopher K.
Publicado 2023

Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages

por Muse, Evan D., Yu, Shan, Edillor, Chantle R., Tao, Jenhan, Spann, Nathanael J., Troutman, Ty D., Seidman, Jason S., Henke, Adam, Roland, Jason T., Ozeki, Katherine A., Thompson, Bonne M., McDonald, Jeffrey G., Bahadorani, John, Tsimikas, Sotirios, Grossman, Tamar R., Tremblay, Matthew S., Glass, Christopher K.
Publicado 2018

SALL1 enforces microglia-specific DNA binding and function of SMADs to establish microglia identity

por Fixsen, Bethany R., Han, Claudia Z., Zhou, Yi, Spann, Nathanael J., Saisan, Payam, Shen, Zeyang, Balak, Christopher, Sakai, Mashito, Cobo, Isidoro, Holtman, Inge R., Warden, Anna S., Ramirez, Gabriela, Collier, Jana G., Pasillas, Martina P., Yu, Miao, Hu, Rong, Li, Bin, Belhocine, Sarah, Gosselin, David, Coufal, Nicole G., Ren, Bing, Glass, Christopher K.
Publicado 2023

The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

por Blanc, Mathieu, Hsieh, Wei Yuan, Robertson, Kevin A., Kropp, Kai A., Forster, Thorsten, Shui, Guanghou, Lacaze, Paul, Watterson, Steven, Griffiths, Samantha J., Spann, Nathanael J., Meljon, Anna, Talbot, Simon, Krishnan, Kathiresan, Covey, Douglas F., Wenk, Markus R., Craigon, Marie, Ruzsics, Zsolts, Haas, Jürgen, Angulo, Ana, Griffiths, William J., Glass, Christopher K., Wang, Yuqin, Ghazal, Peter
Publicado 2013

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions

por Hoeksema, Marten A, Gijbels, Marion JJ, Van den Bossche, Jan, van der Velden, Saskia, Sijm, Ayestha, Neele, Annette E, Seijkens, Tom, Stöger, J Lauran, Meiler, Svenja, Boshuizen, Marieke CS, Dallinga-Thie, Geesje M, Levels, Johannes HM, Boon, Louis, Mullican, Shannon E, Spann, Nathanael J, Cleutjens, Jack P, Glass, Chris K, Lazar, Mitchell A, de Vries, Carlie JM, Biessen, Erik AL, Daemen, Mat JAP, Lutgens, Esther, de Winther, Menno PJ
Publicado 2014