Enrichment and Liquid Chromatography–Mass Spectrometry Analysis of Trastuzumab and Pertuzumab Using Affimer Reagents

por Olaleye, Oladapo, Spanov, Baubek, Ford, Robert, Govorukhina, Natalia, van de Merbel, Nico C., Bischoff, Rainer
Publicado 2021

Effect of Trastuzumab–HER2 Complex Formation on Stress-Induced Modifications in the CDRs of Trastuzumab

por Spanov, Baubek, Aboagye, Victoria, Olaleye, Oladapo, Govorukhina, Natalia, van de Merbel, Nico C., Bischoff, Rainer
Publicado 2022

Determination of Binding Sites on Trastuzumab and Pertuzumab to Selective Affimers Using Hydrogen–Deuterium Exchange Mass Spectrometry

por Olaleye, Oladapo, Graf, Christian, Spanov, Baubek, Govorukhina, Natalia, Groves, Matthew R., van de Merbel, Nico C., Bischoff, Rainer
Publicado 2023

Revealing charge heterogeneity of stressed trastuzumab at the subunit level

por Spanov, Baubek, Baartmans, Bas, Olaleye, Oladapo, Nicolardi, Simone, Govorukhina, Natalia, Wuhrer, Manfred, van de Merbel, Nico C., Bischoff, Rainer
Publicado 2023

Pertuzumab Charge Variant Analysis and Complementarity-Determining Region Stability Assessment to Deamidation

por Spanov, Baubek, Olaleye, Oladapo, Mesurado, Tomés, Govorukhina, Natalia, Jungbauer, Alois, van de Merbel, Nico C., Lingg, Nico, Bischoff, Rainer
Publicado 2023