Direct Involvement of Retinoblastoma Family Proteins in DNA Repair by Non-homologous End-Joining

por Cook, Rebecca, Zoumpoulidou, Georgia, Luczynski, Maciej T., Rieger, Simone, Moquet, Jayne, Spanswick, Victoria J., Hartley, John A., Rothkamm, Kai, Huang, Paul H., Mittnacht, Sibylle
Publicado 2015

Evidence for different mechanisms of ‘unhooking’ for melphalan and cisplatin-induced DNA interstrand cross-links in vitro and in clinical acquired resistant tumour samples

por Spanswick, Victoria J, Lowe, Helen L, Newton, Claire, Bingham, John P, Bagnobianchi, Alessia, Kiakos, Konstantinos, Craddock, Charles, Ledermann, Jonathan A, Hochhauser, Daniel, Hartley, John A
Publicado 2012

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment

por Ip, Laura R. H., Poulogiannis, George, Viciano, Felipe Cia, Sasaki, Junko, Kofuji, Satoshi, Spanswick, Victoria J., Hochhauser, Daniel, Hartley, John A., Sasaki, Takehiko, Gewinner, Christina A.
Publicado 2015

Activity of the DNA minor groove cross-linking agent SG2000 (SJG-136) against canine tumours

por Mellinas-Gomez, Maria, Spanswick, Victoria J., Paredes-Moscosso, Solange R., Robson, Matthew, Pedley, R. Barbara, Thurston, David E., Baines, Stephen J., Stell, Anneliese, Hartley, John A.
Publicado 2015

PANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer

por Propper, David J., Gao, Fangfei, Saunders, Mark P., Sarker, Debashis, Hartley, John A., Spanswick, Victoria J., Lowe, Helen L., Hackett, Louise D., Ng, Tony T., Barber, Paul R., Weitsman, Gregory E., Pearce, Sarah, White, Laura, Lopes, Andre, Forsyth, Sharon, Hochhauser, Daniel
Publicado 2022