Small-Molecule Lysophosphatidic Acid Receptor 5 (LPAR5) Antagonists: Versatile Pharmacological Tools to Regulate Inflammatory Signaling in BV-2 Microglia Cells

por Plastira, Ioanna, Joshi, Lisha, Bernhart, Eva, Schoene, Jens, Specker, Edgar, Nazare, Marc, Sattler, Wolfgang
Publicado 2019

Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway

por Klein, Wolfgang, Rutz, Claudia, Eckhard, Jamina, Provinciael, Becky, Specker, Edgar, Neuenschwander, Martin, Kleinau, Gunnar, Scheerer, Patrick, von Kries, Jens-Peter, Nazaré, Marc, Vermeire, Kurt, Schülein, Ralf
Publicado 2018

Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis

por Bonnekoh, Hanna, Vera, Carolina, Abad‐Perez, Angela, Radetzki, Silke, Neuenschwander, Martin, Specker, Edgar, Mahnke, Niklas Amadeus, Frischbutter, Stefan, Latz, Eicke, Nazaré, Marc, Kries, Jens v., Maurer, Marcus, Scheffel, Jörg, Krause, Karoline
Publicado 2021

Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1

por Juneja, Manisha, Kobelt, Dennis, Walther, Wolfgang, Voss, Cynthia, Smith, Janice, Specker, Edgar, Neuenschwander, Martin, Gohlke, Björn-Oliver, Dahlmann, Mathias, Radetzki, Silke, Preissner, Robert, von Kries, Jens Peter, Schlag, Peter Michael, Stein, Ulrike
Publicado 2017

NMR quality control of fragment libraries for screening

por Sreeramulu, Sridhar, Richter, Christian, Kuehn, Till, Azzaoui, Kamal, Blommers, Marcel Jules José, Del Conte, Rebecca, Fragai, Marco, Trieloff, Nils, Schmieder, Peter, Nazaré, Marc, Specker, Edgar, Ivanov, Vladimir, Oschkinat, Hartmut, Banci, Lucia, Schwalbe, Harald
Publicado 2020

Small molecule inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation

por Jordan, Philipp, Costa, Amanda, Specker, Edgar, Popp, Oliver, Volkamer, Andrea, Piske, Regina, Obrusnik, Tessa, Kleissle, Sabrina, Stuke, Kevin, Rex, Andre, Neuenschwander, Martin, von Kries, Jens Peter, Nazare, Marc, Mertins, Phillip, Kettenmann, Helmut, Wolf, Susanne A.
Publicado 2023

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

por Brennecke, Philip, Rasina, Dace, Aubi, Oscar, Herzog, Katja, Landskron, Johannes, Cautain, Bastien, Vicente, Francisca, Quintana, Jordi, Mestres, Jordi, Stechmann, Bahne, Ellinger, Bernhard, Brea, Jose, Kolanowski, Jacek L., Pilarski, Radosław, Orzaez, Mar, Pineda-Lucena, Antonio, Laraia, Luca, Nami, Faranak, Zielenkiewicz, Piotr, Paruch, Kamil, Hansen, Espen, von Kries, Jens P., Neuenschwander, Martin, Specker, Edgar, Bartunek, Petr, Simova, Sarka, Leśnikowski, Zbigniew, Krauss, Stefan, Lehtiö, Lari, Bilitewski, Ursula, Brönstrup, Mark, Taskén, Kjetil, Jirgensons, Aigars, Lickert, Heiko, Clausen, Mads H., Andersen, Jeanette H., Vicent, Maria J., Genilloud, Olga, Martinez, Aurora, Nazaré, Marc, Fecke, Wolfgang, Gribbon, Philip
Publicado 2019