Predictive Value of EGFR-PI3K-AKT-mTOR-Pathway Inhibitor Biomarkers for Head and Neck Squamous Cell Carcinoma: A Systematic Review

por de Kort, W. W. B., Spelier, S., Devriese, L. A., van Es, R. J. J., Willems, S. M.
Publicado 2021

Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy

por Driehuis, Else, Spelier, Sacha, Beltrán Hernández, Irati, de Bree, Remco, M. Willems, Stefan, Clevers, Hans, Oliveira, Sabrina
Publicado 2019

CFTR Rescue in Intestinal Organoids with GLPG/ABBV-2737, ABBV/GLPG-2222 and ABBV/GLPG-2451 Triple Therapy

por de Poel, Eyleen, Spelier, Sacha, Korporaal, Ricardo, Lai, Ka Wai, Boj, Sylvia F., Conrath, Katja, van der Ent, Cornelis K., Beekman, Jeffrey M.
Publicado 2021

High-throughput functional assay in cystic fibrosis patient-derived organoids allows drug repurposing

por Spelier, Sacha, de Poel, Eyleen, Ithakisiou, Georgia N., Suen, Sylvia W.F., Hagemeijer, Marne C., Muilwijk, Danya, Vonk, Annelotte M., Brunsveld, Jesse E., Kruisselbrink, Evelien, van der Ent, Cornelis K., Beekman, Jeffrey M.
Publicado 2023

Mutation-specific reporter for optimization and enrichment of prime editing

por Schene, I. F., Joore, I. P., Baijens, J. H. L., Stevelink, R., Kok, G., Shehata, S., Ilcken, E. F., Nieuwenhuis, E. C. M., Bolhuis, D. P., van Rees, R. C. M., Spelier, S. A., van der Doef, H. P. J., Beekman, J. M., Houwen, R. H. J., Nieuwenhuis, E. E. S., Fuchs, S. A.
Publicado 2022

Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia

por Amatngalim, Gimano D, Rodenburg, Lisa W, Aalbers, Bente L, Raeven, Henriette HM, Aarts, Ellen M, Sarhane, Dounia, Spelier, Sacha, Lefferts, Juliet W, Silva, Iris AL, Nijenhuis, Wilco, Vrendenbarg, Sacha, Kruisselbrink, Evelien, Brunsveld, Jesse E, van Drunen, Cornelis M, Michel, Sabine, de Winter-de Groot, Karin M, Heijerman, Harry G, Kapitein, Lukas C, Amaral, Magarida D, van der Ent, Cornelis K, Beekman, Jeffrey M
Publicado 2022