Preclinical and Healthy Volunteer Studies of Potential Drug–Drug Interactions Between Tenapanor and Phosphate Binders

por Johansson, Susanne, Leonsson‐Zachrisson, Maria, Knutsson, Mikael, Spencer, Andrew G., Labonté, Eric D., Deshpande, Desiree, Kohler, Jill, Kozuka, Kenji, Charmot, Dominique, Rosenbaum, David P.
Publicado 2016

Discovery of Tenapanor: A First-in-Class Minimally Systemic Inhibitor of Intestinal Na(+)/H(+) Exchanger Isoform 3

por Jacobs, Jeffrey W., Leadbetter, Michael R., Bell, Noah, Koo-McCoy, Samantha, Carreras, Christopher W., He, Limin, Kohler, Jill, Kozuka, Kenji, Labonté, Eric D., Navre, Marc, Spencer, Andrew G., Charmot, Dominique
Publicado 2022

OR26-03 Treatment With Linsitinib, An IGF-1 Receptor Inhibitor, Prevents Disease Development And Progression In An Experimental Model Of Thyroid Eye Disease

por Gulbins, Anne, Horstmann, Mareike, Daser, Anke, Flögel, Ulrich, Oeverhaus, Michael, Nikolaos, Bechrakis E, Paul Banga, J, Krause, Gerd, Hammer, Gary D, Spencer, Andrew G, Zeidan, Ryan, Eckstein, Anja, Philipp, Svenja, Görtz, Gina-Eva
Publicado 2023

Linsitinib, an IGF-1R inhibitor, attenuates disease development and progression in a model of thyroid eye disease

por Gulbins, Anne, Horstmann, Mareike, Daser, Anke, Flögel, Ulrich, Oeverhaus, Michael, Bechrakis, Nikolaos E., Banga, J. Paul, Keitsch, Simone, Wilker, Barbara, Krause, Gerd, Hammer, Gary D., Spencer, Andrew G., Zeidan, Ryan, Eckstein, Anja, Philipp, Svenja, Görtz, Gina-Eva
Publicado 2023

Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown mice

por De Souza, Angus T., Dai, Xudong, Spencer, Andrew G., Reppen, Tom, Menzie, Ann, Roesch, Paula L., He, Yudong, Caguyong, Michelle J., Bloomer, Sherri, Herweijer, Hans, Wolff, Jon A., Hagstrom, James E., Lewis, David L., Linsley, Peter S., Ulrich, Roger G.
Publicado 2006