Perspectives on Human Genetic Variation from the HapMap Project

por McVean, Gil, Spencer, Chris C. A, Chaix, Raphaelle
Publicado 2005

Progress and promise in understanding the genetic basis of common diseases

por Price, Alkes L., Spencer, Chris C. A., Donnelly, Peter
Publicado 2015

Designing Genome-Wide Association Studies: Sample Size, Power, Imputation, and the Choice of Genotyping Chip

por Spencer, Chris C. A., Su, Zhan, Donnelly, Peter, Marchini, Jonathan
Publicado 2009

A robust clustering algorithm for identifying problematic samples in genome-wide association studies

por Bellenguez, Céline, Strange, Amy, Freeman, Colin, Donnelly, Peter, Spencer, Chris C.A.
Publicado 2012

FINEMAP: efficient variable selection using summary data from genome-wide association studies

por Benner, Christian, Spencer, Chris C.A., Havulinna, Aki S., Salomaa, Veikko, Ripatti, Samuli, Pirinen, Matti
Publicado 2016

Impact of IFNL4 Genetic Variants on Sustained Virologic Response and Viremia in Hepatitis C Virus Genotype 3 Patients

por Pedergnana, Vincent, Irving, William L., Barnes, Eleanor, McLauchlan, John, Spencer, Chris C.A.
Publicado 2019

Interferon lambda 4 variant rs12979860 is not associated with RAV NS5A Y93H in hepatitis C virus genotype 3a

por Pedergnana, Vincent, Smith, David, Klenerman, Paul, Barnes, Eleanor, Spencer, Chris C. A., Ansari, M. Azim
Publicado 2016

The Influence of Recombination on Human Genetic Diversity

por Spencer, Chris C. A, Deloukas, Panos, Hunt, Sarah, Mullikin, Jim, Myers, Simon, Silverman, Bernard, Donnelly, Peter, Bentley, David, McVean, Gil
Publicado 2006

Impact of Interferon Lambda 4 Genotype on Interferon‐Stimulated Gene Expression During Direct‐Acting Antiviral Therapy for Hepatitis C

por Ramamurthy, Narayan, Marchi, Emanuele, Ansari, M. Azim, Pedergnana, Vincent, Mclean, Angela, Hudson, Emma, Bowden, Rory, Spencer, Chris C.A., Barnes, Eleanor, Klenerman, Paul
Publicado 2018

Pneumococcal genome sequencing tracks a vaccine escape variant formed through a multi-fragment recombination event

por Golubchik, Tanya, Brueggemann, Angela B., Street, Teresa, Gertz, Robert E., Spencer, Chris C. A., Ho, Thien, Giannoulatou, Eleni, Link-Gelles, Ruth, Harding, Rosalind M., Beall, Bernard, Peto, Tim E. A., Moore, Matthew R., Donnelly, Peter, Crook, Derrick W., Bowden, Rory
Publicado 2012

Genetic Analysis in UK Biobank Links Insulin Resistance and Transendothelial Migration Pathways to Coronary Artery Disease

por Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A., Chaffin, Mark, Horner, Steven, McMillan, Brian J., Leed, Alison, Weale, Michael E., Spencer, Chris C. A., Aguet, François, Segrè, Ayellet V., Ardlie, Kristin G., Khera, Amit V., Kaushik, Virendar K., Natarajan, Pradeep, Consortium, CARDIoGRAMplusC4D, Kathiresan, Sekar
Publicado 2017

Integrated Polygenic Tool Substantially Enhances Coronary Artery Disease Prediction

por Riveros-Mckay, Fernando, Weale, Michael E., Moore, Rachel, Selzam, Saskia, Krapohl, Eva, Sivley, R. Michael, Tarran, William A., Sørensen, Peter, Lachapelle, Alexander S., Griffiths, Jonathan A., Saffari, Ayden, Deanfield, John, Spencer, Chris C.A., Hippisley-Cox, Julia, Hunter, David J., O’Sullivan, Jack W., Ashley, Euan A., Plagnol, Vincent, Donnelly, Peter
Publicado 2021

Genome-to-genome analysis highlights the impact of the human innate and adaptive immune systems on the hepatitis C virus

por Ansari, M. Azim, Pedergnana, Vincent, Ip, Camilla, Magri, Andrea, Von Delft, Annette, Bonsall, David, Chaturvedi, Nimisha, Bartha, Istvan, Smith, David, Nicholson, George, McVean, Gilean, Trebes, Amy, Piazza, Paolo, Fellay, Jacques, Cooke, Graham, Foster, Graham R, Hudson, Emma, McLauchlan, John, Simmonds, Peter, Bowden, Rory, Klenerman, Paul, Barnes, Eleanor, Spencer, Chris C. A.
Publicado 2017

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4

por Gilchrist, James J., Rautanen, Anna, Fairfax, Benjamin P., Mills, Tara C., Naranbhai, Vivek, Trochet, Holly, Pirinen, Matti, Muthumbi, Esther, Mwarumba, Salim, Njuguna, Patricia, Mturi, Neema, Msefula, Chisomo L., Gondwe, Esther N., MacLennan, Jenny M., Chapman, Stephen J., Molyneux, Malcolm E., Knight, Julian C., Spencer, Chris C. A., Williams, Thomas N., MacLennan, Calman A., Scott, J. Anthony G., Hill, Adrian V. S.
Publicado 2018

Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations

por Band, Gavin, Le, Quang Si, Jostins, Luke, Pirinen, Matti, Kivinen, Katja, Jallow, Muminatou, Sisay-Joof, Fatoumatta, Bojang, Kalifa, Pinder, Margaret, Sirugo, Giorgio, Conway, David J., Nyirongo, Vysaul, Kachala, David, Molyneux, Malcolm, Taylor, Terrie, Ndila, Carolyne, Peshu, Norbert, Marsh, Kevin, Williams, Thomas N., Alcock, Daniel, Andrews, Robert, Edkins, Sarah, Gray, Emma, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Schuldt, Kathrin, Clark, Taane G., Small, Kerrin S., Teo, Yik Ying, Kwiatkowski, Dominic P., Rockett, Kirk A., Barrett, Jeffrey C., Spencer, Chris C. A.
Publicado 2013

Correction: Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations

por Band, Gavin, Le, Quang Si, Jostins, Luke, Pirinen, Matti, Kivinen, Katja, Jallow, Muminatou, Sisay-Joof, Fatoumatta, Bojang, Kalifa, Pinder, Margaret, Sirugo, Giorgio, Conway, David J., Nyirongo, Vysaul, Kachala, David, Molyneux, Malcolm, Taylor, Terrie, Ndila, Carolyne, Peshu, Norbert, Marsh, Kevin, Williams, Thomas N., Alcock, Daniel, Andrews, Robert, Edkins, Sarah, Gray, Emma, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Schuldt, Kathrin, Clark, Taane G., Small, Kerrin S., Teo, Yik Ying, Kwiatkowski, Dominic P., Rockett, Kirk A., Barrett, Jeffrey C., Spencer, Chris C. A.
Publicado 2013

Phenome-wide association studies across large population cohorts support drug target validation

por Diogo, Dorothée, Tian, Chao, Franklin, Christopher S., Alanne-Kinnunen, Mervi, March, Michael, Spencer, Chris C. A., Vangjeli, Ciara, Weale, Michael E., Mattsson, Hannele, Kilpeläinen, Elina, Sleiman, Patrick M. A., Reilly, Dermot F., McElwee, Joshua, Maranville, Joseph C., Chatterjee, Arnaub K., Bhandari, Aman, Nguyen, Khanh-Dung H., Estrada, Karol, Reeve, Mary-Pat, Hutz, Janna, Bing, Nan, John, Sally, MacArthur, Daniel G., Salomaa, Veikko, Ripatti, Samuli, Hakonarson, Hakon, Daly, Mark J., Palotie, Aarno, Hinds, David A., Donnelly, Peter, Fox, Caroline S., Day-Williams, Aaron G., Plenge, Robert M., Runz, Heiko
Publicado 2018

Dissection of the genetics of Parkinson's disease identifies an additional association 5′ of SNCA and multiple associated haplotypes at 17q21

por Spencer, Chris C.A., Plagnol, Vincent, Strange, Amy, Gardner, Michelle, Paisan-Ruiz, Coro, Band, Gavin, Barker, Roger A., Bellenguez, Celine, Bhatia, Kailash, Blackburn, Hannah, Blackwell, Jennie M., Bramon, Elvira, Brown, Martin A., Brown, Matthew A., Burn, David, Casas, Juan-Pablo, Chinnery, Patrick F., Clarke, Carl E., Corvin, Aiden, Craddock, Nicholas, Deloukas, Panos, Edkins, Sarah, Evans, Jonathan, Freeman, Colin, Gray, Emma, Hardy, John, Hudson, Gavin, Hunt, Sarah, Jankowski, Janusz, Langford, Cordelia, Lees, Andrew J., Markus, Hugh S., Mathew, Christopher G., McCarthy, Mark I., Morrison, Karen E., Palmer, Colin N.A., Pearson, Justin P., Peltonen, Leena, Pirinen, Matti, Plomin, Robert, Potter, Simon, Rautanen, Anna, Sawcer, Stephen J., Su, Zhan, Trembath, Richard C., Viswanathan, Ananth C., Williams, Nigel W., Morris, Huw R., Donnelly, Peter, Wood, Nicholas W.
Publicado 2011

Common variants in the HLA-DRB1-HLA-DQA1 Class II region are associated with susceptibility to visceral leishmaniasis

por Fakiola, Michaela, Strange, Amy, Cordell, Heather J., Miller, E. Nancy, Pirinen, Matti, Su, Zhan, Mishra, Anshuman, Mehrotra, Sanjana, Monteiro, Gloria R., Band, Gavin, Bellenguez, Céline, Dronov, Serge, Edkins, Sarah, Freeman, Colin, Giannoulatou, Eleni, Gray, Emma, Hunt, Sarah E., Lacerda, Henio G., Langford, Cordelia, Pearson, Richard, Pontes, Núbia N., Rai, Madhukar, Singh, S.P., Smith, Linda, Sousa, Olivia, Vukcevic, Damjan, Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N.A., Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C., Wood, Nicholas W., Wilson, Mary E., Deloukas, Panos, Peltonen, Leena, Christiansen, Frank, Witt, Campbell, Jeronimo, Selma M.B., Sundar, Shyam, Spencer, Chris C.A., Blackwell, Jenefer M., Donnelly, Peter
Publicado 2013

An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis

por Morris, Derek W., Pearson, Richard D., Cormican, Paul, Kenny, Elaine M., O'Dushlaine, Colm T., Perreault, Louis-Philippe Lemieux, Giannoulatou, Eleni, Tropea, Daniela, Maher, Brion S., Wormley, Brandon, Kelleher, Eric, Fahey, Ciara, Molinos, Ines, Bellini, Stefania, Pirinen, Matti, Strange, Amy, Freeman, Colin, Thiselton, Dawn L., Elves, Rachel L., Regan, Regina, Ennis, Sean, Dinan, Timothy G., McDonald, Colm, Murphy, Kieran C., O'Callaghan, Eadbhard, Waddington, John L., Walsh, Dermot, O'Donovan, Michael, Grozeva, Detelina, Craddock, Nick, Stone, Jennifer, Scolnick, Ed, Purcell, Shaun, Sklar, Pamela, Coe, Bradley, Eichler, Evan E., Ophoff, Roel, Buizer, Jacobine, Szatkiewicz, Jin, Hultman, Christina, Sullivan, Patrick, Gurling, Hugh, Mcquillin, Andrew, St Clair, David, Rees, Elliott, Kirov, George, Walters, James, Blackwood, Douglas, Johnstone, Mandy, Donohoe, Gary, O'Neill, Francis A., Kendler, Kenneth S., Gill, Michael, Riley, Brien P., Spencer, Chris C. A., Corvin, Aiden
Publicado 2014