A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice

por Wehling, Michelle, Spencer, Melissa J., Tidball, James G.
Publicado 2001

Successes and challenges in clinical gene therapy

por Kohn, Donald B., Chen, Yvonne Y., Spencer, Melissa J.
Publicado 2023

Calpain 3 and CaMKIIβ signaling are required to induce HSP70 necessary for adaptive muscle growth after atrophy

por Kramerova, Irina, Torres, Jorge A, Eskin, Ascia, Nelson, Stanley F, Spencer, Melissa J
Publicado 2018

Genome Editing-Mediated Utrophin Upregulation in Duchenne Muscular Dystrophy Stem Cells

por Sengupta, Kasturi, Mishra, Manoj K., Loro, Emanuele, Spencer, Melissa J., Pyle, April D., Khurana, Tejvir S.
Publicado 2020

A reporter mouse for optical imaging of inflammation in mdx muscles

por Martinez, Leonel, Ermolova, Natalia V, Ishikawa, Tomo-O, Stout, David B, Herschman, Harvey R, Spencer, Melissa J
Publicado 2015

Osteopontin ablation ameliorates muscular dystrophy by shifting macrophages to a pro-regenerative phenotype

por Capote, Joana, Kramerova, Irina, Martinez, Leonel, Vetrone, Sylvia, Barton, Elisabeth R., Sweeney, H. Lee, Miceli, M. Carrie, Spencer, Melissa J.
Publicado 2016

High levels of sarcospan are well tolerated and act as a sarcolemmal stabilizer to address skeletal muscle and pulmonary dysfunction in DMD

por Gibbs, Elizabeth M., Marshall, Jamie L., Ma, Eva, Nguyen, Thien M., Hong, Grace, Lam, Jessica S., Spencer, Melissa J., Crosbie-Watson, Rachelle H.
Publicado 2016

Nanoparticles systemically biodistribute to regenerating skeletal muscle in DMD

por Hicks, Michael R., Liu, Xiangsheng, Young, Courtney S., Saleh, Kholoud, Ji, Ying, Jiang, Jinhong, Emami, Michael R., Mokhonova, Ekaterina, Spencer, Melissa J., Meng, Huan, Pyle, April D.
Publicado 2023

Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation

por Yao, Jiayi, Guihard, Pierre J., Wu, Xiuju, Blazquez-Medela, Ana M., Spencer, Melissa J., Jumabay, Medet, Tontonoz, Peter, Fogelman, Alan M., Boström, Kristina I., Yao, Yucheng
Publicado 2017

Repurposing Dantrolene for Long-Term Combination Therapy to Potentiate Antisense-Mediated DMD Exon Skipping in the mdx Mouse

por Wang, Derek W., Mokhonova, Ekaterina I., Kendall, Genevieve C., Becerra, Diana, Naeini, Yalda B., Cantor, Rita M., Spencer, Melissa J., Nelson, Stanley F., Miceli, M. Carrie
Publicado 2018

A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy

por Liu, Jian, Campagna, Jesus, John, Varghese, Damoiseaux, Robert, Mokhonova, Ekaterina, Becerra, Diana, Meng, Huan, McNally, Elizabeth M., Pyle, April D., Kramerova, Irina, Spencer, Melissa J.
Publicado 2020

Single cell sequencing maps skeletal muscle cellular diversity as disease severity increases in dystrophic mouse models

por Saleh, Kholoud K., Xi, Haibin, Switzler, Corey, Skuratovsky, Emily, Romero, Matthew A., Chien, Peggie, Gibbs, Devin, Gane, Lily, Hicks, Michael R., Spencer, Melissa J., Pyle, April D.
Publicado 2022

Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury

por Quattrocelli, Mattia, Capote, Joanna, Ohiri, Joyce C., Warner, James L., Vo, Andy H., Earley, Judy U., Hadhazy, Michele, Demonbreun, Alexis R., Spencer, Melissa J., McNally, Elizabeth M.
Publicado 2017

Innate and adaptive AAV-mediated immune responses in a mouse model of Duchenne muscular dystrophy

por Emami, Michael R., Espinoza, Alejandro, Young, Courtney S., Ma, Feiyang, Farahat, Philip K., Felgner, Philip L., Chamberlain, Jeffrey S., Xu, Xiangmin, Pyle, April D., Pellegrini, Matteo, Villalta, S. Armando, Spencer, Melissa J.
Publicado 2023

Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization

por Chao, Lily C., Wroblewski, Kevin, Ilkayeva, Olga R., Stevens, Robert D., Bain, James, Meyer, Gretchen A., Schenk, Simon, Martinez, Leonel, Vergnes, Laurent, Narkar, Vihang A., Drew, Brian G., Hong, Cynthia, Boyadjian, Rima, Hevener, Andrea L., Evans, Ronald M., Reue, Karen, Spencer, Melissa J., Newgard, Christopher B., Tontonoz, Peter
Publicado 2012

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

por Coulis, Gerald, Jaime, Diego, Guerrero-Juarez, Christian, Kastenschmidt, Jenna M., Farahat, Philip K., Nguyen, Quy, Pervolarakis, Nicholas, McLinden, Katherine, Thurlow, Lauren, Movahedi, Saba, Duarte, Jorge, Sorn, Andrew, Montoya, Elizabeth, Mozaffar, Izza, Dragan, Morgan, Othy, Shivashankar, Joshi, Trupti, Hans, Chetan P., Kimonis, Virginia, MacLean, Adam L., Nie, Qing, Wallace, Lindsay M., Harper, Scott Q., Mozaffar, Tahseen, Hogarth, Marshall W., Bhattacharya, Surajit, Jaiswal, Jyoti K., Golann, David R., Su, Qi, Kessenbrock, Kai, Stec, Michael, Spencer, Melissa J., Zamudio, Jesse R., Villalta, S. Armando
Publicado 2023

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

por Coulis, Gerald, Jaime, Diego, Guerrero-Juarez, Christian, Kastenschmidt, Jenna M., Farahat, Philip K., Nguyen, Quy, Pervolarakis, Nicholas, McLinden, Katherine, Thurlow, Lauren, Movahedi, Saba, Hughes, Brandon S., Duarte, Jorge, Sorn, Andrew, Montoya, Elizabeth, Mozaffar, Izza, Dragan, Morgan, Othy, Shivashankar, Joshi, Trupti, Hans, Chetan P., Kimonis, Virginia, MacLean, Adam L., Nie, Qing, Wallace, Lindsay M., Harper, Scott Q., Mozaffar, Tahseen, Hogarth, Marshall W., Bhattacharya, Surajit, Jaiswal, Jyoti K., Golann, David R., Su, Qi, Kessenbrock, Kai, Stec, Michael, Spencer, Melissa J., Zamudio, Jesse R., Villalta, S. Armando
Publicado 2023