Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics

por Suzuki, Hiroshi I., Spengler, Ryan M., Grigelioniene, Giedre, Kobayashi, Tatsuya, Sharp, Phillip A.
Publicado 2018

Cis-acting single nucleotide polymorphisms alter MicroRNA-mediated regulation of human brain-expressed transcripts

por Ramachandran, Shyam, Coffin, Stephanie L., Tang, Tin-Yun, Jobaliya, Chintan D., Spengler, Ryan M., Davidson, Beverly L.
Publicado 2016

Men who inject opioids exhibit altered tRNA-Gly-GCC isoforms in semen

por Gornalusse, Germán, Spengler, Ryan M, Sandford, Erin, Kim, Yeseul, Levy, Claire, Tewari, Muneesh, Hladik, Florian, Vojtech, Lucia
Publicado 2023

Adenosine deamination in human transcripts generates novel microRNA binding sites

por Borchert, Glen M., Gilmore, Brian L., Spengler, Ryan M., Xing, Yi, Lanier, William, Bhattacharya, Debashish, Davidson, Beverly L.
Publicado 2009

The long non-coding RNA NEAT1 is elevated in polyglutamine repeat expansion diseases and protects from disease gene-dependent toxicities

por Cheng, Congsheng, Spengler, Ryan M, Keiser, Megan S, Monteys, Alejandro Mas, Rieders, Julianne M, Ramachandran, Shyam, Davidson, Beverly L
Publicado 2018

siSPOTR: a tool for designing highly specific and potent siRNAs for human and mouse

por Boudreau, Ryan L., Spengler, Ryan M., Hylock, Ray H., Kusenda, Brandyn J., Davis, Heather A., Eichmann, David A., Davidson, Beverly L.
Publicado 2013

Phospho‐RNA‐seq: a modified small RNA‐seq method that reveals circulating mRNA and lncRNA fragments as potential biomarkers in human plasma

por Giraldez, Maria D, Spengler, Ryan M, Etheridge, Alton, Goicochea, Annika J, Tuck, Missy, Choi, Sung Won, Galas, David J, Tewari, Muneesh
Publicado 2019

Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP

por Spengler, Ryan M., Zhang, Xiaoming, Cheng, Congsheng, McLendon, Jared M., Skeie, Jessica M., Johnson, Frances L., Davidson, Beverly L., Boudreau, Ryan L.
Publicado 2016

Single nucleotide seed modification restores in vivo tolerability of a toxic artificial miRNA sequence in the mouse brain

por Monteys, Alex Mas, Spengler, Ryan M., Dufour, Brett D., Wilson, Matt S., Oakley, Clayton K., Sowada, Matt J., McBride, Jodi L., Davidson, Beverly L.
Publicado 2014

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma

por Haring, Catherine T., Bhambhani, Chandan, Brummel, Collin, Jewell, Brittany, Bellile, Emily, Heft Neal, Molly E., Sandford, Erin, Spengler, Ryan M., Bhangale, Apurva, Spector, Matthew E., McHugh, Jonathan, Prince, Mark E., Mierzwa, Michelle, Worden, Francis P., Tewari, Muneesh, Swiecicki, Paul L., Brenner, J. Chad
Publicado 2021

Open Problems in Extracellular RNA Data Analysis: Insights From an ERCC Online Workshop

por Alexander, Roger P., Kitchen, Robert R, Tosar, Juan Pablo, Roth, Matthew, Mestdagh, Pieter, Max, Klaas E. A., Rozowsky, Joel, Kaczor-Urbanowicz, Karolina Elżbieta, Chang, Justin, Balaj, Leonora, Losic, Bojan, Van Nostrand, Eric L., LaPlante, Emily, Mateescu, Bogdan, White, Brian S., Yu, Rongshan, Milosavljevic, Aleksander, Stolovitzky, Gustavo, Spengler, Ryan M.
Publicado 2022