Intraocular DHODH-inhibitor PP-001 suppresses relapsing experimental uveitis and cytokine production of human lymphocytes, but not of RPE cells

por Diedrichs-Möhring, Maria, Niesik, Sandy, Priglinger, Claudia S., Thurau, Stephan R., Obermayr, Franz, Sperl, Stefan, Wildner, Gerhild
Publicado 2018

A new small molecule DHODH-inhibitor [KIO-100 (PP-001)] targeting activated T cells for intraocular treatment of uveitis — A phase I clinical trial

por Thurau, Stephan, Deuter, Christoph M. E., Heiligenhaus, Arnd, Pleyer, Uwe, Van Calster, Joachim, Barisani-Asenbauer, Talin, Obermayr, Franz, Sperl, Stefan, Seda-Zehetner, Romana, Wildner, Gerhild
Publicado 2022