Respiratory infections predominate after day 100 following B-cell maturation antigen–directed CAR T-cell therapy

por Little, Jessica S., Tandon, Megha, Hong, Joseph Seungpyo, Nadeem, Omar, Sperling, Adam S., Raje, Noopur, Munshi, Nikhil, Frigault, Matthew, Barmettler, Sara, Hammond, Sarah P.
Publicado 2023

Widespread intronic polyadenylation diversifies immune cell transcriptomes

por Singh, Irtisha, Lee, Shih-Han, Sperling, Adam S., Samur, Mehmet K., Tai, Yu-Tzu, Fulciniti, Mariateresa, Munshi, Nikhil C., Mayr, Christine, Leslie, Christina S.
Publicado 2018

A deep molecular response of splenic marginal zone lymphoma to front-line checkpoint blockade

por Miller, Peter G., Sperling, Adam S., Gibson, Christopher J., Pozdnyakova, Olga, Wong, Waihay J., Manos, Michael P., Buchbinder, Elizabeth I., Hodi, F. Stephen, Ebert, Benjamin L., Davids, Matthew S.
Publicado 2020

Selinexor: Targeting a novel pathway in multiple myeloma

por Mo, Clifton C., Yee, Andrew J., Midha, Shonali, Hartley‐Brown, Monique A., Nadeem, Omar, O'Donnell, Elizabeth K., Bianchi, Giada, Sperling, Adam S., Laubach, Jacob P., Richardson, Paul G.
Publicado 2023

Genetic Identification of a Network of Factors that Functionally Interact with the Nucleosome Remodeling ATPase ISWI

por Burgio, Giosalba, La Rocca, Gaspare, Sala, Anna, Arancio, Walter, Di Gesù, Dario, Collesano, Marianna, Sperling, Adam S., Armstrong, Jennifer A., van Heeringen, Simon J., Logie, Colin, Tamkun, John W., Corona, Davide F. V.
Publicado 2008

Biallelic loss of BCMA as a resistance mechanism to CAR T cell therapy in a patient with multiple myeloma

por Samur, Mehmet Kemal, Fulciniti, Mariateresa, Aktas Samur, Anil, Bazarbachi, Abdul Hamid, Tai, Yu-Tzu, Prabhala, Rao, Alonso, Alejandro, Sperling, Adam S., Campbell, Timothy, Petrocca, Fabio, Hege, Kristen, Kaiser, Shari, Loiseau, Hervé Avet, Anderson, Kenneth C., Munshi, Nikhil C.
Publicado 2021

The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein

por Zou, Charles, Yoon, Hojong, Park, Paul M.C., Patten, J.J., Pellman, Jesse, Carreiro, Jeannie, Tsai, Jonathan M., Li, Yen-Der, Roy Burman, Shourya S., Donovan, Katherine A., Gasser, Jessica, Sperling, Adam S., Nowak, Radosław P., Fischer, Eric S., Davey, Robert A., Ebert, Benjamin L., Słabicki, Mikołaj
Publicado 2023

Clonal hematopoiesis is associated with increased risk of progression of asymptomatic Waldenström macroglobulinemia

por Tahri, Sabrin, Mouhieddine, Tarek H., Redd, Robert, Lampe, Luisa, Nilsson, Katarina I., El-Khoury, Habib, Su, Nang Kham, Nassar, Amin H., Adib, Elio, Bindra, Govind, Abou Alaiwi, Sarah, Trippa, Lorenzo, Steensma, David P., Castillo, Jorge J., Treon, Steven P., Ghobrial, Irene M., Sperling, Adam S.
Publicado 2022

Small molecule-induced polymerization triggers degradation of BCL6

por Słabicki, Mikołaj, Yoon, Hojong, Koeppel, Jonas, Nitsch, Lena, Roy Burman, Shourya S., Di Genua, Cristina, Donovan, Katherine A., Sperling, Adam S., Hunkeler, Moritz, Tsai, Jonathan M., Sharma, Rohan, Guirguis, Andrew, Zou, Charles, Chudasama, Priya, Gasser, Jessica A., Miller, Peter G., Scholl, Claudia, Fröhling, Stefan, Nowak, Radosław P., Fischer, Eric S., Ebert, Benjamin L.
Publicado 2020

Quality of life, psychological distress, and prognostic perceptions in caregivers of patients with multiple myeloma

por O’Donnell, Elizabeth K., Shapiro, Yael N., Yee, Andrew J., Nadeem, Omar, Laubach, Jacob P., Branagan, Andrew R., Anderson, Kenneth C., Mo, Clifton C., Munshi, Nikhil C., Ghobrial, Irene M., Sperling, Adam S., Agyemang, Emerentia A., Burke, Jill N., Harrington, Cynthia C., Hu, Bonnie Y., Richardson, Paul G., Raje, Noopur S., El-Jawahri, Areej
Publicado 2022

A Phase I/II Study of Twice Weekly Ixazomib Plus Pomalidomide and Dexamethasone in Relapsed and Refractory Multiple Myeloma: Results from Phase I Dose Escalation Cohorts

por Nadeem, Omar, Mo, Clifton C, Laubach, Jacob P., Bianchi, Giada, Redd, Robert, Barth, Peter, Bayliss, Trevor J., Sanchorawala, Vaishali, Shune, Leyla, Distaso, Alexandra, Dalton, Virginia, Sperling, Adam S, Amweg, Laura, McKenney, Mary, Colson, Kathleen, Millard, Ella L, Hou, Isabella, Savell, Alexandra, Masone, Kelly, Munshi, Nikhil C., Ghobrial, Irene M., Anderson, Kenneth, Richardson, Paul G.
Publicado 2020

Clonal hematopoiesis of indeterminate potential and risk of death from COVID-19

por Miller, Peter G., Fell, Geoffrey G., Foy, Brody H., Scherer, Allison K., Gibson, Christopher J., Sperling, Adam S., Burugula, Bala B., Nakao, Tetsushi, Uddin, Md M., Warren, Hailey, Bry, Lynn, Pozdnyakova, Olga, Frigault, Matthew J., Bick, Alex G., Neuberg, Donna, Higgins, John M., Mansour, Michael K., Natarajan, Pradeep, Kim, Annette S., Kitzman, Jacob O., Ebert, Benjamin L.
Publicado 2022

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K

por Słabicki, Mikołaj, Kozicka, Zuzanna, Petzold, Georg, Li, Yen-Der, Manojkumar, Manisha, Bunker, Richard, Donovan, Katherine A., Sievers, Quinlan L., Koeppel, Jonas, Suchyta, Dakota, Sperling, Adam S., Fink, Emma C., Gasser, Jessica A., Wang, Li R., Corsello, Steven M., Sellar, Rob S., Jan, Max, Gillingham, Dennis, Scholl, Claudia, Fröhling, Stefan, Golub, Todd R., Fischer, Eric S., Thomä, Nicolas H., Ebert, Benjamin L.
Publicado 2020

Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state

por Miller, Peter G., Sathappa, Murugappan, Moroco, Jamie A., Jiang, Wei, Qian, Yue, Iqbal, Sumaiya, Guo, Qi, Giacomelli, Andrew O., Shaw, Subrata, Vernier, Camille, Bajrami, Besnik, Yang, Xiaoping, Raffier, Cerise, Sperling, Adam S., Gibson, Christopher J., Kahn, Josephine, Jin, Cyrus, Ranaghan, Matthew, Caliman, Alisha, Brousseau, Merissa, Fischer, Eric S., Lintner, Robert, Piccioni, Federica, Campbell, Arthur J., Root, David E., Garvie, Colin W., Ebert, Benjamin L.
Publicado 2022

Lenalidomide promotes the development of TP53-mutated therapy-related myeloid neoplasms

por Sperling, Adam S., Guerra, Veronica A., Kennedy, James A., Yan, Yuanqing, Hsu, Joanne I., Wang, Feng, Nguyen, Andrew T., Miller, Peter G., McConkey, Marie E., Quevedo Barrios, Vanessa A., Furudate, Ken, Zhang, Linda, Kanagal-Shamanna, Rashmi, Zhang, Jianhua, Little, Latasha, Gumbs, Curtis, Daver, Naval, DiNardo, Courtney D., Kadia, Tapan, Ravandi, Farhad, Kantarjian, Hagop, Garcia-Manero, Guillermo, Futreal, P. Andrew, Ebert, Benjamin L., Takahashi, Koichi
Publicado 2022

Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells

por Sellar, Rob S., Sperling, Adam S., Słabicki, Mikołaj, Gasser, Jessica A., McConkey, Marie E., Donovan, Katherine A., Mageed, Nada, Adams, Dylan N., Zou, Charles, Miller, Peter G., Dutta, Ravi K., Boettcher, Steffen, Lin, Amy E., Sandoval, Brittany, Quevedo Barrios, Vanessa A., Kovalcik, Veronica, Koeppel, Jonas, Henderson, Elizabeth K., Fink, Emma C., Yang, Lu, Chan, Anthony, Pokharel, Sheela Pangeni, Bergstrom, Erik J., Burt, Rajan, Udeshi, Namrata D., Carr, Steven A., Fischer, Eric S., Chen, Chun-Wei, Ebert, Benjamin L.
Publicado 2022

Functional dissection of inherited non-coding variation influencing multiple myeloma risk

por Ajore, Ram, Niroula, Abhishek, Pertesi, Maroulio, Cafaro, Caterina, Thodberg, Malte, Went, Molly, Bao, Erik L., Duran-Lozano, Laura, Lopez de Lapuente Portilla, Aitzkoa, Olafsdottir, Thorunn, Ugidos-Damboriena, Nerea, Magnusson, Olafur, Samur, Mehmet, Lareau, Caleb A., Halldorsson, Gisli H., Thorleifsson, Gudmar, Norddahl, Gudmundur L., Gunnarsdottir, Kristbjorg, Försti, Asta, Goldschmidt, Hartmut, Hemminki, Kari, van Rhee, Frits, Kimber, Scott, Sperling, Adam S., Kaiser, Martin, Anderson, Kenneth, Jonsdottir, Ingileif, Munshi, Nikhil, Rafnar, Thorunn, Waage, Anders, Weinhold, Niels, Thorsteinsdottir, Unnur, Sankaran, Vijay G., Stefansson, Kari, Houlston, Richard, Nilsson, Björn
Publicado 2022

Author Correction: Functional dissection of inherited non-coding variation influencing multiple myeloma risk

por Ajore, Ram, Niroula, Abhishek, Pertesi, Maroulio, Cafaro, Caterina, Thodberg, Malte, Went, Molly, Bao, Erik L., Duran-Lozano, Laura, Lopez de Lapuente Portilla, Aitzkoa, Olafsdottir, Thorunn, Ugidos-Damboriena, Nerea, Magnusson, Olafur, Samur, Mehmet, Lareau, Caleb A., Halldorsson, Gisli H., Thorleifsson, Gudmar, Norddahl, Gudmundur L., Gunnarsdottir, Kristbjorg, Försti, Asta, Goldschmidt, Hartmut, Hemminki, Kari, van Rhee, Frits, Kimber, Scott, Sperling, Adam S., Kaiser, Martin, Anderson, Kenneth, Jonsdottir, Ingileif, Munshi, Nikhil, Rafnar, Thorunn, Waage, Anders, Weinhold, Niels, Thorsteinsdottir, Unnur, Sankaran, Vijay G., Stefansson, Kari, Houlston, Richard, Nilsson, Björn
Publicado 2022

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

por Bolli, Niccolo, Avet-Loiseau, Hervé, Wedge, David C., Van Loo, Peter, Alexandrov, Ludmil B., Martincorena, Inigo, Dawson, Kevin J., Iorio, Francesco, Nik-Zainal, Serena, Bignell, Graham R., Hinton, Jonathan W., Li, Yilong, Tubio, Jose M.C., McLaren, Stuart, O' Meara, Sarah, Butler, Adam P., Teague, Jon W., Mudie, Laura, Anderson, Elizabeth, Rashid, Naim, Tai, Yu-Tzu, Shammas, Masood A., Sperling, Adam S., Fulciniti, Mariateresa, Richardson, Paul G., Parmigiani, Giovanni, Magrangeas, Florence, Minvielle, Stephane, Moreau, Philippe, Attal, Michel, Facon, Thierry, Futreal, P Andrew, Anderson, Kenneth C., Campbell, Peter J., Munshi, Nikhil C.
Publicado 2014

Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant

por Mouhieddine, Tarek H., Sperling, Adam S., Redd, Robert, Park, Jihye, Leventhal, Matthew, Gibson, Christopher J., Manier, Salomon, Nassar, Amin H., Capelletti, Marzia, Huynh, Daisy, Bustoros, Mark, Sklavenitis-Pistofidis, Romanos, Tahri, Sabrin, Hornburg, Kalvis, Dumke, Henry, Itani, Muhieddine M., Boehner, Cody J., Liu, Chia-Jen, AlDubayan, Saud H., Reardon, Brendan, Van Allen, Eliezer M., Keats, Jonathan J., Stewart, Chip, Mehr, Shaadi, Auclair, Daniel, Schlossman, Robert L., Munshi, Nikhil C., Anderson, Kenneth C., Steensma, David P., Laubach, Jacob P., Richardson, Paul G., Ritz, Jerome, Ebert, Benjamin L., Soiffer, Robert J., Trippa, Lorenzo, Getz, Gad, Neuberg, Donna S., Ghobrial, Irene M.
Publicado 2020