Cytotoxic Chemotherapy as an Immune Stimulus: A Molecular Perspective on Turning Up the Immunological Heat on Cancer

por Opzoomer, James W., Sosnowska, Dominika, Anstee, Joanne E., Spicer, James F., Arnold, James N.
Publicado 2019

Therapeutic targets and new directions for antibodies developed for ovarian cancer

por Bax, Heather J., Josephs, Debra H., Pellizzari, Giulia, Spicer, James F., Montes, Ana, Karagiannis, Sophia N.
Publicado 2016

Beta-glucan contamination of pharmaceutical products: How much should we accept?

por Barton, Claire, Vigor, Kim, Scott, Robert, Jones, Paul, Lentfer, Heike, Bax, Heather J., Josephs, Debra H., Karagiannis, Sophia N., Spicer, James F.
Publicado 2016

Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types

por Ilieva, Kristina M., Cheung, Anthony, Mele, Silvia, Chiaruttini, Giulia, Crescioli, Silvia, Griffin, Merope, Nakamura, Mano, Spicer, James F., Tsoka, Sophia, Lacy, Katie E., Tutt, Andrew N. J., Karagiannis, Sophia N.
Publicado 2018

Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs)

por Hoffmann, Ricarda M., Coumbe, Ben G. T., Josephs, Debra H., Mele, Silvia, Ilieva, Kristina M., Cheung, Anthony, Tutt, Andrew N., Spicer, James F., Thurston, David E., Crescioli, Silvia, Karagiannis, Sophia N.
Publicado 2017

IgE Antibodies against Cancer: Efficacy and Safety

por Chauhan, Jitesh, McCraw, Alex J., Nakamura, Mano, Osborn, Gabriel, Sow, Heng Sheng, Cox, Vivienne F., Stavraka, Chara, Josephs, Debra H., Spicer, James F., Karagiannis, Sophia N., Bax, Heather J.
Publicado 2020

Evaluation of Antigen-Conjugated Fluorescent Beads to Identify Antigen-Specific B Cells

por Correa, Isabel, Ilieva, Kristina M., Crescioli, Silvia, Lombardi, Sara, Figini, Mariangela, Cheung, Anthony, Spicer, James F., Tutt, Andrew N. J., Nestle, Frank O., Karagiannis, Panagiotis, Lacy, Katie E., Karagiannis, Sophia N.
Publicado 2018

A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma

por Hoffmann, Ricarda M., Crescioli, Silvia, Mele, Silvia, Sachouli, Eirini, Cheung, Anthony, Chui, Connie K., Andriollo, Paolo, Jackson, Paul J. M., Lacy, Katie E., Spicer, James F., Thurston, David E., Karagiannis, Sophia N.
Publicado 2020

In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model

por Williams, Iwan P., Crescioli, Silvia, Sow, Heng Sheng, Bax, Heather J., Hobbs, Carl, Ilieva, Kristina M., French, Elise, Pellizzari, Giulia, Cox, Vivienne, Josephs, Debra H., Spicer, James F., Karagiannis, Sophia N., Mele, Silvia
Publicado 2019

Targeting folate receptor alpha for cancer treatment

por Cheung, Anthony, Bax, Heather J., Josephs, Debra H., Ilieva, Kristina M., Pellizzari, Giulia, Opzoomer, James, Bloomfield, Jacinta, Fittall, Matthew, Grigoriadis, Anita, Figini, Mariangela, Canevari, Silvana, Spicer, James F., Tutt, Andrew N., Karagiannis, Sophia N.
Publicado 2016

Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology

por Crescioli, Silvia, Chiaruttini, Giulia, Mele, Silvia, Ilieva, Kristina M., Pellizzari, Giulia, Spencer, Daniel I.R., Gardner, Richard A., Lacy, Katie E., Spicer, James F., Tutt, Andrew N.J., Wagner, Gerd K., Karagiannis, Sophia N.
Publicado 2018

IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states

por Pellizzari, Giulia, Hoskin, Coran, Crescioli, Silvia, Mele, Silvia, Gotovina, Jelena, Chiaruttini, Giulia, Bianchini, Rodolfo, Ilieva, Kristina, Bax, Heather J., Papa, Sophie, Lacy, Katie E., Jensen-Jarolim, Erika, Tsoka, Sophia, Josephs, Debra H., Spicer, James F., Karagiannis, Sophia N.
Publicado 2019

AllergoOncology: Expression platform development and functional profiling of an anti‐HER2 IgE antibody

por Ilieva, Kristina M., Fazekas‐Singer, Judit, Bax, Heather J., Crescioli, Silvia, Montero‐Morales, Laura, Mele, Silvia, Sow, Heng Sheng, Stavraka, Chara, Josephs, Debra H., Spicer, James F., Steinkellner, Herta, Jensen‐Jarolim, Erika, Tutt, Andrew N. J., Karagiannis, Sophia N.
Publicado 2019

BRAF inhibitors: resistance and the promise of combination treatments for melanoma

por Griffin, Merope, Scotto, Daniele, Josephs, Debra H., Mele, Silvia, Crescioli, Silvia, Bax, Heather J., Pellizzari, Giulia, Wynne, Matthew D., Nakamura, Mano, Hoffmann, Ricarda M., Ilieva, Kristina M., Cheung, Anthony, Spicer, James F., Papa, Sophie, Lacy, Katie E., Karagiannis, Sophia N.
Publicado 2017

Immune mediator expression signatures are associated with improved outcome in ovarian carcinoma

por Nakamura, Mano, Bax, Heather J., Scotto, Daniele, Souri, Elmira Amiri, Sollie, Sam, Harris, Robert J., Hammar, Niklas, Walldius, Goran, Winship, Anna, Ghosh, Sharmistha, Montes, Ana, Spicer, James F., Van Hemelrijck, Mieke, Josephs, Debra H., Lacy, Katie E., Tsoka, Sophia, Karagiannis, Sophia N.
Publicado 2019

Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs)

por Hoffmann, Ricarda M., Mele, Silvia, Cheung, Anthony, Larcombe-Young, Daniel, Bucaite, Gintare, Sachouli, Eirini, Zlatareva, Iva, Morad, Hassan O. J., Marlow, Rebecca, McDonnell, James M., Figini, Mariangela, Lacy, Katie E., Tutt, Andrew J. N., Spicer, James F., Thurston, David E., Karagiannis, Sophia N., Crescioli, Silvia
Publicado 2020

IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype

por Nakamura, Mano, Souri, Elmira Amiri, Osborn, Gabriel, Laddach, Roman, Chauhan, Jitesh, Stavraka, Chara, Lombardi, Sara, Black, Anna, Khiabany, Atousa, Khair, Duaa O., Figini, Mariangela, Winship, Anna, Ghosh, Sharmistha, Montes, Ana, Spicer, James F., Bax, Heather J., Josephs, Debra H., Lacy, Katie E., Tsoka, Sophia, Karagiannis, Sophia N.
Publicado 2020

Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma

por Karagiannis, Panagiotis, Villanova, Federica, Josephs, Debra H, Correa, Isabel, Van Hemelrijck, Mieke, Hobbs, Carl, Saul, Louise, Egbuniwe, Isioma U, Tosi, Isabella, Ilieva, Kristina M, Kent, Emma, Calonje, Eduardo, Harries, Mark, Fentiman, Ian, Taylor-Papadimitriou, Joyce, Burchell, Joy, Spicer, James F, Lacy, Katie E, Nestle, Frank O, Karagiannis, Sophia N
Publicado 2015

Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields

por Ilieva, Kristina M., Fazekas-Singer, Judit, Achkova, Daniela Y., Dodev, Tihomir S., Mele, Silvia, Crescioli, Silvia, Bax, Heather J., Cheung, Anthony, Karagiannis, Panagiotis, Correa, Isabel, Figini, Mariangela, Marlow, Rebecca, Josephs, Debra H., Beavil, Andrew J., Maher, John, Spicer, James F., Jensen-Jarolim, Erika, Tutt, Andrew N., Karagiannis, Sophia N.
Publicado 2017

Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome

por Bax, Heather J., Chauhan, Jitesh, Stavraka, Chara, Khiabany, Atousa, Nakamura, Mano, Pellizzari, Giulia, Ilieva, Kristina M., Lombardi, Sara, Gould, Hannah J., Corrigan, Christopher J., Till, Stephen J., Katugampola, Sidath, Jones, Paul S., Barton, Claire, Winship, Anna, Ghosh, Sharmistha, Montes, Ana, Josephs, Debra H., Spicer, James F., Karagiannis, Sophia N.
Publicado 2020