Use of Synthetic Isoprenoids to Target Protein Prenylation and Rho GTPases in Breast Cancer Invasion

por Chen, Min, Knifley, Teresa, Subramanian, Thangaiah, Spielmann, H. Peter, O’Connor, Kathleen L.
Publicado 2014

Assessing the efficacy of protein farnesyltransferase inhibitors in mouse models of progeria

por Yang, Shao H., Chang, Sandy Y., Andres, Douglas A., Spielmann, H. Peter, Young, Stephen G., Fong, Loren G.
Publicado 2010

Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors

por Holland, Andrew J., Reis, Rita M., Niessen, Sherry, Pereira, Cláudia, Andres, Douglas A., Spielmann, H. Peter, Cleveland, Don W., Desai, Arshad, Gassmann, Reto
Publicado 2015

Structure and Specificity of a Permissive Bacterial C-Prenyltransferase

por Elshahawi, Sherif I., Cao, Hongnan, Shaaban, Khaled A., Ponomareva, Larissa V., Subramanian, Thangaiah, Farman, Mark L., Spielmann, H. Peter, Phillips, George N., Thorson, Jon S., Singh, Shanteri
Publicado 2017

Activating the synthesis of progerin, the mutant prelamin A in Hutchinson–Gilford progeria syndrome, with antisense oligonucleotides

por Fong, Loren G., Vickers, Timothy A., Farber, Emily A., Choi, Christine, Yun, Ui Jeong, Hu, Yan, Yang, Shao H., Coffinier, Catherine, Lee, Roger, Yin, Liya, Davies, Brandon S.J., Andres, Douglas A., Spielmann, H. Peter, Bennett, C. Frank, Young, Stephen G.
Publicado 2009