Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity

por Wahl, Geoffrey M., Spike, Benjamin T.
Publicado 2017

Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy

por Pfefferle, Adam D., Spike, Benjamin T., Wahl, Geoff M., Perou, Charles M.
Publicado 2015

Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis

por Trejo, Christy L., Luna, Gidsela, Dravis, Christopher, Spike, Benjamin T., Wahl, Geoffrey M.
Publicado 2017

Differential requirement of GRP94 and GRP78 in mammary gland development

por Zhu, Genyuan, Wang, Miao, Spike, Benjamin, Gray, Peter C., Shen, Jieli, Lee, Sung-Hyung, Chen, Si-Yi, Lee, Amy S.
Publicado 2014

Whence CRIPTO: The Reemergence of an Oncofetal Factor in ‘Wounds’ That Fail to Heal

por Freeman, David W., Rodrigues Sousa, Elisa, Karkampouna, Sofia, Zoni, Eugenio, Gray, Peter C., Salomon, David S., Kruithof-de Julio, Marianna, Spike, Benjamin T.
Publicado 2021

Progesterone receptor antagonists reverse stem cell expansion and the paracrine effectors of progesterone action in the mouse mammary gland

por Ranjan, Manish, Lee, Oukseub, Cottone, Gannon, Mirzaei Mehrabad, Elnaz, Spike, Benjamin T., Zeng, Zexian, Yadav, Shivangi, Chatterton, Robert, Kim, J. Julie, Clare, Susan E., Khan, Seema A.
Publicado 2021

Multiparametric quantitative phase imaging for real-time, single cell, drug screening in breast cancer

por Polanco, Edward R., Moustafa, Tarek E., Butterfield, Andrew, Scherer, Sandra D., Cortes-Sanchez, Emilio, Bodily, Tyler, Spike, Benjamin T., Welm, Bryan E., Bernard, Philip S., Zangle, Thomas A.
Publicado 2022

CRIPTO/GRP78 Signaling Maintains Fetal and Adult Mammary Stem Cells Ex Vivo

por Spike, Benjamin T., Kelber, Jonathan A., Booker, Evan, Kalathur, Madhuri, Rodewald, Rose, Lipianskaya, Julia, La, Justin, He, Marielle, Wright, Tracy, Klemke, Richard, Wahl, Geoffrey M., Gray, Peter C.
Publicado 2014

An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma

por Zewdu, Rediet, Mehrabad, Elnaz Mirzaei, Ingram, Kelley, Fang, Pengshu, Gillis, Katherine L, Camolotto, Soledad A, Orstad, Grace, Jones, Alex, Mendoza, Michelle C, Spike, Benjamin T, Snyder, Eric L
Publicado 2021

Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool

por Jiao, Xuanmao, Li, Zhiping, Wang, Min, Katiyar, Sanjay, Di Sante, Gabriele, Farshchian, Mehdi, South, Andrew P., Cocola, Cinzia, Colombo, Daniele, Reinbold, Rolland, Zucchi, Ileana, Wu, Kongming, Tabas, Ira, Spike, Benjamin T., Pestell, Richard G.
Publicado 2018

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts

por Pfefferle, Adam D, Herschkowitz, Jason I, Usary, Jerry, Harrell, Joshua Chuck, Spike, Benjamin T, Adams, Jessica R, Torres-Arzayus, Maria I, Brown, Myles, Egan, Sean E, Wahl, Geoffrey M, Rosen, Jeffrey M, Perou, Charles M
Publicado 2013

CRIPTO antagonist ALK4(L75A)-Fc inhibits breast cancer cell plasticity and adaptation to stress

por Balcioglu, Ozlen, Heinz, Richard E., Freeman, David W., Gates, Brooke L., Hagos, Berhane M., Booker, Evan, Mirzaei Mehrabad, Elnaz, Diesen, Hyrum T., Bhakta, Kishan, Ranganathan, Supraja, Kachi, Masami, Leblanc, Mathias, Gray, Peter C., Spike, Benjamin T.
Publicado 2020

Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy

por Saison-Ridinger, Maya, DelGiorno, Kathleen E., Zhang, Tejia, Kraus, Annabelle, French, Randall, Jaquish, Dawn, Tsui, Crystal, Erikson, Galina, Spike, Benjamin T., Shokhirev, Maxim N., Liddle, Christopher, Yu, Ruth T., Downes, Michael, Evans, Ronald M., Saghatelian, Alan, Lowy, Andrew M., Wahl, Geoffrey M.
Publicado 2017

Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland Development

por Giraddi, Rajshekhar R., Chung, Chi-Yeh, Heinz, Richard E., Balcioglu, Ozlen, Novotny, Mark, Trejo, Christy L., Dravis, Christopher, Hagos, Berhane M., Mehrabad, Elnaz Mirzaei, Rodewald, Luo Wei, Hwang, Jae Y., Fan, Cheng, Lasken, Roger, Varley, Katherine E., Perou, Charles M., Wahl, Geoffrey M., Spike, Benjamin T.
Publicado 2018