Peptidome Surveillance Across Evolving SARS-CoV-2 Lineages Reveals HLA Binding Conservation in Nucleocapsid Among Variants With Most Potential for T-Cell Epitope Loss in Spike

por Wnuk, Kamil, Sudol, Jeremi, Spilman, Patricia, Soon-Shiong, Patrick
Publicado 2022

Complete response to avelumab and IL-15 superagonist N-803 with Abraxane in Merkel cell carcinoma: a case study

por Drusbosky, Leylah, Nangia, Chaitali, Nguyen, Andrew, Szeto, Christopher, Newton, Yulia, Spilman, Patricia, Reddy, Sandeep Bobby
Publicado 2020

Deformable Nanovesicles Synthesized through an Adaptable Microfluidic Platform for Enhanced Localized Transdermal Drug Delivery

por Subbiah, Naren, Campagna, Jesus, Spilman, Patricia, Alam, Mohammad Parvez, Sharma, Shivani, Hokugo, Akishige, Nishimura, Ichiro, John, Varghese
Publicado 2017

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

por Spilman, Patricia, Podlutskaya, Natalia, Hart, Matthew J., Debnath, Jayanta, Gorostiza, Olivia, Bredesen, Dale, Richardson, Arlan, Strong, Randy, Galvan, Veronica
Publicado 2010

Correction: Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

por Spilman, Patricia, Podlutskaya, Natalia, Hart, Matthew J., Debnath, Jayanta, Gorostiza, Olivia, Bredesen, Dale, Richardson, Arlan, Strong, Randy, Galvan, Veronica
Publicado 2011

Correction: Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

por Spilman, Patricia, Podlutskaya, Natalia, Hart, Matthew J., Debnath, Jayanta, Gorostiza, Olivia, Bredesen, Dale, Richardson, Arlan, Strong, Randy, Galvan, Veronica
Publicado 2011

Screening for Small Molecule Inhibitors of Statin-Induced APP C-terminal Toxic Fragment Production

por Poksay, Karen S., Sheffler, Douglas J., Spilman, Patricia, Campagna, Jesus, Jagodzinska, Barbara, Descamps, Olivier, Gorostiza, Olivia, Matalis, Alex, Mullenix, Michael, Bredesen, Dale E., Cosford, Nicholas D. P., John, Varghese
Publicado 2017

Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson’s disease model

por Zhu, Chunni, Bilousova, Tina, Focht, Samantha, Jun, Michael, Elias, Chris Jean, Melnik, Mikhail, Chandra, Sujyoti, Campagna, Jesus, Cohn, Whitaker, Hatami, Asa, Spilman, Patricia, Gylys, Karen Hoppens, John, Varghese
Publicado 2021

Correction to: Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson’s disease model

por Zhu, Chunni, Bilousova, Tina, Focht, Samantha, Jun, Michael, Elias, Chris Jean, Melnik, Mikhail, Chandra, Sujyoti, Campagna, Jesus, Cohn, Whitaker, Hatami, Asa, Spilman, Patricia, Gylys, Karen Hoppens, John, Varghese
Publicado 2021

Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue

por Cohn, Whitaker, Zhu, Chunni, Campagna, Jesus, Bilousova, Tina, Spilman, Patricia, Teter, Bruce, Li, Feng, Guo, Rong, Elashoff, David, Cole, Greg M., Avidan, Alon, Faull, Kym Francis, Whitelegge, Julian, Wong, David T. W., John, Varghese
Publicado 2022

An ACE2 Triple Decoy that neutralizes SARS-CoV-2 shows enhanced affinity for virus variants

por Tanaka, Shiho, Nelson, Gard, Olson, C. Anders, Buzko, Oleksandr, Higashide, Wendy, Shin, Annie, Gonzalez, Marcos, Taft, Justin, Patel, Roosheel, Buta, Sofija, Richardson, Ashley, Bogunovic, Dusan, Spilman, Patricia, Niazi, Kayvan, Rabizadeh, Shahrooz, Soon-Shiong, Patrick
Publicado 2021

A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer’s disease mouse model

por Campagna, Jesus, Spilman, Patricia, Jagodzinska, Barbara, Bai, Dongsheng, Hatami, Asa, Zhu, Chunni, Bilousova, Tina, Jun, Michael, Elias, Chris Jean, Pham, Johnny, Cole, Gregory, LaDu, Mary Jo, Jung, Michael E., Bredesen, Dale E., John, Varghese
Publicado 2018

Graphene nanoplatelet and graphene oxide functionalization of face mask materials inhibits infectivity of trapped SARS-CoV-2

por De Maio, Flavio, Palmieri, Valentina, Babini, Gabriele, Augello, Alberto, Palucci, Ivana, Perini, Giordano, Salustri, Alessandro, Spilman, Patricia, De Spirito, Marco, Sanguinetti, Maurizio, Delogu, Giovanni, Rizzi, Laura Giorgia, Cesareo, Giulio, Soon-Shiong, Patrick, Sali, Michela, Papi, Massimiliano
Publicado 2021

Heterologous saRNA Prime, DNA Dual-Antigen Boost SARS-CoV-2 Vaccination Elicits Robust Cellular Immunogenicity and Cross-Variant Neutralizing Antibodies

por Rice, Adrian, Verma, Mohit, Voigt, Emily, Battisti, Peter, Beaver, Sam, Reed, Sierra, Dinkins, Kyle, Mody, Shivani, Zakin, Lise, Tanaka, Shiho, Morimoto, Brett, Olson, C. Anders, Gabitzsch, Elizabeth, Safrit, Jeffrey T., Spilman, Patricia, Casper, Corey, Soon-Shiong, Patrick
Publicado 2022

Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display

por Tanaka, Shiho, Olson, C. Anders, Barnes, Christopher O., Higashide, Wendy, Gonzalez, Marcos, Taft, Justin, Richardson, Ashley, Martin-Fernandez, Marta, Bogunovic, Dusan, Gnanapragasam, Priyanthi N.P., Bjorkman, Pamela J., Spilman, Patricia, Niazi, Kayvan, Rabizadeh, Shahrooz, Soon-Shiong, Patrick
Publicado 2022

Intranasal plus subcutaneous prime vaccination with a dual antigen COVID-19 vaccine elicits T-cell and antibody responses in mice

por Rice, Adrian, Verma, Mohit, Shin, Annie, Zakin, Lise, Sieling, Peter, Tanaka, Shiho, Balint, Joseph, Dinkins, Kyle, Adisetiyo, Helty, Morimoto, Brett, Higashide, Wendy, Anders Olson, C., Mody, Shivani, Spilman, Patricia, Gabitzsch, Elizabeth, Safrit, Jeffrey T., Rabizadeh, Shahrooz, Niazi, Kayvan, Soon-Shiong, Patrick
Publicado 2021

Inferred Immune-Cell Activity Is an Independent Predictor of HER2-Negative Breast Cancer Prognosis and Response to Paclitaxel-Based Therapy in the GeparSepto Trial

por Fasching, Peter A., Szeto, Christopher, Denkert, Carsten, Benz, Stephen, Weber, Karsten, Spilman, Patricia, Budczies, Jan, Schneeweiss, Andreas, Stickeler, Elmar, Schmatloch, Sabine, Jackisch, Christian, Karn, Thomas, Sinn, Hans Peter, Warm, Mathias, van Mackelenbergh, Marion, Rabizadeh, Shahrooz, Schem, Christian, Heinmöller, Ernst, Mueller, Volkmar, Marmé, Frederik, Soon-Shiong, Patrick, Nekljudova, Valentina, Untch, Michael, Loibl, Sibylle
Publicado 2023

Dual-Antigen COVID-19 Vaccine Subcutaneous Prime Delivery With Oral Boosts Protects NHP Against SARS-CoV-2 Challenge

por Gabitzsch, Elizabeth, Safrit, Jeffrey T., Verma, Mohit, Rice, Adrian, Sieling, Peter, Zakin, Lise, Shin, Annie, Morimoto, Brett, Adisetiyo, Helty, Wong, Raymond, Bezawada, Ashish, Dinkins, Kyle, Balint, Joseph, Peykov, Victor, Garban, Hermes, Liu, Philip, Bacon, Andrew, Bone, Pete, Drew, Jeff, Sanford, Daniel C., Spilman, Patricia, Sender, Lennie, Rabizadeh, Shahrooz, Niazi, Kayvan, Soon-Shiong, Patrick
Publicado 2021

Identification and validation of expressed HLA-binding breast cancer neoepitopes for potential use in individualized cancer therapy

por Reimann, Hannah, Nguyen, Andrew, Sanborn, J Zachary, Vaske, Charles J, Benz, Stephen C, Niazi, Kayvan, Rabizadeh, Shahrooz, Spilman, Patricia, Mackensen, Andreas, Ruebner, Matthias, Hein, Alexander, Beckmann, Matthias W, van der Meijden, Edith D, Bausenwein, Judith, Kretschmann, Sascha, Griffioen, Marieke, Schlom, Jeffrey, Gulley, James L, Lee, Karin L, Hamilton, Duane H, Soon-Shiong, Patrick, Fasching, Peter A, Kremer, Anita N.
Publicado 2021

Safety, Feasibility, and Merits of Longitudinal Molecular Testing of Multiple Metastatic Sites to Inform mTNBC Patient Treatment in the Intensive Trial of Omics in Cancer

por Burton, Kimberly A., Mahen, Elisabeth, Konnick, Eric Quentin, Blau, Sibel, Dorschner, Michael O., Ramirez, Arturo B., Schmechel, Stephen C., Song, Chaozhong, Parulkar, Rahul, Parker, Stephanie, Senecal, Francis Mark, Pritchard, Colin C., Mecham, Brigham H., Szeto, Christopher, Spilman, Patricia, Zhu, Jingchun, Gadi, Vijayakrishna K., Ronen, Roy, Stilwell, Jackie, Kaldjian, Eric, Dutkowski, Janusz, Benz, Stephen Charles, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Blau, C. Anthony
Publicado 2022