Neuroimaging in Frontotemporal Dementia: Heterogeneity and Relationships with Underlying Neuropathology

por Peet, Bradley T., Spina, Salvatore, Mundada, Nidhi, La Joie, Renaud
Publicado 2021

The tauopathy associated with mutation +3 in intron 10 of Tau: characterization of the MSTD family

por Spina, Salvatore, Farlow, Martin R., Unverzagt, Frederick W., Kareken, David A., Murrell, Jill R., Fraser, Graham, Epperson, Francine, Crowther, R. Anthony, Spillantini, Maria G., Goedert, Michel, Ghetti, Bernardino
Publicado 2008

Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer’s disease

por Rimal, Suman, Li, Yu, Vartak, Rasika, Geng, Ji, Tantray, Ishaq, Li, Shuangxi, Huh, Sungun, Vogel, Hannes, Glabe, Charles, Grinberg, Lea T., Spina, Salvatore, Seeley, William W., Guo, Su, Lu, Bingwei
Publicado 2021

Advancing functional dysconnectivity and atrophy in progressive supranuclear palsy

por Brown, Jesse A., Hua, Alice Y., Trujillo, Andrew, Attygalle, Suneth, Binney, Richard J., Spina, Salvatore, Lee, Suzee E., Kramer, Joel H., Miller, Bruce L., Rosen, Howard J., Boxer, Adam L., Seeley, William W.
Publicado 2017

Elevated levels of extracellular vesicles in progranulin‐deficient mice and FTD‐GRN Patients

por Arrant, Andrew E., Davis, Skylar E., Vollmer, Rachael M., Murchison, Charles F., Mobley, James A., Nana, Alissa L., Spina, Salvatore, Grinberg, Lea T., Karydas, Anna M., Miller, Bruce L., Seeley, William W., Roberson, Erik D.
Publicado 2020

Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling

por Minaya, Miguel A., Mahali, Sidhartha, Iyer, Abhirami K., Eteleeb, Abdallah M., Martinez, Rita, Huang, Guangming, Budde, John, Temple, Sally, Nana, Alissa L., Seeley, William W., Spina, Salvatore, Grinberg, Lea T., Harari, Oscar, Karch, Celeste M.
Publicado 2023

Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations

por Maarouf, Chera L, Daugs, Ian D, Spina, Salvatore, Vidal, Ruben, Kokjohn, Tyler A, Patton, R Lyle, Kalback, Walter M, Luehrs, Dean C, Walker, Douglas G, Castaño, Eduardo M, Beach, Thomas G, Ghetti, Bernardino, Roher, Alex E
Publicado 2008

Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations

por Arrant, Andrew E., Roth, Jonathan R., Boyle, Nicholas R., Kashyap, Shreya N., Hoffmann, Madelyn Q., Murchison, Charles F., Ramos, Eliana Marisa, Nana, Alissa L., Spina, Salvatore, Grinberg, Lea T., Miller, Bruce L., Seeley, William W., Roberson, Erik D.
Publicado 2019

Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants

por Lin, Li-Chun, Nana, Alissa L., Hepker, Mackenzie, Hwang, Ji-Hye Lee, Gaus, Stephanie E., Spina, Salvatore, Cosme, Celica G., Gan, Li, Grinberg, Lea T., Geschwind, Daniel H., Coppola, Giovanni, Rosen, Howard J., Miller, Bruce L., Seeley, William W.
Publicado 2019

Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia

por Miller, Zachary A, Spina, Salvatore, Pakvasa, Mikhail, Rosenberg, Lynne, Watson, Christa, Mandelli, Maria Luisa, Paredes, Mercedes F, Joie, Renaud La, Rabinovici, Gil D, Rosen, Howard J, Grinberg, Lea T, Huang, Eric J, Miller, Bruce L, Seeley, William W, Gorno-Tempini, Maria Luisa
Publicado 2019

Postmortem Human Dura Mater Cells Exhibit Phenotypic, Transcriptomic and Genetic Abnormalities that Impact their Use for Disease Modeling

por Argouarch, Andrea R., Schultz, Nina, Yang, Andrew C., Jang, Yeongjun, Garcia, Kristle, Cosme, Celica G., Corrales, Christian I., Nana, Alissa L., Karydas, Anna M., Spina, Salvatore, Grinberg, Lea T., Miller, Bruce, Wyss-Coray, Tony, Abyzov, Alexej, Goodarzi, Hani, Seeley, William W., Kao, Aimee W.
Publicado 2022

Neuropsychiatric symptoms and imbalance of atrophy in behavioral variant frontotemporal dementia

por Sokołowski, Andrzej, Roy, Ashlin R. K., Goh, Sheng‐Yang M., Hardy, Emily G., Datta, Samir, Cobigo, Yann, Brown, Jesse A., Spina, Salvatore, Grinberg, Lea, Kramer, Joel, Rankin, Katherine P., Seeley, William W., Sturm, Virginia E., Rosen, Howard J., Miller, Bruce L., Perry, David C.
Publicado 2023

Molecular characterization of selectively vulnerable neurons in Alzheimer’s Disease

por Leng, Kun, Li, Emmy, Eser, Rana, Piergies, Antonia, Sit, Rene, Tan, Michelle, Neff, Norma, Li, Song Hua, Rodriguez, Roberta Diehl, Suemoto, Claudia Kimie, Leite, Renata Elaine Paraizo, Ehrenberg, Alexander J., Pasqualucci, Carlos A., Seeley, William W., Spina, Salvatore, Heinsen, Helmut, Grinberg, Lea T., Kampmann, Martin
Publicado 2021

Detection of emerging neurodegeneration using Bayesian linear mixed-effect modeling

por Cobigo, Yann, Goh, Matthew S., Wolf, Amy, Staffaroni, Adam M., Kornak, John, Miller, Bruce L., Rabinovici, Gil D., Seeley, William W., Spina, Salvatore, Boxer, Adam L., Boeve, Bradley F., Wang, Lei, Allegri, Ricardo, Farlow, Marty, Mori, Hiroshi, Perrin, Richard J., Kramer, Joel, Rosen, Howard J.
Publicado 2022

Frontotemporal dementia presentation in patients with heterozygous p.H157Y variant of TREM2

por Ogonowski, Natalia, Santamaria-Garcia, Hernando, Baez, Sandra, Lopez, Andrea, Laserna, Andrés, Garcia-Cifuentes, Elkin, Ayala-Ramirez, Paola, Zarante, Ignacio, Suarez-Obando, Fernando, Reyes, Pablo, Kauffman, Marcelo, Cochran, Nick, Schulte, Michael, Sirkis, Daniel W, Spina, Salvatore, Yokoyama, Jennifer S, Miller, Bruce L, Kosik, Kenneth S, Matallana, Diana, Ibáñez, Agustín
Publicado 2023

Astroglial toxicity promotes synaptic degeneration in the thalamocortical circuit in frontotemporal dementia with GRN mutations

por Marsan, Elise, Velmeshev, Dmitry, Ramsey, Arren, Patel, Ravi K., Zhang, Jiasheng, Koontz, Mark, Andrews, Madeline G., de Majo, Martina, Mora, Cristina, Blumenfeld, Jessica, Li, Alissa N., Spina, Salvatore, Grinberg, Lea T., Seeley, William W., Miller, Bruce L., Ullian, Erik M., Krummel, Matthew F., Kriegstein, Arnold R., Huang, Eric J.
Publicado 2023

KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss

por Kauwe, Grant, Pareja-Navarro, Kristeen A., Yao, Lei, Chen, Jackson H., Wong, Ivy, Saloner, Rowan, Cifuentes, Helen, Nana, Alissa L., Shah, Samah, Li, Yaqiao, Le, David, Spina, Salvatore, Grinberg, Lea T., Seeley, William W., Kramer, Joel H., Sacktor, Todd C., Schilling, Birgit, Gan, Li, Casaletto, Kaitlin B., Tracy, Tara E.
Publicado 2023

Cerebrospinal Fluid Biomarkers in Autopsy-Confirmed Alzheimer Disease and Frontotemporal Lobar Degeneration

por Mattsson-Carlgren, Niklas, Grinberg, Lea T., Boxer, Adam, Ossenkoppele, Rik, Jonsson, Magnus, Seeley, William, Ehrenberg, Alexander, Spina, Salvatore, Janelidze, Shorena, Rojas-Martinex, Julio, Rosen, Howard, La Joie, Renaud, Lesman-Segev, Orit, Iaccarino, Leonardo, Kollmorgen, Gwendlyn, Ljubenkov, Peter, Eichenlaub, Udo, Gorno-Tempini, Maria Luisa, Miller, Bruce, Hansson, Oskar, Rabinovici, Gil Dan
Publicado 2022

Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis

por Boland, Sebastian, Swarup, Sharan, Ambaw, Yohannes A., Malia, Pedro C., Richards, Ruth C., Fischer, Alexander W., Singh, Shubham, Aggarwal, Geetika, Spina, Salvatore, Nana, Alissa L., Grinberg, Lea T., Seeley, William W., Surma, Michal A., Klose, Christian, Paulo, Joao A., Nguyen, Andrew D., Harper, J. Wade, Walther, Tobias C., Farese, Robert V.
Publicado 2022

Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory

por Ljubenkov, Peter A., Staffaroni, Adam M., Rojas, Julio C., Allen, Isabel E., Wang, Ping, Heuer, Hilary, Karydas, Anna, Kornak, John, Cobigo, Yann, Seeley, William W., Grinberg, Lea T., Spina, Salvatore, Fagan, Anne M., Jerome, Gina, Knopman, David, Boeve, Brad F., Dickerson, Bradford C., Kramer, Joel, Miller, Bruce, Boxer, Adam L., Rosen, Howard J.
Publicado 2018