Reversing the Negative Genomic Effects of Aging with Short-Term Calorie Restriction

por Spindler, Stephen R.
Publicado 2001

Dietary supplementation with Lovaza and krill oil shortens the life span of long-lived F1 mice

por Spindler, Stephen R., Mote, Patricia L., Flegal, James M.
Publicado 2014

Combined statin and angiotensin-converting enzyme (ACE) inhibitor treatment increases the lifespan of long-lived F1 male mice

por Spindler, Stephen R., Mote, Patricia L., Flegal, James M.
Publicado 2016

Novel Protein Kinase Signaling Systems Regulating Lifespan Identified by Small Molecule Library Screening Using Drosophila

por Spindler, Stephen R., Li, Rui, Dhahbi, Joseph M., Yamakawa, Amy, Sauer, Frank
Publicado 2012

Deep Sequencing of Serum Small RNAs Identifies Patterns of 5′ tRNA Half and YRNA Fragment Expression Associated with Breast Cancer

por Dhahbi, Joseph M, Spindler, Stephen R, Atamna, Hani, Boffelli, Dario, Martin, David IK
Publicado 2014

Deep Sequencing Reveals Novel MicroRNAs and Regulation of MicroRNA Expression during Cell Senescence

por Dhahbi, Joseph M., Atamna, Hani, Boffelli, Dario, Magis, Wendy, Spindler, Stephen R., Martin, David I. K.
Publicado 2011

5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction

por Dhahbi, Joseph M, Spindler, Stephen R, Atamna, Hani, Yamakawa, Amy, Boffelli, Dario, Mote, Patricia, Martin, David IK
Publicado 2013

Nordihydroguaiaretic Acid Extends the Lifespan of Drosophila and Mice, Increases Mortality-Related Tumors and Hemorrhagic Diathesis, and Alters Energy Homeostasis in Mice

por Spindler, Stephen R., Mote, Patricia L., Lublin, Alex L., Flegal, James M., Dhahbi, Joseph M., Li, Rui
Publicado 2015

MicroRNAs Circulate in the Hemolymph of Drosophila and Accumulate Relative to Tissue microRNAs in an Age-Dependent Manner

por Dhahbi, Joseph M., Atamna, Hani, Li, Rui, Yamakawa, Amy, Guerrero, Noel, Lam, Hanh T., Mote, Patricia, Spindler, Stephen R.
Publicado 2016

Deep sequencing identifies circulating mouse miRNAs that are functionally implicated in manifestations of aging and responsive to calorie restriction

por Dhahbi, Joseph M, Spindler, Stephen R, Atamna, Hani, Yamakawa, Amy, Guerrero, Noel, Boffelli, Dario, Mote, Patricia, Martin, David IK
Publicado 2013

Circulating microRNA signature of genotype‐by‐age interactions in the long‐lived Ames dwarf mouse

por Victoria, Berta, Dhahbi, Joseph M., Nunez Lopez, Yury O., Spinel, Lina, Atamna, Hani, Spindler, Stephen R., Masternak, Michal M.
Publicado 2015

Statin Treatment Increases Lifespan and Improves Cardiac Health in Drosophila by Decreasing Specific Protein Prenylation

por Spindler, Stephen R., Li, Rui, Dhahbi, Joseph M., Yamakawa, Amy, Mote, Patricia, Bodmer, Rolf, Ocorr, Karen, Williams, Renee T., Wang, Yinsheng, Ablao, Kenneth P.
Publicado 2012

Circulating small non coding RNA signature in head and neck squamous cell carcinoma

por Martinez, Berta Victoria, Dhahbi, Joseph M., Lopez, Yury O. Nunez, Lamperska, Katarzyna, Golusinski, Paweł, Luczewski, Lukasz, Kolenda, Tomasz, Atamna, Hani, Spindler, Stephen R., Golusinski, Wojciech, Masternak, Michal M.
Publicado 2015

Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms

por Schumacher, Björn, van der Pluijm, Ingrid, Moorhouse, Michael J., Kosteas, Theodore, Robinson, Andria Rasile, Suh, Yousin, Breit, Timo M., van Steeg, Harry, Niedernhofer, Laura J., van IJcken, Wilfred, Bartke, Andrzej, Spindler, Stephen R., Hoeijmakers, Jan H. J., van der Horst, Gijsbertus T. J., Garinis, George A.
Publicado 2008

Metformin improves healthspan and lifespan in mice

por Martin-Montalvo, Alejandro, Mercken, Evi M., Mitchell, Sarah J., Palacios, Hector H., Mote, Patricia L., Scheibye-Knudsen, Morten, Gomes, Ana P., Ward, Theresa M., Minor, Robin K., Blouin, Marie-José, Schwab, Matthias, Pollak, Michael, Zhang, Yongqing, Yu, Yinbing, Becker, Kevin G., Bohr, Vilhelm A., Ingram, Donald K., Sinclair, David A., Wolf, Norman S., Spindler, Stephen R., Bernier, Michel, de Cabo, Rafael
Publicado 2013

Interventions to Slow Aging in Humans: Are We Ready?

por Longo, Valter D, Antebi, Adam, Bartke, Andrzej, Barzilai, Nir, Brown-Borg, Holly M, Caruso, Calogero, Curiel, Tyler J, de Cabo, Rafael, Franceschi, Claudio, Gems, David, Ingram, Donald K, Johnson, Thomas E, Kennedy, Brian K, Kenyon, Cynthia, Klein, Samuel, Kopchick, John J, Lepperdinger, Guenter, Madeo, Frank, Mirisola, Mario G, Mitchell, James R, Passarino, Giuseppe, Rudolph, Karl L, Sedivy, John M, Shadel, Gerald S, Sinclair, David A, Spindler, Stephen R, Suh, Yousin, Vijg, Jan, Vinciguerra, Manlio, Fontana, Luigi
Publicado 2015