MiR-182 promotes cancer invasion by linking RET oncogene activated NF-κB to loss of the HES1/Notch1 regulatory circuit

por Spitschak, Alf, Meier, Claudia, Kowtharapu, Bhavani, Engelmann, David, Pützer, Brigitte M.
Publicado 2017

Drug Repurposing at the Interface of Melanoma Immunotherapy and Autoimmune Disease

por Spitschak, Alf, Gupta, Shailendra, Singh, Krishna P., Logotheti, Stella, Pützer, Brigitte M.
Publicado 2022

Mechanisms of Functional Pleiotropy of p73 in Cancer and Beyond

por Logotheti, Stella, Richter, Christin, Murr, Nico, Spitschak, Alf, Marquardt, Stephan, Pützer, Brigitte M.
Publicado 2021

Epigenetic factor EPC1 is a master regulator of DNA damage response by interacting with E2F1 to silence death and activate metastasis-related gene signatures

por Wang, Yajie, Alla, Vijay, Goody, Deborah, Gupta, Shailendra K., Spitschak, Alf, Wolkenhauer, Olaf, Pützer, Brigitte M., Engelmann, David
Publicado 2016

MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance

por Lai, Xin, Gupta, Shailendra K, Schmitz, Ulf, Marquardt, Stephan, Knoll, Susanne, Spitschak, Alf, Wolkenhauer, Olaf, Pützer, Brigitte M, Vera, Julio
Publicado 2018

Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness

por Richter, Christin, Marquardt, Stephan, Li, Fanghua, Spitschak, Alf, Murr, Nico, Edelhäuser, Berdien A. H., Iliakis, George, Pützer, Brigitte M., Logotheti, Stella
Publicado 2019

Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures

por Khan, Faiz M., Marquardt, Stephan, Gupta, Shailendra K., Knoll, Susanne, Schmitz, Ulf, Spitschak, Alf, Engelmann, David, Vera, Julio, Wolkenhauer, Olaf, Pützer, Brigitte M.
Publicado 2017

Novel integrated workflow allows production and in-depth quality assessment of multifactorial reprogrammed skeletal muscle cells from human stem cells

por Faustino, Dinis, Brinkmeier, Heinrich, Logotheti, Stella, Jonitz-Heincke, Anika, Yilmaz, Hande, Takan, Isil, Peters, Kirsten, Bader, Rainer, Lang, Hermann, Pavlopoulou, Athanasia, Pützer, Brigitte M., Spitschak, Alf
Publicado 2022

LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1

por Logotheti, Stella, Marquardt, Stephan, Gupta, Shailendra K., Richter, Christin, Edelhäuser, Berdien A.H., Engelmann, David, Brenmoehl, Julia, Söhnchen, Christoph, Murr, Nico, Alpers, Michael, Singh, Krishna P., Wolkenhauer, Olaf, Heckl, Dirk, Spitschak, Alf, Pützer, Brigitte M.
Publicado 2020

Drug Repositioning Inferred from E2F1-Coregulator Interactions Studies for the Prevention and Treatment of Metastatic Cancers

por Goody, Deborah, Gupta, Shailendra K., Engelmann, David, Spitschak, Alf, Marquardt, Stephan, Mikkat, Stefan, Meier, Claudia, Hauser, Charlotte, Gundlach, Jan-Paul, Egberts, Jan-Hendrik, Martin, Hubert, Schumacher, Toni, Trauzold, Anna, Wolkenhauer, Olaf, Logotheti, Stella, Pützer, Brigitte M.
Publicado 2019