Conjugation of Natural Triterpenic Acids with Delocalized Lipophilic Cations: Selective Targeting Cancer Cell Mitochondria

por Spivak, Anna Yu., Nedopekina, Darya A., Gubaidullin, Rinat R., Dubinin, Mikhail V., Belosludtsev, Konstantin N.
Publicado 2021

Synthesis and Evaluation of Anticancer Activities of Novel C-28 Guanidine-Functionalized Triterpene Acid Derivatives

por Spivak, Anna, Khalitova, Rezeda, Nedopekina, Darya, Dzhemileva, Lilya, Yunusbaeva, Milyausha, Odinokov, Victor, D’yakonov, Vladimir, Dzhemilev, Usein
Publicado 2018

Effect of F16-Betulin Conjugate on Mitochondrial Membranes and Its Role in Cell Death Initiation

por Dubinin, Mikhail V., Semenova, Alena A., Nedopekina, Darya A., Davletshin, Eldar V., Spivak, Anna Yu., Belosludtsev, Konstantin N.
Publicado 2021

Mitochondria-targeted betulinic and ursolic acid derivatives: synthesis and anticancer activity

por Nedopekina, Darya A., Gubaidullin, Rinat R., Odinokov, Victor N., Maximchik, Polina V., Zhivotovsky, Boris, Bel'skii, Yuriy P., Khazanov, Veniamin A., Manuylova, Arina V., Gogvadze, Vladimir, Spivak, Anna Yu.
Publicado 2017

Conjugation of Triterpenic Acids of Ursane and Oleanane Types with Mitochondria-Targeting Cation F16 Synergistically Enhanced Their Cytotoxicity against Tumor Cells

por Dubinin, Mikhail V., Nedopekina, Darya A., Ilzorkina, Anna I., Semenova, Alena A., Sharapov, Vyacheslav A., Davletshin, Eldar V., Mikina, Natalia V., Belsky, Yuri P., Spivak, Anna Yu., Akatov, Vladimir S., Belosludtseva, Natalia V., Liu, Jiankang, Belosludtsev, Konstantin N.
Publicado 2023

Comparative Study of Cytotoxic and Membranotropic Properties of Betulinic Acid-F16 Conjugate on Breast Adenocarcinoma Cells (MCF-7) and Primary Human Fibroblasts

por Belosludtsev, Konstantin N., Ilzorkina, Anna I., Belosludtseva, Natalia V., Sharapov, Vyacheslav A., Penkov, Nikita V., Serov, Dmitriy A., Karagyaur, Maxim N., Nedopekina, Darya A., Davletshin, Eldar V., Solovieva, Marina E., Spivak, Anna Yu, Kuzmina, Ulyana Sh., Vakhitova, Yulia V., Akatov, Vladimir S., Dubinin, Mikhail V.
Publicado 2022