Image-based crystal detection: a machine-learning approach

por Liu, Roy, Freund, Yoav, Spraggon, Glen
Publicado 2008

Crystal Structure of a Two-Subunit TrkA Octameric Gating Ring Assembly

por Deller, Marc C., Johnson, Hope A., Miller, Mitchell D., Spraggon, Glen, Elsliger, Marc-André, Wilson, Ian A., Lesley, Scott A.
Publicado 2015

The first crystal structure of cyclic GMP-dependent protein kinase Iβ dimerization/docking domain reveals molecular details of isoform-specific anchoring

por Casteel, Darren E, Smith-Nguyen, Eric V, Sankaran, Banumathi, Spraggon, Glen, Hampton, Eric N, Pilz, Renate B, Taylor, Susan S, Kim, Choel
Publicado 2009

Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody

por Maritan, Martina, Veggi, Daniele, Cozzi, Roberta, Dello Iacono, Lucia, Bartolini, Erika, Lo Surdo, Paola, Maruggi, Giulietta, Spraggon, Glen, Bottomley, Matthew J., Malito, Enrico
Publicado 2018

Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus pneumoniae Pilus

por Spraggon, Glen, Koesema, Eric, Scarselli, Maria, Malito, Enrico, Biagini, Massimiliano, Norais, Nathalie, Emolo, Carla, Barocchi, Michèle Anne, Giusti, Fabiola, Hilleringmann, Markus, Rappuoli, Rino, Lesley, Scott, Covacci, Antonello, Masignani, Vega, Ferlenghi, Ilaria
Publicado 2010

FdeC, a Novel Broadly Conserved Escherichia coli Adhesin Eliciting Protection against Urinary Tract Infections

por Nesta, Barbara, Spraggon, Glen, Alteri, Christopher, Gomes Moriel, Danilo, Rosini, Roberto, Veggi, Daniele, Smith, Sara, Bertoldi, Isabella, Pastorello, Ilaria, Ferlenghi, Ilaria, Fontana, Maria Rita, Frankel, Gad, Mobley, Harry L. T., Rappuoli, Rino, Pizza, Mariagrazia, Serino, Laura, Soriani, Marco
Publicado 2012

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

por Cellitti, Susan E., Shaffer, Jennifer, Jones, David H., Mukherjee, Tathagata, Gurumurthy, Meera, Bursulaya, Badry, Boshoff, Helena I., Choi, Inhee, Nayyar, Amit, Lee, Yong Sok, Cherian, Joseph, Niyomrattanakit, Pornwaratt, Dick, Thomas, Manjunatha, Ujjini H., Barry, Clifton E., Spraggon, Glen, Geierstanger, Bernhard H.
Publicado 2012

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

por Cellitti, Susan E., Shaffer, Jennifer, Jones, David H., Mukherjee, Tathagata, Gurumurthy, Meera, Bursulaya, Badry, Boshoff, Helena I., Choi, Inhee, Nayyar, Amit, Lee, Yong Sok, Cherian, Joseph, Niyomrattanakit, Pornwaratt, Dick, Thomas, Manjunatha, Ujjini H., Barry, Clifton E., Spraggon, Glen, Geierstanger, Bernhard H.
Publicado 2013

Discovery of small molecules that target a tertiary-structured RNA

por Menichelli, Elena, Lam, Bianca J., Wang, Yu, Wang, Vivian S., Shaffer, Jennifer, Tjhung, Katrina F., Bursulaya, Badry, Nguyen, Truc Ngoc, Vo, Todd, Alper, Phillip B, McAllister, Christopher S, Jones, David H., Spraggon, Glen, Michellys, Pierre-Yves, Joslin, John, Joyce, Gerald F., Rogers, Jeff
Publicado 2022

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

por Khare, Shilpi, Nagle, Advait S., Biggart, Agnes, Lai, Yin H., Liang, Fang, Davis, Lauren C., Barnes, S. Whitney, Mathison, Casey J. N., Myburgh, Elmarie, Gao, Mu-Yun, Gillespie, J. Robert, Liu, Xianzhong, Tan, Jocelyn L., Stinson, Monique, Rivera, Ianne C., Ballard, Jaime, Yeh, Vince, Groessl, Todd, Federe, Glenn, Koh, Hazel X. Y., Venable, John D., Bursulaya, Badry, Shapiro, Michael, Mishra, Pranab K., Spraggon, Glen, Brock, Ansgar, Mottram, Jeremy C., Buckner, Frederick S., Rao, Srinivasa P. S., Wen, Ben G., Walker, John R., Tuntland, Tove, Molteni, Valentina, Glynne, Richard J., Supek, Frantisek
Publicado 2016

Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases

por Nagle, Advait, Biggart, Agnes, Be, Celine, Srinivas, Honnappa, Hein, Andreas, Caridha, Diana, Sciotti, Richard J., Pybus, Brandon, Kreishman-Deitrick, Mara, Bursulaya, Badry, Lai, Yin H., Gao, Mu-Yun, Liang, Fang, Mathison, Casey J. N., Liu, Xiaodong, Yeh, Vince, Smith, Jeffrey, Lerario, Isabelle, Xie, Yongping, Chianelli, Donatella, Gibney, Michael, Berman, Ashley, Chen, Yen-Liang, Jiricek, Jan, Davis, Lauren C., Liu, Xianzhong, Ballard, Jaime, Khare, Shilpi, Eggimann, Fabian Kurt, Luneau, Alexandre, Groessl, Todd, Shapiro, Michael, Richmond, Wendy, Johnson, Kevin, Rudewicz, Patrick J., Rao, Srinivasa P. S., Thompson, Christopher, Tuntland, Tove, Spraggon, Glen, Glynne, Richard J., Supek, Frantisek, Wiesmann, Christian, Molteni, Valentina
Publicado 2020