New therapeutic approaches for Krabbe disease: The potential of pharmacological chaperones

por Spratley, Samantha J., Deane, Janet E.
Publicado 2016

A Tetrameric Assembly of Saposin A: Increasing Structural Diversity in Lipid Transfer Proteins

por Shamin, Maria, Spratley, Samantha J., Graham  , Stephen C., Deane , Janet E.
Publicado 2021

Protein Kinase D Isoforms Differentially Modulate Cofilin-Driven Directed Cell Migration

por Döppler, Heike, Bastea, Ligia I., Borges, Sahra, Spratley, Samantha J., Pearce, Sarah E., Storz, Peter
Publicado 2014

Molecular Mechanisms of Disease Pathogenesis Differ in Krabbe Disease Variants

por Spratley, Samantha J., Hill, Chris H., Viuff, Agnete H., Edgar, James R., Skjødt, Karsten, Deane, Janet E.
Publicado 2016

The mechanism of glycosphingolipid degradation revealed by a GALC-SapA complex structure

por Hill, Chris H., Cook, Georgia M., Spratley, Samantha J., Fawke, Stuart, Graham, Stephen C., Deane, Janet E.
Publicado 2018

Azasugar inhibitors as pharmacological chaperones for Krabbe disease

por Hill, Chris H., Viuff, Agnete H., Spratley, Samantha J., Salamone, Stéphane, Christensen, Stig H., Read, Randy J., Moriarty, Nigel W., Jensen, Henrik H., Deane, Janet E.
Publicado 2015

A simeprevir-inducible molecular switch for the control of cell and gene therapies

por Chin, Stacey E., Schindler, Christina, Vinall, Lisa, Dodd, Roger B., Bamber, Lisa, Legg, Sandrine, Sigurdardottir, Anna, Rees, D. Gareth, Malcolm, Tim I. M., Spratley, Samantha J., Granéli, Cecilia, Sumner, Jonathan, Tigue, Natalie J.
Publicado 2023