Common framework mutations impact antibody interfacial dynamics and flexibility

por Rhodes, Emily R., Faris, Jonathan G., Petersen, Brian M., Sprenger, Kayla G.
Publicado 2023

Moving the needle: Employing deep reinforcement learning to push the boundaries of coarse-grained vaccine models

por Faris, Jonathan G., Orbidan, Daniel, Wells, Charles, Petersen, Brenden K., Sprenger, Kayla G.
Publicado 2022

Multiscale affinity maturation simulations to elicit broadly neutralizing antibodies against HIV

por Conti, Simone, Ovchinnikov, Victor, Faris, Jonathan G., Chakraborty, Arup K., Karplus, Martin, Sprenger, Kayla G.
Publicado 2022

Using Synthetic ApoC-II Peptides and nAngptl4 Fragments to Measure Lipoprotein Lipase Activity in Radiometric and Fluorescent Assays

por Oldham, Dean, Wang, Hong, Mullen, Juliet, Lietzke, Emma, Sprenger, Kayla, Reigan, Philip, Eckel, Robert H., Bruce, Kimberley D.
Publicado 2022

Regulatory Approved Monoclonal Antibodies Contain Framework Mutations Predicted From Human Antibody Repertoires

por Petersen, Brian M., Ulmer, Sophia A., Rhodes, Emily R., Gutierrez-Gonzalez, Matias F., Dekosky, Brandon J., Sprenger, Kayla G., Whitehead, Timothy A.
Publicado 2021

One-shot identification of SARS-CoV-2 S RBD escape mutants using yeast screening

por Urdaniz, Irene Francino, Steiner, Paul J., Kirby, Monica B., Zhao, Fangzhu, Haas, Cyrus M., Barman, Shawn, Rhodes, Emily R., Peng, Linghang, Sprenger, Kayla G., Jardine, Joseph G., Whitehead, Timothy A.
Publicado 2021

One-shot identification of SARS-CoV-2 S RBD escape mutants using yeast screening

por Francino-Urdaniz, Irene M., Steiner, Paul J., Kirby, Monica B., Zhao, Fangzhu, Haas, Cyrus M., Barman, Shawn, Rhodes, Emily R., Leonard, Alison C., Peng, Linghang, Sprenger, Kayla G., Jardine, Joseph G., Whitehead, Timothy A.
Publicado 2021

Roadmap on biology in time varying environments

por Murugan, Arvind, Husain, Kabir, Rust, Michael J, Hepler, Chelsea, Bass, Joseph, Pietsch, Julian M J, Swain, Peter S, Jena, Siddhartha G, Toettcher, Jared E, Chakraborty, Arup K, Sprenger, Kayla G, Mora, T, Walczak, A M, Rivoire, O, Wang, Shenshen, Wood, Kevin B, Skanata, Antun, Kussell, Edo, Ranganathan, Rama, Shih, Hong-Yan, Goldenfeld, Nigel
Publicado 2021