Using Peptidomimetics and Constrained Peptides as Valuable Tools for Inhibiting Protein–Protein Interactions

por Robertson, Naomi S., Spring, David R.
Publicado 2018

Divergent Synthesis of Quinolone Natural Products from Pseudonocardia sp. CL38489

por Geddis, Stephen M., Carro, Laura, Hodgkinson, James T., Spring, David R.
Publicado 2016

Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics

por Charoenpattarapreeda, Jiraborrirak, Walsh, Stephen J., Carroll, Jason S., Spring, David R.
Publicado 2020

A new Pseudomonas quinolone signal (PQS) binding partner: MexG

por Hodgkinson, James T., Gross, Jeremy, Baker, Ysobel R., Spring, David R., Welch, M.
Publicado 2016

Synthesis and Reactivity of a Bis-Strained Alkyne Derived from 1,1′-Biphenyl-2,2′,6,6′-tetrol

por Knighton, Richard C., Sharma, Krishna, Robertson, Naomi S., Spring, David R., Wills, Martin
Publicado 2019

Quantitatively Mapping Cellular Viscosity with Detailed Organelle Information via a Designed PET Fluorescent Probe

por Liu, Tianyu, Liu, Xiaogang, Spring, David R., Qian, Xuhong, Cui, Jingnan, Xu, Zhaochao
Publicado 2014

Structural and calorimetric studies demonstrate that the hepatocyte nuclear factor 1β (HNF1β) transcription factor is imported into the nucleus via a monopartite NLS sequence

por Wiedmann, Mareike M., Aibara, Shintaro, Spring, David R., Stewart, Murray, Brenton, James D.
Publicado 2016

Design and Synthesis of a Biotinylated Chemical Probe for Detecting the Molecular Targets of an Inhibitor of the Production of the Pseudomonas aeruginosa Virulence Factor Pyocyanin

por Baker, Ysobel R., Galloway, Warren R. J. D., Hodgkinson, James T., Spring, David R.
Publicado 2013

The multifaceted nature of antimicrobial peptides: current synthetic chemistry approaches and future directions

por Gan, Bee Ha, Gaynord, Josephine, Rowe, Sam M., Deingruber, Tomas, Spring, David R.
Publicado 2021

Correction: The multifaceted nature of antimicrobial peptides: current synthetic chemistry approaches and future directions

por Gan, Bee Ha, Gaynord, Josephine, Rowe, Sam M., Deingruber, Tomas, Spring, David R.
Publicado 2021

Synthesis of sp(3)-rich heterocyclic frameworks by a divergent synthesis strategy

por Mortensen, Kim T., Wong, Denedy S. Y., King, Thomas A., Sore, Hannah F., Spring, David R.
Publicado 2023

Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions

por Laraia, Luca, McKenzie, Grahame, Spring, David R., Venkitaraman, Ashok R., Huggins, David J.
Publicado 2015

Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections

por Kidd, Sarah L., Osberger, Thomas J., Mateu, Natalia, Sore, Hannah F., Spring, David R.
Publicado 2018

Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products

por Geddis, Stephen M, Coroama, Teodora, Forrest, Suzanne, Hodgkinson, James T, Welch, Martin, Spring, David R
Publicado 2018

Stereocontrolled semi-syntheses of deguelin and tephrosin

por Russell, David A., Freudenreich, Julien J., Ciardiello, Joe J., Sore, Hannah F., Spring, David R.
Publicado 2017

Diversity-oriented synthesis of heterocycles and macrocycles by controlled reactions of oxetanes with α-iminocarbenes

por Guarnieri-Ibáñez, Alejandro, Medina, Florian, Besnard, Céline, Kidd, Sarah L., Spring, David R., Lacour, Jérôme
Publicado 2017

Rapid and robust cysteine bioconjugation with vinylheteroarenes

por Seki, Hikaru, Walsh, Stephen J., Bargh, Jonathan D., Parker, Jeremy S., Carroll, Jason, Spring, David R.
Publicado 2021

Identification of macrocyclic peptides which activate bacterial cylindrical proteases

por Walther, Raoul, Westermann, Linda M., Carmali, Sheiliza, Jackson, Sophie E., Brötz-Oesterhelt, Heike, Spring, David R.
Publicado 2023

Two-directional synthesis as a tool for diversity-oriented synthesis: Synthesis of alkaloid scaffolds

por O’Connell, Kieron M G, Díaz-Gavilán, Monica, Galloway, Warren R J D, Spring, David R
Publicado 2012

Downfalls of Chemical Probes Acting at the Kinase ATP-Site: CK2 as a Case Study

por Atkinson, Eleanor L., Iegre, Jessica, Brear, Paul D., Zhabina, Elizabeth A., Hyvönen, Marko, Spring, David R.
Publicado 2021