Cbl Negatively Regulates JNK Activation and Cell Death

por Sproul, Andrew A., Xu, Zhiheng, Wilhelm, Michael, Gire, Stephen, Greene, Lloyd A.
Publicado 2009

A Time Course Analysis of the Electrophysiological Properties of Neurons Differentiated from Human Induced Pluripotent Stem Cells (iPSCs)

por Prè, Deborah, Nestor, Michael W., Sproul, Andrew A., Jacob, Samson, Koppensteiner, Peter, Chinchalongporn, Vorapin, Zimmer, Matthew, Yamamoto, Ai, Noggle, Scott A., Arancio, Ottavio
Publicado 2014

Generation of iPSC lines from archived non-cryoprotected biobanked dura mater

por Sproul, Andrew A, Vensand, Lauren B, Dusenberry, Carmen R, Jacob, Samson, Vonsattel, Jean Paul G, Paull, Daniel J, Shelanski, Michael L, Crary, John F, Noggle, Scott A
Publicado 2014

Improved Methods for Reprogramming Human Dermal Fibroblasts Using Fluorescence Activated Cell Sorting

por Kahler, David J., Ahmad, Faizzan S., Ritz, Anita, Hua, Haiqing, Moroziewicz, Dorota N., Sproul, Andrew A., Dusenberry, Carmen R., Shang, Linshan, Paull, Daniel, Zimmer, Matthew, Weiss, Keren A., Egli, Dieter, Noggle, Scott A.
Publicado 2013

RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation

por Kim, Yoon A., Siddiqui, Tohid, Blaze, Jennifer, Cosacak, Mehmet Ilyas, Winters, Tristan, Kumar, Atul, Tein, Ellen, Sproul, Andrew A., Teich, Andrew F., Bartolini, Francesca, Akbarian, Schahram, Kizil, Caghan, Hargus, Gunnar, Santa-Maria, Ismael
Publicado 2022

The Alzheimer's disease‐associated C99 fragment of APP regulates cellular cholesterol trafficking

por Montesinos, Jorge, Pera, Marta, Larrea, Delfina, Guardia‐Laguarta, Cristina, Agrawal, Rishi R, Velasco, Kevin R, Yun, Taekyung D, Stavrovskaya, Irina G, Xu, Yimeng, Koo, So Yeon, Snead, Amanda M, Sproul, Andrew A, Area‐Gomez, Estela
Publicado 2020

Characterization and Molecular Profiling of PSEN1 Familial Alzheimer's Disease iPSC-Derived Neural Progenitors

por Sproul, Andrew A., Jacob, Samson, Pre, Deborah, Kim, Soong Ho, Nestor, Michael W., Navarro-Sobrino, Miriam, Santa-Maria, Ismael, Zimmer, Matthew, Aubry, Soline, Steele, John W., Kahler, David J., Dranovsky, Alex, Arancio, Ottavio, Crary, John F., Gandy, Sam, Noggle, Scott A.
Publicado 2014

CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage

por Sun, Jichao, Carlson-Stevermer, Jared, Das, Utpal, Shen, Minjie, Delenclos, Marion, Snead, Amanda M., Koo, So Yeon, Wang, Lina, Qiao, Dianhua, Loi, Jonathan, Petersen, Andrew J., Stockton, Michael, Bhattacharyya, Anita, Jones, Mathew V., Zhao, Xinyu, McLean, Pamela J., Sproul, Andrew A., Saha, Krishanu, Roy, Subhojit
Publicado 2019

Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics

por Bosc, Elodie, Anastasie, Julie, Soualmia, Feryel, Coric, Pascale, Kim, Ju Youn, Wang, Lily Q., Lacin, Gullen, Zhao, Kaitao, Patel, Ronak, Duplus, Eric, Tixador, Philippe, Sproul, Andrew A., Brugg, Bernard, Reboud-Ravaux, Michelle, Troy, Carol M., Shelanski, Michael L., Bouaziz, Serge, Karin, Michael, El Amri, Chahrazade, Jacotot, Etienne D.
Publicado 2022

ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer’s disease

por Bartosch, Anne Marie W., Youth, Elliot H. H., Hansen, Shania, Kaufman, Maria E., Xiao, Harrison, Koo, So Yeon, Ashok, Archana, Sivakumar, Sharanya, Soni, Rajesh K., Dumitrescu, Logan C., Lam, Tiffany G., Ropri, Ali S., Lee, Annie J., Klein, Hans-Ulrich, Vardarajan, Badri N., Bennett, David A., Young-Pearse, Tracy L., De Jager, Philip L., Hohman, Timothy J., Sproul, Andrew A., Teich, Andrew F.
Publicado 2023