Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates

por Langer, Henning Tim, Afzal, Shoaib, Kempa, Stefan, Spuler, Simone
Publicado 2020

Delay in diagnosis of muscle disorders depends on the subspecialty of the initially consulted physician

por Spuler, Simone, Stroux, Andrea, Kuschel, Franziska, Kuhlmey, Adelheid, Kendel, Friederike
Publicado 2011

Full-length Dysferlin Transfer by the Hyperactive Sleeping Beauty Transposase Restores Dysferlin-deficient Muscle

por Escobar, Helena, Schöwel, Verena, Spuler, Simone, Marg, Andreas, Izsvák, Zsuzsanna
Publicado 2016

Ahnak1 abnormally localizes in muscular dystrophies and contributes to muscle vesicle release

por Zacharias, Ute, Purfürst, Bettina, Schöwel, Verena, Morano, Ingo, Spuler, Simone, Haase, Hannelore
Publicado 2011

Dysferlin-deficient immortalized human myoblasts and myotubes as a useful tool to study dysferlinopathy

por Philippi, Susanne, Bigot, Anne, Marg, Andreas, Mouly, Vincent, Spuler, Simone, Zacharias, Ute
Publicado 2012

LMNA Co-Regulated Gene Expression as a Suitable Readout after Precise Gene Correction

por Wang, Haicui, Krause, Anne, Escobar, Helena, Müthel, Stefanie, Metzler, Eric, Spuler, Simone
Publicado 2022

A Molecular Signature of Myalgia in Myotonic Dystrophy 2

por Moshourab, Rabih, Palada, Vinko, Grunwald, Stefanie, Grieben, Ulrike, Lewin, Gary R., Spuler, Simone
Publicado 2016

mRNA-mediated delivery of gene editing tools to human primary muscle stem cells

por Stadelmann, Christian, Di Francescantonio, Silvia, Marg, Andreas, Müthel, Stefanie, Spuler, Simone, Escobar, Helena
Publicado 2022

Skeletal Muscle 11beta-HSD1 Controls Glucocorticoid-Induced Proteolysis and Expression of E3 Ubiquitin Ligases Atrogin-1 and MuRF-1

por Biedasek, Katrin, Andres, Janin, Mai, Knut, Adams, Stephanie, Spuler, Simone, Fielitz, Jens, Spranger, Joachim
Publicado 2011

MyoMiner: explore gene co-expression in normal and pathological muscle

por Malatras, Apostolos, Michalopoulos, Ioannis, Duguez, Stéphanie, Butler-Browne, Gillian, Spuler, Simone, Duddy, William J.
Publicado 2020

Statins Aggravate the Risk of Insulin Resistance in Human Muscle

por Grunwald, Stefanie A., Haafke, Stefanie, Grieben, Ulrike, Kassner, Ursula, Steinhagen-Thiessen, Elisabeth, Spuler, Simone
Publicado 2022

Generation of hiPSC-Derived Skeletal Muscle Cells: Exploiting the Potential of Skeletal Muscle-Derived hiPSCs

por Metzler, Eric, Escobar, Helena, Sunaga-Franze, Daniele Yumi, Sauer, Sascha, Diecke, Sebastian, Spuler, Simone
Publicado 2022

Cas9-induced single cut enables highly efficient and template-free repair of a muscular dystrophy causing founder mutation

por Müthel, Stefanie, Marg, Andreas, Ignak, Busem, Kieshauer, Janine, Escobar, Helena, Stadelmann, Christian, Spuler, Simone
Publicado 2023

Progressive myocardial injury in myotonic dystrophy type II and facioscapulohumeral muscular dystrophy 1: a cardiovascular magnetic resonance follow-up study

por Blaszczyk, Edyta, Lim, Carolin, Kellman, Peter, Schmacht, Luisa, Gröschel, Jan, Spuler, Simone, Schulz-Menger, Jeanette
Publicado 2021

Myofibrillar protein synthesis rates are increased in chronically exercised skeletal muscle despite decreased anabolic signaling

por Langer, Henning T., West, Daniel, Senden, Joan, Spuler, Simone, van Loon, Luc J. C., Baar, Keith
Publicado 2022

Loss of Ptpn11 (Shp2) drives satellite cells into quiescence

por Griger, Joscha, Schneider, Robin, Lahmann, Ines, Schöwel, Verena, Keller, Charles, Spuler, Simone, Nazare, Marc, Birchmeier, Carmen
Publicado 2017

Dysferlin-Peptides Reallocate Mutated Dysferlin Thereby Restoring Function

por Schoewel, Verena, Marg, Andreas, Kunz, Severine, Overkamp, Tim, Siegert Carrazedo, Romy, Zacharias, Ute, Daniel, Peter T., Spuler, Simone
Publicado 2012

Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells

por Kim, Minchul, Franke, Vedran, Brandt, Bettina, Lowenstein, Elijah D., Schöwel, Verena, Spuler, Simone, Akalin, Altuna, Birchmeier, Carmen
Publicado 2020

Muscle Atrophy Due to Nerve Damage Is Accompanied by Elevated Myofibrillar Protein Synthesis Rates

por Langer, Henning T., Senden, Joan M. G., Gijsen, Annemie P., Kempa, Stefan, van Loon, Luc J. C., Spuler, Simone
Publicado 2018

4-Phenylbutyrate restores localization and membrane repair to human dysferlin mutations

por Tominaga, Kana, Tominaga, Naoomi, Williams, Eric O., Rufibach, Laura, Schöwel, Verena, Spuler, Simone, Viswanathan, Mohan, Guarente, Leonard P.
Publicado 2021