Active site polymerase inhibitor nucleotides (ASPINs): Potential agents for chronic HBV cure regimens

por Gish, Robert G, Asselah, Tarik, Squires, Katherine, Mayers, Douglas
Publicado 2022

A randomized phase 1b trial of the active site polymerase inhibitor nucleotide ATI‐2173 in patients with chronic hepatitis B virus infection

por Squires, Katherine E., Ogilvie, Lauren, Jucov, Alina, Anastasiy, Igor, Ghicavii, Nelli, Huguet, Jade, Melara, Rebeca, Constantineau, Martin, De La Rosa, Abel, Mayers, Douglas L.
Publicado 2022

ATI-2173, a Novel Liver-Targeted Non-Chain-Terminating Nucleotide for Hepatitis B Virus Cure Regimens

por Squires, Katherine E., Mayers, Douglas L., Bluemling, Gregory R., Kolykhalov, Alexander A., Guthrie, David B., Reddy, Prabhakar, Mitchell, Debbie G., Saindane, Manohar T., Sticher, Zachary M., Edpuganti, Vindhya, De La Rosa, Abel
Publicado 2020

RGS14 regulates PTH- and FGF23-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein

por Friedman, Peter A., Sneddon, W. Bruce, Mamonova, Tatyana, Montanez-Miranda, Carolina, Ramineni, Suneela, Harbin, Nicholas H., Squires, Katherine E., Gefter, Julia V., Magyar, Clara E., Emlet, David R., Hepler, John R.
Publicado 2022

Human Bacterial Artificial Chromosome (BAC) Transgenesis Fully Rescues Noradrenergic Function in Dopamine β-Hydroxylase Knockout Mice

por Cubells, Joseph F., Schroeder, Jason P., Barrie, Elizabeth S., Manvich, Daniel F., Sadee, Wolfgang, Berg, Tiina, Mercer, Kristina, Stowe, Taylor A., Liles, L. Cameron, Squires, Katherine E., Mezher, Andrew, Curtin, Patrick, Perdomo, Dannie L., Szot, Patricia, Weinshenker, David
Publicado 2016

Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons

por Squires, Katherine E., Gerber, Kyle J., Tillman, Matthew C., Lustberg, Daniel J., Montañez-Miranda, Carolina, Zhao, Meilan, Ramineni, Suneela, Scharer, Christopher D., Saha, Ramendra N., Shu, Feng-Jue, Schroeder, Jason P., Ortlund, Eric A., Weinshenker, David, Dudek, Serena M., Hepler, John R.
Publicado 2020

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets

por Alexander, Stephen P H, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Buneman, O Peter, Cidlowski, John A, Christopoulos, Arthur, Davenport, Anthony P, Fabbro, Doriano, Spedding, Michael, Striessnig, Jörg, Davies, Jamie A, Ahlers‐Dannen, Katelin E., Alqinyah, Mohammed, Arumugam, Thiruma V., Bodle, Christopher, Dagner, Josephine Buo, Chakravarti, Bandana, Choudhuri, Shreoshi P., Druey, Kirk M., Fisher, Rory A., Gerber, Kyle J., Hepler, John R., Hooks, Shelley B., Kantheti, Havish S., Karaj, Behirda, Layeghi‐Ghalehsoukhteh, Somayeh, Lee, Jae‐Kyung, Luo, Zili, Martemyanov, Kirill, Mascarenhas, Luke D., McNabb, Harrison, Montañez‐Miranda, Carolina, Ogujiofor, Osita, Phan, Hoa, Roman, David L., Shaw, Vincent, Sjogren, Benita, Sobey, Christopher, Spicer, Mackenzie M., Squires, Katherine E., Sutton, Laurie, Wendimu, Menbere, Wilkie, Thomas, Xie, Keqiang, Zhang, Qian, Zolghadri, Yalda
Publicado 2021