Physicochemical and biological impact of metal-catalyzed oxidation of IgG1 monoclonal antibodies and antibody-drug conjugates via reactive oxygen species

por Glover, Zephania Kwong, Wecksler, Aaron, Aryal, Baikuntha, Mehta, Shrenik, Pegues, Melissa, Chan, Wayman, Lehtimaki, Mari, Luo, Allen, Sreedhara, Alavattam, Rao, V. Ashutosh
Publicado 2022

Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanisms

por Hecht, Elizabeth Sara, Mehta, Shrenik, Wecksler, Aaron T., Aguilar, Ben, Swanson, Nathaniel, Phung, Wilson, Dubey Kelsoe, Ananya, Benner, W. Henry, Tesar, Devin, Kelley, Robert F., Sandoval, Wendy, Sreedhara, Alavattam
Publicado 2022

Translational Approaches for Brain Delivery of Biologics via Cerebrospinal Fluid

por Sadekar, Shraddha S., Bowen, Mayumi, Cai, Hao, Jamalian, Samira, Rafidi, Hanine, Shatz‐Binder, Whitney, Lafrance‐Vanasse, Julien, Chan, Pamela, Meilandt, William J., Oldendorp, Amy, Sreedhara, Alavattam, Daugherty, Ann, Crowell, Susan, Wildsmith, Kristin R., Atwal, Jasvinder, Fuji, Reina N., Horvath, Joshua
Publicado 2022