Mechanisms of protection of retinal pigment epithelial cells from oxidant injury by humanin and other mitochondrial-derived peptides: Implications for age-related macular degenerat...

por Sreekumar, Parameswaran G., Kannan, Ram
Publicado 2020

Endoplasmic reticulum-mitochondrial crosstalk: a novel role for the mitochondrial peptide humanin

por Sreekumar, Parameswaran G., Hinton, David R., Kannan, Ram
Publicado 2017

The Emerging Role of Senescence in Ocular Disease

por Sreekumar, Parameswaran G., Hinton, David R., Kannan, Ram
Publicado 2020

Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration

por Sreekumar, Parameswaran G., Ferrington, Deborah A., Kannan, Ram
Publicado 2021

Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells

por Minasyan, Leonid, Sreekumar, Parameswaran G., Hinton, David R., Kannan, Ram
Publicado 2017

Transporter-Mediated Mitochondrial GSH Depletion Leading to Mitochondrial Dysfunction and Rescue with αB Crystallin Peptide in RPE Cells

por Sreekumar, Parameswaran G, Wang, Mo, Spee, Christine, Sadda, Srinivas R., Kannan, Ram
Publicado 2020

Protection of Retina by αB Crystallin in Sodium Iodate Induced Retinal Degeneration

por Zhou, Peng, Kannan, Ram, Spee, Christine, Sreekumar, Parameswaran G., Dou, Guorui, Hinton, David R.
Publicado 2014

Mechanisms of Epithelial-Mesenchymal Transition and Prevention of Dispase-Induced PVR by Delivery of an Antioxidant αB Crystallin Peptide †

por Wada, Iori, Sreekumar, Parameswaran G, Spee, Christine, MacKay, Andrew J, Ip, Michael, Kannan, Ram
Publicado 2022

Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration

por Sonoda, Shozo, Sreekumar, Parameswaran G., Kase, Satoru, Spee, Christine, Ryan, Stephen J, Kannan, Ram, Hinton, David R
Publicado 2009

αB Crystallin Is Apically Secreted within Exosomes by Polarized Human Retinal Pigment Epithelium and Provides Neuroprotection to Adjacent Cells

por Sreekumar, Parameswaran G., Kannan, Ram, Kitamura, Mizuki, Spee, Christine, Barron, Ernesto, Ryan, Stephen J., Hinton, David R.
Publicado 2010

Mechanism of RPE Cell Death in α-Crystallin Deficient Mice: A Novel and Critical Role for MRP1-Mediated GSH Efflux

por Sreekumar, Parameswaran G., Spee, Christine, Ryan, Stephen J., Cole, Susan P. C., Kannan, Ram, Hinton, David R.
Publicado 2012

Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione

por Matsunaga, Douglas, Sreekumar, Parameswaran G., Ishikawa, Keijiro, Terasaki, Hiroto, Barron, Ernesto, Cohen, Pinchas, Kannan, Ram, Hinton, David R.
Publicado 2016

Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells

por Wang, Mo, Lau, Lin-Ing, Sreekumar, Parameswaran G., Spee, Christine, Hinton, David R., Sadda, Srinivas R., Kannan, Ram
Publicado 2019

The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction

por Sreekumar, Parameswaran G., Ishikawa, Keijiro, Spee, Chris, Mehta, Hemal H., Wan, Junxiang, Yen, Kelvin, Cohen, Pinchas, Kannan, Ram, Hinton, David R.
Publicado 2016

αB-Crystallin Peptide Fused with Elastin-like Polypeptide: Intracellular Activity in Retinal Pigment Epithelial Cells Challenged with Oxidative Stress †

por Attia, Sara Aly, Truong, Anh Tan, Phan, Alvin, Lee, Shin-Jae, Abanmai, Manal, Markanovic, Marinella, Avila, Hugo, Luo, Haozhong, Ali, Atham, Sreekumar, Parameswaran G., Kannan, Ram, MacKay, J. Andrew
Publicado 2023