Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis

por Størling, Joachim, Pociot, Flemming
Publicado 2017

Cathepsin C Regulates Cytokine-Induced Apoptosis in β-Cell Model Systems

por Fløyel, Tina, Frørup, Caroline, Størling, Joachim, Pociot, Flemming
Publicado 2021

A Dual Systems Genetics Approach Identifies Common Genes, Networks, and Pathways for Type 1 and 2 Diabetes in Human Islets

por Kaur, Simranjeet, Mirza, Aashiq H., Overgaard, Anne J., Pociot, Flemming, Størling, Joachim
Publicado 2021

Systemic TNFα correlates with residual β-cell function in children and adolescents newly diagnosed with type 1 diabetes

por Overgaard, Anne Julie, Madsen, Jens Otto Broby, Pociot, Flemming, Johannesen, Jesper, Størling, Joachim
Publicado 2020

Low-grade inflammation in type 2 diabetes: a cross-sectional study from a Danish diabetes outpatient clinic

por Okdahl, Tina, Wegeberg, Anne-Marie, Pociot, Flemming, Brock, Birgitte, Størling, Joachim, Brock, Christina
Publicado 2022

Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice

por Pedersen, Signe Schultz, Prause, Michala, Sørensen, Christina, Størling, Joachim, Moritz, Thomas, Mariño, Eliana, Billestrup, Nils
Publicado 2023

Cross-sectional study investigating the association between inflammatory biomarkers and neuropathy in adolescents with type 1 diabetes

por Rasmussen, Vinni Faber, Hirschberg Jensen, Verena, Thrysøe, Mathilde, Vestergaard, Esben Thyssen, Størling, Joachim, Kristensen, Kurt
Publicado 2023

JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression

por Prause, Michala, Mayer, Christopher Michael, Brorsson, Caroline, Frederiksen, Klaus Stensgaard, Billestrup, Nils, Størling, Joachim, Mandrup-Poulsen, Thomas
Publicado 2016

Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes

por Wegeberg, Anne-Marie L., Okdahl, Tina, Fløyel, Tina, Brock, Christina, Ejskjaer, Niels, Riahi, Sam, Pociot, Flemming, Størling, Joachim, Brock, Birgitte
Publicado 2020

Effect of liraglutide on expression of inflammatory genes in type 2 diabetes

por Zobel, Emilie H., Ripa, Rasmus S., von Scholten, Bernt J., Rotbain Curovic, Viktor, Kjaer, Andreas, Hansen, Tine W., Rossing, Peter, Størling, Joachim
Publicado 2021

Systemic Cytokine Expression in Diabetes Is Associated with Prolonged Gastrointestinal Transit Times and Cardinal Gastroparesis Symptoms

por Okdahl, Tina, Wegeberg, Anne-Marie, Jensen, Anne Birthe Helweg, Jensen, Sarah Thorius, Andersen, Helene Riis Pontoppidan, Størling, Joachim, Brock, Birgitte, Brock, Christina
Publicado 2023

Associations between Postprandial Gut Hormones and Markers of Bone Remodeling

por Jensen, Nina Wittorff, Clemmensen, Kim Katrine Bjerring, Jensen, Marie Møller, Pedersen, Hanne, Færch, Kristine, Diaz, Lars Jorge, Quist, Jonas Salling, Størling, Joachim
Publicado 2021

Characterization of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cells

por Frørup, Caroline, Gerwig, Rebekka, Svane, Cecilie Amalie Søndergaard, Mendes Lopes de Melo, Joana, Henriksen, Kristine, Fløyel, Tina, Pociot, Flemming, Kaur, Simranjeet, Størling, Joachim
Publicado 2023

Proinflammatory Cytokines Activate the Intrinsic Apoptotic Pathway in β-Cells

por Grunnet, Lars G., Aikin, Reid, Tonnesen, Morten F., Paraskevas, Steven, Blaabjerg, Lykke, Størling, Joachim, Rosenberg, Lawrence, Billestrup, Nils, Maysinger, Dusica, Mandrup-Poulsen, Thomas
Publicado 2009

Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic β Cells

por Kaur, Simranjeet, Frørup, Caroline, Mirza, Aashiq H., Fløyel, Tina, Yarani, Reza, Colli, Maikel L., Johannesen, Jesper, Størling, Joachim, Eizirik, Decio L., Pociot, Flemming
Publicado 2022

SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients

por Fløyel, Tina, Meyerovich, Kira, Prause, Michala C., Kaur, Simranjeet, Frørup, Caroline, Mortensen, Henrik B., Nielsen, Lotte B., Pociot, Flemming, Cardozo, Alessandra K., Størling, Joachim
Publicado 2021

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression

por Bergholdt, Regine, Brorsson, Caroline, Palleja, Albert, Berchtold, Lukas A., Fløyel, Tina, Bang-Berthelsen, Claus Heiner, Frederiksen, Klaus Stensgaard, Jensen, Lars Juhl, Størling, Joachim, Pociot, Flemming
Publicado 2012

CEBPA exerts a specific and biologically important proapoptotic role in pancreatic β cells through its downstream network targets

por Barbagallo, Davide, Condorelli, Angelo Giuseppe, Piro, Salvatore, Parrinello, Nunziatina, Fløyel, Tina, Ragusa, Marco, Rabuazzo, Agata Maria, Størling, Joachim, Purrello, Francesco, Di Pietro, Cinzia, Purrello, Michele
Publicado 2014

Increased mitochondrial proton leak and glycolysis in peripheral blood mononuclear cells in type-1-diabetes

por Lopes de Melo, Joana Mendes, Laursen, Jens Christian, Søndergaard-Heinrich, Niels, Bull Rasmussen, Ida Kirstine, Hansen, Christian Stevns, Frimodt-Møller, Marie, Rossing, Peter, Størling, Joachim
Publicado 2022

No effect of the turmeric root phenol curcumin on prednisolone-induced glucometabolic perturbations in men with overweight or obesity

por Hellmann, Pernille H, Bagger, Jonatan I, Carlander, Katrine R, Hansen, Katrine B, Forman, Julie L, Størling, Joachim, Chabanova, Elizaveta, Holst, Jens, Vilsbøll, Tina, Knop, Filip K
Publicado 2023