Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP

por Cummings, J, Ward, T H, LaCasse, E, Lefebvre, C, St-Jean, M, Durkin, J, Ranson, M, Dive, C
Publicado 2005

Method validation and preliminary qualification of pharmacodynamic biomarkers employed to evaluate the clinical efficacy of an antisense compound (AEG35156) targeted to the X-linke...

por Cummings, J, Ranson, M, LaCasse, E, Ganganagari, J R, St-Jean, M, Jayson, G, Durkin, J, Dive, C
Publicado 2006

SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds

por Cheung, H H, St Jean, M, Beug, S T, Lejmi-Mrad, R, LaCasse, E, Baird, S D, Stojdl, D F, Screaton, R A, Korneluk, R G
Publicado 2011