The Grb2 splice variant, Grb3-3, is a negative regulator of RAS activation

por Seiler, Caroline, Stainthorp, Amy K., Ketchen, Sophie, Jones, Christopher M., Marks, Kate, Quirke, Philip, Ladbury, John E.
Publicado 2022

Targeting the Shc-EGFR interaction with indomethacin inhibits MAP kinase pathway signalling

por Lin, Chi-Chuan, Suen, Kin Man, Stainthorp, Amy, Wieteska, Lukasz, Biggs, George S., Leitão, Andrei, Montanari, Carlos A., Ladbury, John E.
Publicado 2019

Regulation of microRNA expression by the adaptor protein GRB2

por Stainthorp, Amy K., Lin, Chi-Chuan, Wang, Dapeng, Medhi, Ragini, Ahmed, Zamal, Suen, Kin Man, Miska, Eric A., Whitehouse, Adrian, Ladbury, John E.
Publicado 2023

Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state

por Lin, Chi-Chuan, Suen, Kin Man, Jeffrey, Polly-Anne, Wieteska, Lukasz, Lidster, Jessica A., Bao, Peng, Curd, Alistair P., Stainthorp, Amy, Seiler, Caroline, Koss, Hans, Miska, Eric, Ahmed, Zamal, Evans, Stephen D., Molina-París, Carmen, Ladbury, John E.
Publicado 2022

Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins

por Alzahofi, Noura, Welz, Tobias, Robinson, Christopher L., Page, Emma L., Briggs, Deborah A., Stainthorp, Amy K., Reekes, James, Elbe, David A., Straub, Felix, Kallemeijn, Wouter W., Tate, Edward W., Goff, Philip S., Sviderskaya, Elena V., Cantero, Marta, Montoliu, Lluis, Nedelec, Francois, Miles, Amanda K., Bailly, Maryse, Kerkhoff, Eugen, Hume, Alistair N.
Publicado 2020