The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome

por Wlodaver, Alissa M., Staley, Jonathan P.
Publicado 2014

Termination of pre-mRNA splicing requires that the ATPase and RNA unwindase Prp43p acts on the catalytic snRNA U6

por Toroney, Rebecca, Nielsen, Klaus H., Staley, Jonathan P.
Publicado 2019

Synthesis and Incorporation of the Phosphoramidite Derivative of 2′-O-Photocaged 3′-S-Thioguanosine into Oligoribonucleotides: Substrate for Probing the Mechanism of RNA Catalysis...

por Li, Nan-Sheng, Tuttle, Nicole, Staley, Jonathan P., Piccirilli, Joseph A.
Publicado 2014

Sequencing of lariat termini in S. cerevisiae reveals 5′ splice sites, branch points, and novel splicing events

por Qin, Daoming, Huang, Lei, Wlodaver, Alissa, Andrade, Jorge, Staley, Jonathan P.
Publicado 2016

Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA

por He, Yangzi, Staley, Jonathan P., Andersen, Gregers Rom, Nielsen, Klaus H.
Publicado 2017

Evidence for a group II intron-like catalytic triplex in the spliceosome

por Fica, Sebastian M., Mefford, Melissa A., Piccirilli, Joseph A., Staley, Jonathan P.
Publicado 2014

Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish

por Liu, Yuan, Chen, Xue, Qin, Bing, Zhao, Kanxing, Zhao, Qingshun, Staley, Jonathan P., Zhao, Chen
Publicado 2015

Global impact of aberrant splicing on human gene expression levels

por Fair, Benjamin, Najar, Carlos Buen Abad, Zhao, Junxing, Lozano, Stephanie, Reilly, Austin, Mossian, Gabriela, Staley, Jonathan P, Wang, Jingxin, Li, Yang I
Publicado 2023

RNA catalyzes nuclear pre-mRNA splicing

por Fica, Sebastian M., Tuttle, Nicole, Novak, Thaddeus, Li, Nan-Sheng, Lu, Jun, Koodathingal, Prakash, Dai, Qing, Staley, Jonathan P., Piccirilli, Joseph A.
Publicado 2013

A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation

por Schellenberg, Matthew J., Wu, Tao, Ritchie, Dustin B., Fica, Sebastian, Staley, Jonathan P., Atta, Karim A., LaPointe, Paul, MacMillan, Andrew M.
Publicado 2013

Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs

por Ranoa, Diana Rose E., Parekh, Akash D., Pitroda, Sean P., Huang, Xiaona, Darga, Thomas, Wong, Anthony C., Huang, Lei, Andrade, Jorge, Staley, Jonathan P., Satoh, Takashi, Akira, Shizuo, Weichselbaum, Ralph R., Khodarev, Nikolai N.
Publicado 2016

The debranching enzyme Dbr1 regulates lariat turnover and intron splicing

por Buerer, Luke, Clark, Nathaniel E., Welch, Anastasia, Duan, Chaorui, Taggart, Allison J., Townley, Brittany A., Wang, Jing, Soemedi, Rachel, Rong, Stephen, Lin, Chien-Ling, Zeng, Yi, Katolik, Adam, Staley, Jonathan P., Damha, Masad J., Mosammaparast, Nima, Fairbrother, William G.
Publicado 2023