Both Fasting and Glucose-Stimulated Proinsulin Levels Predict Hyperglycemia and Incident Type 2 Diabetes: A Population-Based Study of 9,396 Finnish Men

por Vangipurapu, Jagadish, Stančáková, Alena, Kuulasmaa, Teemu, Kuusisto, Johanna, Laakso, Markku
Publicado 2015

Finnish Diabetes Risk Score Is Associated with Impaired Insulin Secretion and Insulin Sensitivity, Drug-Treated Hypertension and Cardiovascular Disease: A Follow-Up Study of the ME...

por Fizelova, Maria, Jauhiainen, Raimo, Stančáková, Alena, Kuusisto, Johanna, Laakso, Markku
Publicado 2016

Changes in Insulin Sensitivity and Insulin Release in Relation to Glycemia and Glucose Tolerance in 6,414 Finnish Men

por Stančáková, Alena, Javorský, Martin, Kuulasmaa, Teemu, Haffner, Steven M., Kuusisto, Johanna, Laakso, Markku
Publicado 2009

Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells

por Yaluri, Nagendra, Modi, Shalem, López Rodríguez, Maykel, Stančáková, Alena, Kuusisto, Johanna, Kokkola, Tarja, Laakso, Markku
Publicado 2015

Markers of Tissue-Specific Insulin Resistance Predict the Worsening of Hyperglycemia, Incident Type 2 Diabetes and Cardiovascular Disease

por FízeI'ová, Mária, Cederberg, Henna, Stančáková, Alena, Jauhiainen, Raimo, Vangipurapu, Jagadish, Kuusisto, Johanna, Laakso, Markku
Publicado 2014

Differential Associations of Inflammatory Markers With Insulin Sensitivity and Secretion: The Prospective METSIM Study

por Fizelova, Maria, Jauhiainen, Raimo, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Kuusisto, Johanna, Laakso, Markku, Stančáková, Alena
Publicado 2017

Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men

por Stančáková, Alena, Kuulasmaa, Teemu, Paananen, Jussi, Jackson, Anne U., Bonnycastle, Lori L., Collins, Francis S., Boehnke, Michael, Kuusisto, Johanna, Laakso, Markku
Publicado 2009

Non-Cholesterol Sterol Levels Predict Hyperglycemia and Conversion to Type 2 Diabetes in Finnish Men

por Cederberg, Henna, Gylling, Helena, Miettinen, Tatu A., Paananen, Jussi, Vangipurapu, Jagadish, Pihlajamäki, Jussi, Kuulasmaa, Teemu, Stančáková, Alena, Smith, Ulf, Kuusisto, Johanna, Laakso, Markku
Publicado 2013

Impact of Positive Family History and Genetic Risk Variants on the Incidence of Diabetes: The Finnish Diabetes Prevention Study

por Uusitupa, Matti I., Stančáková, Alena, Peltonen, Markku, Eriksson, Johan G., Lindström, Jaana, Aunola, Sirkka, Ilanne-Parikka, Pirjo, Keinänen-Kiukaanniemi, Sirkka, Tuomilehto, Jaakko, Laakso, Markku
Publicado 2011

The D299G/T399I Toll-Like Receptor 4 Variant Associates with Body and Liver Fat: Results from the TULIP and METSIM Studies

por Weyrich, Peter, Staiger, Harald, Stančáková, Alena, Machicao, Fausto, Machann, Jürgen, Schick, Fritz, Stefan, Norbert, Kuusisto, Johanna, Laakso, Markku, Schäfer, Silke, Fritsche, Andreas, Häring, Hans-Ulrich
Publicado 2010

Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes

por Mardinoglu, Adil, Gogg, Silvia, Lotta, Luca A., Stančáková, Alena, Nerstedt, Annika, Boren, Jan, Blüher, Matthias, Ferrannini, Ele, Langenberg, Claudia, Wareham, Nicholas J., Laakso, Markku, Smith, Ulf
Publicado 2017

Decreased plasma C‐reactive protein levels in APOE ε4 allele carriers

por Martiskainen, Henna, Takalo, Mari, Solomon, Alina, Stančáková, Alena, Marttinen, Mikael, Natunen, Teemu, Haapasalo, Annakaisa, Herukka, Sanna‐Kaisa, Kuusisto, Johanna, Soininen, Hilkka, Kivipelto, Miia, Laakso, Markku, Hiltunen, Mikko
Publicado 2018

Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced β-cell function in non-diabetic subjects

por Weyrich, Peter, Staiger, Harald, Stančáková, Alena, Schäfer, Silke A, Kirchhoff, Kerstin, Ullrich, Susanne, Ranta, Felicia, Gallwitz, Baptist, Stefan, Norbert, Machicao, Fausto, Kuusisto, Johanna, Laakso, Markku, Fritsche, Andreas, Häring, Hans-Ulrich
Publicado 2009

Effects of 34 Risk Loci for Type 2 Diabetes or Hyperglycemia on Lipoprotein Subclasses and Their Composition in 6,580 Nondiabetic Finnish Men

por Stančáková, Alena, Paananen, Jussi, Soininen, Pasi, Kangas, Antti J., Bonnycastle, Lori L., Morken, Mario A., Collins, Francis S., Jackson, Anne U., Boehnke, Michael L., Kuusisto, Johanna, Ala-Korpela, Mika, Laakso, Markku
Publicado 2011

The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge

por Andersson, Ehm A., Harder, Marie N., Pilgaard, Kasper, Pisinger, Charlotta, Stančáková, Alena, Kuusisto, Johanna, Grarup, Niels, Færch, Kristine, Poulsen, Pernille, Witte, Daniel R., Jørgensen, Torben, Vaag, Allan, Laakso, Markku, Pedersen, Oluf, Hansen, Torben
Publicado 2011

Variance of the SGK1 Gene Is Associated with Insulin Secretion in Different European Populations: Results from the TUEF, EUGENE2, and METSIM Studies

por Friedrich, Björn, Weyrich, Peter, Stančáková, Alena, Wang, Jianjung, Kuusisto, Johanna, Laakso, Markku, Sesti, Giorgio, Succurro, Elena, Smith, Ulf, Hansen, Torben, Pedersen, Oluf, Machicao, Fausto, Schäfer, Silke, Lang, Florian, Risler, Teut, Ullrich, Susanne, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich
Publicado 2008

Hyperglycemia and a Common Variant of GCKR Are Associated With the Levels of Eight Amino Acids in 9,369 Finnish Men

por Stančáková, Alena, Civelek, Mete, Saleem, Niyas K., Soininen, Pasi, Kangas, Antti J., Cederberg, Henna, Paananen, Jussi, Pihlajamäki, Jussi, Bonnycastle, Lori L., Morken, Mario A., Boehnke, Michael, Pajukanta, Päivi, Lusis, Aldons J., Collins, Francis S., Kuusisto, Johanna, Ala-Korpela, Mika, Laakso, Markku
Publicado 2012

Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance

por Patel, Kashyap A., Kettunen, Jarno, Laakso, Markku, Stančáková, Alena, Laver, Thomas W., Colclough, Kevin, Johnson, Matthew B., Abramowicz, Marc, Groop, Leif, Miettinen, Päivi J., Shepherd, Maggie H., Flanagan, Sarah E., Ellard, Sian, Inagaki, Nobuya, Hattersley, Andrew T., Tuomi, Tiinamaija, Cnop, Miriam, Weedon, Michael N.
Publicado 2017

Association of Ketone Body Levels With Hyperglycemia and Type 2 Diabetes in 9,398 Finnish Men

por Mahendran, Yuvaraj, Vangipurapu, Jagadish, Cederberg, Henna, Stančáková, Alena, Pihlajamäki, Jussi, Soininen, Pasi, Kangas, Antti J., Paananen, Jussi, Civelek, Mete, Saleem, Niyas K., Pajukanta, Päivi, Lusis, Aldons J., Bonnycastle, Lori L., Morken, Mario A., Collins, Francis S., Mohlke, Karen L., Boehnke, Michael, Ala-Korpela, Mika, Kuusisto, Johanna, Laakso, Markku
Publicado 2013

Link Between GIP and Osteopontin in Adipose Tissue and Insulin Resistance

por Ahlqvist, Emma, Osmark, Peter, Kuulasmaa, Tiina, Pilgaard, Kasper, Omar, Bilal, Brøns, Charlotte, Kotova, Olga, Zetterqvist, Anna V., Stančáková, Alena, Jonsson, Anna, Hansson, Ola, Kuusisto, Johanna, Kieffer, Timothy J., Tuomi, Tiinamaija, Isomaa, Bo, Madsbad, Sten, Gomez, Maria F., Poulsen, Pernille, Laakso, Markku, Degerman, Eva, Pihlajamäki, Jussi, Wierup, Nils, Vaag, Allan, Groop, Leif, Lyssenko, Valeriya
Publicado 2013