Three-Dimensional Patient-Derived In Vitro Sarcoma Models: Promising Tools for Improving Clinical Tumor Management

por Gaebler, Manuela, Silvestri, Alessandra, Haybaeck, Johannes, Reichardt, Peter, Lowery, Caitlin D., Stancato, Louis F., Zybarth, Gabriele, Regenbrecht, Christian R. A.
Publicado 2017

Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy

por Lowery, Caitlin D., Blosser, Wayne, Dowless, Michele, Renschler, Matthew, Perez, Lisa V., Stephens, Jennifer, Pytowski, Bronislaw, Wasserstrom, Heather, Stancato, Louis F., Falcon, Beverly
Publicado 2019

LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer

por Vakana, Eliza, Pratt, Susan, Blosser, Wayne, Dowless, Michele, Simpson, Nicholas, Yuan, Xiu-Juan, Jaken, Susan, Manro, Jason, Stephens, Jennifer, Zhang, Youyan, Huber, Lysiane, Peng, Sheng-Bin, Stancato, Louis F.
Publicado 2016

Inhibition of CXCR4 by LY2624587, a Fully Humanized Anti-CXCR4 Antibody Induces Apoptosis of Hematologic Malignancies

por Peng, Sheng-Bin, Zhang, Xiaoyi, Paul, Donald, Kays, Lisa M., Ye, Ming, Vaillancourt, Peter, Dowless, Michele, Stancato, Louis F., Stewart, Julie, Uhlik, Mark T., Long, Haiyan, Chu, Shaoyou, Obungu, Victor H.
Publicado 2016

Systematic target actionability reviews of preclinical proof-of-concept papers to match targeted drugs to paediatric cancers

por Schubert, Nil A., Lowery, Caitlin D., Bergthold, Guillaume, Koster, Jan, Eleveld, Thomas F., Rodríguez, Ana, Jones, David T.W., Vassal, Gilles, Stancato, Louis F., Pfister, Stefan M., Caron, Hubert N., Molenaar, Jan J.
Publicado 2020

Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant

por Veschi, Veronica, Mangiapane, Laura R., Nicotra, Annalisa, Di Franco, Simone, Scavo, Emanuela, Apuzzo, Tiziana, Sardina, Davide S., Fiori, Micol, Benfante, Antonina, Colorito, Maria L., Cocorullo, Gianfranco, Giuliante, Felice, Cipolla, Calogero, Pistone, Giuseppe, Bongiorno, Maria Rita, Rizzo, Aroldo, Tate, Courtney M., Wu, Xiaohua, Rowlinson, Scott, Stancato, Louis F., Todaro, Matilde, De Maria, Ruggero, Stassi, Giorgio
Publicado 2019

RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies

por Solomon, Benjamin J., Tan, Lavinia, Lin, Jessica J., Wong, Stephen Q., Hollizeck, Sebastian, Ebata, Kevin, Tuch, Brian B., Yoda, Satoshi, Gainor, Justin F., Sequist, Lecia V., Oxnard, Geoffrey R., Gautschi, Oliver, Drilon, Alexander, Subbiah, Vivek, Khoo, Christine, Zhu, Edward Y., Nguyen, Michele, Henry, Dahlia, Condroski, Kevin R., Kolakowski, Gabrielle R., Gomez, Eliana, Ballard, Joshua, Metcalf, Andrew T., Blake, James F., Dawson, Sarah-Jane, Blosser, Wayne, Stancato, Louis F., Brandhuber, Barbara J., Andrews, Steve, Robinson, Bruce G., Rothenberg, S. Michael
Publicado 2020