Pioneer factors in development and cancer

por Sunkel, Benjamin D., Stanton, Benjamin Z.
Publicado 2021

Chromatin structure in cancer

por Wang, Meng, Sunkel, Benjamin D., Ray, William C., Stanton, Benjamin Z.
Publicado 2022

The 3D chromatin landscape of rhabdomyosarcoma

por Wang, Meng, Sreenivas, Prethish, Sunkel, Benjamin D, Wang, Long, Ignatius, Myron, Stanton, Benjamin Z
Publicado 2023

Discovery of Small-Molecule Modulators of the Sonic Hedgehog Pathway

por Schaefer, Giannina I., Perez, José R., Duvall, Jeremy R., Stanton, Benjamin Z., Shamji, Alykhan F., Schreiber, Stuart L.
Publicado 2013

Evidence of pioneer factor activity of an oncogenic fusion transcription factor

por Sunkel, Benjamin D., Wang, Meng, LaHaye, Stephanie, Kelly, Benjamin J., Fitch, James R., Barr, Frederic G., White, Peter, Stanton, Benjamin Z.
Publicado 2021

Epigenetic regulation of nuclear lamina-associated heterochromatin by HAT1 and the acetylation of newly synthesized histones

por Popova, Liudmila V, Nagarajan, Prabakaran, Lovejoy, Callie M, Sunkel, Benjamin D, Gardner, Miranda L, Wang, Meng, Freitas, Michael A, Stanton, Benjamin Z, Parthun, Mark R
Publicado 2021

Dominant-negative SMARCA4 missense mutations alter the accessibility landscape of tissue-unrestricted enhancers

por Hodges, H. Courtney, Stanton, Benjamin Z., Cermakova, Katerina, Chang, Chiung-Ying, Miller, Erik L., Kirkland, Jacob G., Ku, Wai Lim, Veverka, Vaclav, Zhao, Keji, Crabtree, Gerald R.
Publicado 2017

The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma

por Boone, Megann A., Taslim, Cenny, Crow, Jesse C., Selich-Anderson, Julia, Byrum, Andrea K., Showpnil, Iftekhar A., Sunkel, Benjamin D., Wang, Meng, Stanton, Benjamin Z., Theisen, Emily R., Lessnick, Stephen L.
Publicado 2021

Miswired Enhancer Logic Drives a Cancer of the Muscle Lineage

por Gryder, Berkley E., Wachtel, Marco, Chang, Kenneth, El Demerdash, Osama, Aboreden, Nicholas G., Mohammed, Wardah, Ewert, Winston, Pomella, Silvia, Rota, Rossella, Wei, Jun S., Song, Young, Stanton, Benjamin Z., Schäfer, Beat, Vakoc, Christopher R., Khan, Javed
Publicado 2020

Chemical genomics reveals histone deacetylases are required for core regulatory transcription

por Gryder, Berkley E., Wu, Lei, Woldemichael, Girma M., Pomella, Silvia, Quinn, Taylor R., Park, Paul M. C., Cleveland, Abigail, Stanton, Benjamin Z., Song, Young, Rota, Rossella, Wiest, Olaf, Yohe, Marielle E., Shern, Jack F., Qi, Jun, Khan, Javed
Publicado 2019

A small molecule that binds Hedgehog and blocks its signaling in human cells

por Stanton, Benjamin Z., Peng, Lee F., Maloof, Nicole, Nakai, Kazuo, Wang, Xiang, Herlihy, Kara M., Duffner, Jay L., Taveras, Kennedy M., Hyman, Joel M., Lee, Sam W., Koehler, Angela N., Chen, James K., Fox, Julia L., Mandinova, Anna, Schreiber, Stuart L.
Publicado 2009

Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma

por Gryder, Berkley E., Pomella, Silvia, Sayers, Carly, Wu, Xiaoli S., Song, Young, Chiarella, Anna M., Bagchi, Sukriti, Chou, Hsien-Chao, Sinniah, Ranu S., Walton, Ashley, Wen, Xinyu, Rota, Rossella, Hathaway, Nathaniel A., Zhao, Keji, Chen, Jiji, Vakoc, Christopher R., Shern, Jack F., Stanton, Benjamin Z., Khan, Javed
Publicado 2019

Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies

por Dockendorff, Chris, Nagiec, Marek M., Weïwer, Michel, Buhrlage, Sara, Ting, Amal, Nag, Partha P., Germain, Andrew, Kim, Han-Je, Youngsaye, Willmen, Scherer, Christina, Bennion, Melissa, Xue, Linlong, Stanton, Benjamin Z., Lewis, Timothy A., MacPherson, Lawrence, Palmer, Michelle, Foley, Michael A., Perez, José R., Schreiber, Stuart L.
Publicado 2012

BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma

por Laubscher, Dominik, Gryder, Berkley E., Sunkel, Benjamin D., Andresson, Thorkell, Wachtel, Marco, Das, Sudipto, Roschitzki, Bernd, Wolski, Witold, Wu, Xiaoli S., Chou, Hsien-Chao, Song, Young K., Wang, Chaoyu, Wei, Jun S., Wang, Meng, Wen, Xinyu, Ngo, Quy Ai, Marques, Joana G., Vakoc, Christopher R., Schäfer, Beat W., Stanton, Benjamin Z., Khan, Javed
Publicado 2021

Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma

por Pomella, Silvia, Sreenivas, Prethish, Gryder, Berkley E., Wang, Long, Milewski, David, Cassandri, Matteo, Baxi, Kunal, Hensch, Nicole R., Carcarino, Elena, Song, Young, Chou, Hsien-Chao, Yohe, Marielle E., Stanton, Benjamin Z., Amadio, Bruno, Caruana, Ignazio, De Stefanis, Cristiano, De Vito, Rita, Locatelli, Franco, Chen, Yidong, Chen, Eleanor Y., Houghton, Peter, Khan, Javed, Rota, Rossella, Ignatius, Myron S.
Publicado 2021

A stem cell epigenome is associated with primary nonresponse to CD19 CAR T cells in pediatric acute lymphoblastic leukemia

por Masih, Katherine E., Gardner, Rebecca A., Chou, Hsien-Chao, Abdelmaksoud, Abdalla, Song, Young K., Mariani, Luca, Gangalapudi, Vineela, Gryder, Berkley E., Wilson, Ashley L., Adebola, Serifat O., Stanton, Benjamin Z., Wang, Chaoyu, Milewski, David, Kim, Yong Yean, Tian, Meijie, Cheuk, Adam Tai-Chi, Wen, Xinyu, Zhang, Yue, Altan-Bonnet, Grégoire, Kelly, Michael C., Wei, Jun S., Bulyk, Martha L., Jensen, Michael C., Orentas, Rimas J., Khan, Javed
Publicado 2023