Deep mutational scans of XBB.1.5 and BQ.1.1 reveal ongoing epistatic drift during SARS-CoV-2 evolution

por Taylor, Ashley L., Starr, Tyler N.
Publicado 2023

Alternate evolutionary histories in the sequence space of an ancient protein

por Starr, Tyler N., Picton, Lora K., Thornton, Joseph W.
Publicado 2017

An antibody-escape calculator for mutations to the SARS-CoV-2 receptor-binding domain

por Greaney, Allison J., Starr, Tyler N., Bloom, Jesse D.
Publicado 2021

An antibody-escape estimator for mutations to the SARS-CoV-2 receptor-binding domain

por Greaney, Allison J, Starr, Tyler N, Bloom, Jesse D
Publicado 2022

Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016

por Starr, Tyler N., Greaney, Allison J., Dingens, Adam S., Bloom, Jesse D.
Publicado 2021

Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016

por Starr, Tyler N., Greaney, Allison J., Dingens, Adam S., Bloom, Jesse D.
Publicado 2021

ACE2 binding is an ancestral and evolvable trait of sarbecoviruses

por Starr, Tyler N., Zepeda, Samantha K., Walls, Alexandra C., Greaney, Allison J., Alkhovsky, Sergey, Veesler, David, Bloom, Jesse D.
Publicado 2022

Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

por Starr, Tyler N., Greaney, Allison J., Stewart, Cameron M., Walls, Alexandra C., Hannon, William W., Veesler, David, Bloom, Jesse D.
Publicado 2022

Prospective mapping of viral mutations that escape antibodies used to treat COVID-19

por Starr, Tyler N., Greaney, Allison J., Addetia, Amin, Hannon, William W., Choudhary, Manish C., Dingens, Adam S., Li, Jonathan Z., Bloom, Jesse D.
Publicado 2020

Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies

por Greaney, Allison J., Loes, Andrea N., Crawford, Katharine H.D., Starr, Tyler N., Malone, Keara D., Chu, Helen Y., Bloom, Jesse D.
Publicado 2021

Prospective mapping of viral mutations that escape antibodies used to treat COVID-19

por Starr, Tyler N., Greaney, Allison J., Addetia, Amin, Hannon, William W., Choudhary, Manish C., Dingens, Adam S., Li, Jonathan Z., Bloom, Jesse D.
Publicado 2021

The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution

por Moulana, Alief, Dupic, Thomas, Phillips, Angela M, Chang, Jeffrey, Roffler, Anne A, Greaney, Allison J, Starr, Tyler N, Bloom, Jesse D, Desai, Michael M
Publicado 2023

The SARS-CoV-2 mRNA-1273 vaccine elicits more RBD-focused neutralization, but with broader antibody binding within the RBD

por Greaney, Allison J., Loes, Andrea N., Gentles, Lauren E., Crawford, Katharine H.D., Starr, Tyler N., Malone, Keara D., Chu, Helen Y., Bloom, Jesse D.
Publicado 2021

Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection

por Greaney, Allison J., Loes, Andrea N., Gentles, Lauren E., Crawford, Katharine H.D., Starr, Tyler N., Malone, Keara D., Chu, Helen Y., Bloom, Jesse D.
Publicado 2021

Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1

por Moulana, Alief, Dupic, Thomas, Phillips, Angela M., Chang, Jeffrey, Nieves, Serafina, Roffler, Anne A., Greaney, Allison J., Starr, Tyler N., Bloom, Jesse D., Desai, Michael M.
Publicado 2022

The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes

por Greaney, Allison J., Eguia, Rachel T., Starr, Tyler N., Khan, Khadija, Franko, Nicholas, Logue, Jennifer K., Lord, Sandra M., Speake, Cate, Chu, Helen Y., Sigal, Alex, Bloom, Jesse D.
Publicado 2022

The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes

por Greaney, Allison J., Eguia, Rachel T., Starr, Tyler N., Khan, Khadija, Franko, Nicholas, Logue, Jennifer K., Lord, Sandra M., Speake, Cate, Chu, Helen Y., Sigal, Alex, Bloom, Jesse D.
Publicado 2022

Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus

por Lee, Jimin, Zepeda, Samantha K., Park, Young-Jun, Taylor, Ashley L., Quispe, Joel, Stewart, Cameron, Leaf, Elizabeth M., Treichel, Catherine, Corti, Davide, King, Neil P., Starr, Tyler N., Veesler, David
Publicado 2023

Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding

por Starr, Tyler N., Greaney, Allison J., Hilton, Sarah K., Crawford, Katharine H.D., Navarro, Mary Jane, Bowen, John E., Tortorici, M. Alejandra, Walls, Alexandra C., Veesler, David, Bloom, Jesse D.
Publicado 2020

Evolution of antibody immunity following Omicron BA.1 breakthrough infection

por Kaku, Chengzi I., Starr, Tyler N., Zhou, Panpan, Dugan, Haley L., Khalifé, Paul, Song, Ge, Champney, Elizabeth R., Mielcarz, Daniel W., Geoghegan, James C., Burton, Dennis R., Andrabi, Raiees, Bloom, Jesse D., Walker, Laura M.
Publicado 2023