SAHA overcomes FLIP-mediated inhibition of SMAC mimetic-induced apoptosis in mesothelioma

por Crawford, N, Stasik, I, Holohan, C, Majkut, J, McGrath, M, Johnston, P G, Chessari, G, Ward, G A, Waugh, D J, Fennell, D A, Longley, D B
Publicado 2013

Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer

por Paul, I, Chacko, A D, Stasik, I, Busacca, S, Crawford, N, McCoy, F, McTavish, N, Wilson, B, Barr, M, O'Byrne, K J, Longley, D B, Fennell, D A
Publicado 2012

Differential affinity of FLIP and procaspase 8 for FADD’s DED binding surfaces regulates DISC assembly

por Majkut, J, Sgobba, M, Holohan, C, Crawford, N, Logan, AE, Kerr, E, Higgins, CA, Redmond, KL, Riley, JS, Stasik, I, Fennell, DA, Van Schaeybroeck, S, Haider, S, Johnston, PG, Haigh, D, Longley, DB
Publicado 2014

Prognostic and therapeutic relevance of FLIP and procaspase-8 overexpression in non-small cell lung cancer

por Riley, J S, Hutchinson, R, McArt, D G, Crawford, N, Holohan, C, Paul, I, Van Schaeybroeck, S, Salto-Tellez, M, Johnston, P G, Fennell, D A, Gately, K, O'Byrne, K, Cummins, R, Kay, E, Hamilton, P, Stasik, I, Longley, D B
Publicado 2013