Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase

por Chen, Chun-Liang, Paul, Lake N., Mermoud, James C., Steussy, Calvin Nicklaus, Stauffacher, Cynthia V.
Publicado 2020

Biochemical characterization of essential cell division proteins FtsX and FtsE that mediate peptidoglycan hydrolysis by PcsB in Streptococcus pneumoniae

por Bajaj, Ruchika, Bruce, Kevin E., Davidson, Amy L., Rued, Britta E., Stauffacher, Cynthia V., Winkler, Malcolm E.
Publicado 2016

The nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner

por Jayaraman, Swaathi, Chittiboyina, Shirisha, Bai, Yunfeng, Abad, Patricia C., Vidi, Pierre-Alexandre, Stauffacher, Cynthia V., Lelièvre, Sophie A.
Publicado 2017

Targeting Enterococcus faecalis HMG-CoA reductase with a non-statin inhibitor

por Bose, Sucharita, Steussy, C. Nicklaus, López-Pérez, Daneli, Schmidt, Tim, Kulathunga, Samadhi C., Seleem, Mohamed N., Lipton, Mark, Mesecar, Andrew D., Rodwell, Victor W., Stauffacher, Cynthia V.
Publicado 2023

Microsecond timescale MD simulations at the transition state of PmHMGR predict remote allosteric residues

por Quinn, Taylor R., Steussy, Calvin N., Haines, Brandon E., Lei, Jinping, Wang, Wei, Sheong, Fu Kit, Stauffacher, Cynthia V., Huang, Xuhui, Norrby, Per-Ola, Helquist, Paul, Wiest, Olaf
Publicado 2021

Heterogeneity in Lowe Syndrome: Mutations Affecting the Phosphatase Domain of OCRL1 Differ in Impact on Enzymatic Activity and Severity of Cellular Phenotypes

por Lee, Jennifer J., Ramadesikan, Swetha, Black, Adrianna F., Christoffer, Charles, Pacheco, Andres F. Pacheco, Subramanian, Sneha, Hanna, Claudia B., Barth, Gillian, Stauffacher, Cynthia V., Kihara, Daisuke, Aguilar, Ruben Claudio
Publicado 2023