Turn to TCRs when CARs fail

por Stauss, Hans J.
Publicado 2017

Engineering CD4+ T Cells to Enhance Cancer Immunity

por Sillito, Francesca, Holler, Angelika, Stauss, Hans J.
Publicado 2020

TCR Gene Therapy: Challenges, Opportunities, and Future Directions

por Stauss, Hans J., Tran, Maxine G. B.
Publicado 2020

Synthetic Cell-Based Immunotherapies for Neurologic Diseases

por von Baumgarten, Louisa, Stauss, Hans J., Lünemann, Jan D.
Publicado 2023

Forced Fox-P3 expression can improve the safety and antigen-specific function of engineered regulatory T cells

por McGovern, Jenny, Holler, Angelika, Thomas, Sharyn, Stauss, Hans J.
Publicado 2022

A Study of T Cell Tolerance to the Tumor-Associated Antigen MDM2: Cytokines Can Restore Antigen Responsiveness, but Not High Avidity T Cell Function

por Bendle, Gavin M., Xue, Shao-An, Holler, Angelika, Stauss, Hans J.
Publicado 2007

Engineering Specificity and Function of Therapeutic Regulatory T Cells

por McGovern, Jenny L., Wright, Graham P., Stauss, Hans J.
Publicado 2017

Safety and efficacy of Tet-regulated IL-12 expression in cancer-specific T cells

por Alsaieedi, Ahdab, Holler, Angelika, Velica, Pedro, Bendle, Gavin, Stauss, Hans J.
Publicado 2018

Modifications outside CDR1, 2 and 3 of the TCR variable β domain increase TCR expression and antigen-specific function

por Degirmencay, Abdullah, Thomas, Sharyn, Mohammed, Fiyaz, Willcox, Benjamin E., Stauss, Hans J.
Publicado 2023

Tumor-Resident Dendritic Cells and Macrophages Modulate the Accumulation of TCR-Engineered T Cells in Melanoma

por Hotblack, Alastair, Holler, Angelika, Piapi, Alice, Ward, Sophie, Stauss, Hans J., Bennett, Clare L.
Publicado 2018

Differences in systemic adaptive immunity contribute to the ‘frequent exacerbator’ COPD phenotype

por Geerdink, Jasper X., Simons, Sami O., Pike, Rebecca, Stauss, Hans J., Heijdra, Yvonne F., Hurst, John R.
Publicado 2016

Graft-versus-host disease reduces lymph node display of tissue-restricted self-antigens and promotes autoimmunity

por Dertschnig, Simone, Evans, Pamela, Santos e Sousa, Pedro, Manzo, Teresa, Ferrer, Ivana R., Stauss, Hans J., Bennett, Clare L., Chakraverty, Ronjon
Publicado 2020

PD1-Expressing T Cell Subsets Modify the Rejection Risk in Renal Transplant Patients

por Pike, Rebecca, Thomas, Niclas, Workman, Sarita, Ambrose, Lyn, Guzman, David, Sivakumaran, Shivajanani, Johnson, Margaret, Thorburn, Douglas, Harber, Mark, Chain, Benny, Stauss, Hans J.
Publicado 2016

Human MHC Class I-restricted high avidity CD4(+) T cells generated by co-transfer of TCR and CD8 mediate efficient tumor rejection in vivo

por Xue, Shao-An, Gao, Liquan, Ahmadi, Maryam, Ghorashian, Sara, Barros, Rafael D, Pospori, Constandina, Holler, Angelika, Wright, Graham, Thomas, Sharyn, Topp, Max, Morris, Emma C, Stauss, Hans J.
Publicado 2013

CD8 T Cell Tolerance to a Tumor-Associated Self-Antigen Is Reversed by CD4 T Cells Engineered To Express the Same T Cell Receptor

por Ghorashian, Sara, Veliça, Pedro, Chua, Ignatius, McNicol, Anne-Marie, Carpenter, Ben, Holler, Angelika, Nicholson, Emma, Ahmadi, Maryam, Zech, Mathias, Xue, Shao-An, Uckert, Wolfgang, Morris, Emma, Chakraverty, Ronjon, Stauss, Hans J.
Publicado 2015

Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function

por Thomas, Sharyn, Mohammed, Fiyaz, Reijmers, Rogier M., Woolston, Annemarie, Stauss, Theresa, Kennedy, Alan, Stirling, David, Holler, Angelika, Green, Louisa, Jones, David, Matthews, Katherine K., Price, David A., Chain, Benjamin M., Heemskerk, Mirjam H. M., Morris, Emma C., Willcox, Benjamin E., Stauss, Hans J.
Publicado 2019

Molecular Recalibration of PD-1+ Antigen-Specific T Cells from Blood and Liver

por Otano, Itziar, Escors, David, Schurich, Anna, Singh, Harsimran, Robertson, Francis, Davidson, Brian R., Fusai, Giuseppe, Vargas, Frederick A., Tan, Zhi M.D., Aw, Jia Y.J., Hansi, Navjyot, Kennedy, Patrick T.F., Xue, Shao-An, Stauss, Hans J., Bertoletti, Antonio, Pavesi, Andrea, Maini, Mala K.
Publicado 2018

The effect of spike mutations on SARS-CoV-2 neutralization

por Rees-Spear, Chloe, Muir, Luke, Griffith, Sarah A., Heaney, Judith, Aldon, Yoann, Snitselaar, Jonne L., Thomas, Peter, Graham, Carl, Seow, Jeffrey, Lee, Nayung, Rosa, Annachiara, Roustan, Chloe, Houlihan, Catherine F., Sanders, Rogier W., Gupta, Ravindra K., Cherepanov, Peter, Stauss, Hans J., Nastouli, Eleni, Doores, Katie J., van Gils, Marit J., McCoy, Laura E.
Publicado 2021

Reconstitution of a functional human thymus by postnatal stromal progenitor cells and natural whole-organ scaffolds

por Campinoti, Sara, Gjinovci, Asllan, Ragazzini, Roberta, Zanieri, Luca, Ariza-McNaughton, Linda, Catucci, Marco, Boeing, Stefan, Park, Jong-Eun, Hutchinson, John C., Muñoz-Ruiz, Miguel, Manti, Pierluigi G., Vozza, Gianluca, Villa, Carlo E., Phylactopoulos, Demetra-Ellie, Maurer, Constance, Testa, Giuseppe, Stauss, Hans J., Teichmann, Sarah A., Sebire, Neil J., Hayday, Adrian C., Bonnet, Dominique, Bonfanti, Paola
Publicado 2020

Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint

por Schmidt, Nathalie M., Wing, Peter A. C., Diniz, Mariana O., Pallett, Laura J., Swadling, Leo, Harris, James M., Burton, Alice R., Jeffery-Smith, Anna, Zakeri, Nekisa, Amin, Oliver E., Kucykowicz, Stephanie, Heemskerk, Mirjam H., Davidson, Brian, Meyer, Tim, Grove, Joe, Stauss, Hans J., Pineda-Torra, Ines, Jolly, Clare, Jury, Elizabeth C., McKeating, Jane A., Maini, Mala K.
Publicado 2021