Dopamine D(2) Receptor Agonist Binding Kinetics—Role of a Conserved Serine Residue

por Ågren, Richard, Stepniewski, Tomasz Maciej, Zeberg, Hugo, Selent, Jana, Sahlholm, Kristoffer
Publicado 2021

How Do Molecular Dynamics Data Complement Static Structural Data of GPCRs

por Torrens-Fontanals, Mariona, Stepniewski, Tomasz Maciej, Aranda-García, David, Morales-Pastor, Adrián, Medel-Lacruz, Brian, Selent, Jana
Publicado 2020

A molecular sensor for cholesterol in the human serotonin(1A) receptor

por Kumar, G. Aditya, Sarkar, Parijat, Stepniewski, Tomasz Maciej, Jafurulla, Md., Singh, Shishu Pal, Selent, Jana, Chattopadhyay, Amitabha
Publicado 2021

Mechanistic insights into dopaminergic and serotonergic neurotransmission – concerted interactions with helices 5 and 6 drive the functional outcome

por Stepniewski, Tomasz Maciej, Mancini, Arturo, Ågren, Richard, Torrens-Fontanals, Mariona, Semache, Meriem, Bouvier, Michel, Sahlholm, Kristoffer, Breton, Billy, Selent, Jana
Publicado 2021

Ligand entry pathways control the chemical space recognized by GPR183

por Kjær, Viktoria Madeline Skovgaard, Stępniewski, Tomasz Maciej, Medel-Lacruz, Brian, Reinmuth, Lisa, Ciba, Marija, Rexen Ulven, Elisabeth, Bonomi, Massimiliano, Selent, Jana, Rosenkilde, Mette Marie
Publicado 2023

Distinct phosphorylation sites in a prototypical GPCR differently orchestrate β-arrestin interaction, trafficking, and signaling

por Dwivedi-Agnihotri, Hemlata, Chaturvedi, Madhu, Baidya, Mithu, Stepniewski, Tomasz Maciej, Pandey, Shubhi, Maharana, Jagannath, Srivastava, Ashish, Caengprasath, Natarin, Hanyaloglu, Aylin C., Selent, Jana, Shukla, Arun K.
Publicado 2020

Entrectinib—A SARS-CoV-2 Inhibitor in Human Lung Tissue (HLT) Cells

por Peralta-Garcia, Alejandro, Torrens-Fontanals, Mariona, Stepniewski, Tomasz Maciej, Grau-Expósito, Judith, Perea, David, Ayinampudi, Vikram, Waldhoer, Maria, Zimmermann, Mirjam, Buzón, María J., Genescà, Meritxell, Selent, Jana
Publicado 2021

Ligand with Two Modes of Interaction with the Dopamine D(2) Receptor–An Induced-Fit Mechanism of Insurmountable Antagonism

por Ågren, Richard, Zeberg, Hugo, Stępniewski, Tomasz Maciej, Free, R. Benjamin, Reilly, Sean W., Luedtke, Robert R., Århem, Peter, Ciruela, Francisco, Sibley, David R., Mach, Robert H., Selent, Jana, Nilsson, Johanna, Sahlholm, Kristoffer
Publicado 2020

Development of Fluorescent Probes that Target Serotonin 5-HT(2B) Receptors

por Azuaje, Jhonny, López, Paula, Iglesias, Alba, de la Fuente, Rocío A., Pérez-Rubio, José M., García, Diego, Stępniewski, Tomasz Maciej, García-Mera, Xerardo, Brea, José M., Selent, Jana, Pérez, Dolores, Castro, Marián, Loza, María I., Sotelo, Eddy
Publicado 2017

Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody

por Baidya, Mithu, Chaturvedi, Madhu, Dwivedi-Agnihotri, Hemlata, Ranjan, Ashutosh, Devost, Dominic, Namkung, Yoon, Stepniewski, Tomasz Maciej, Pandey, Shubhi, Baruah, Minakshi, Panigrahi, Bhanupriya, Sarma, Parishmita, Yadav, Manish K., Maharana, Jagannath, Banerjee, Ramanuj, Kawakami, Kouki, Inoue, Asuka, Selent, Jana, Laporte, Stéphane A., Hébert, Terence E., Shukla, Arun K.
Publicado 2022

Phosphorylation barcodes direct biased chemokine signaling at CXCR3

por Eiger, Dylan S., Smith, Jeffrey S., Shi, Tujin, Stepniewski, Tomasz Maciej, Tsai, Chia-Feng, Honeycutt, Christopher, Boldizsar, Noelia, Gardner, Julia, Nicora, Carrie D., Moghieb, Ahmed M., Kawakami, Kouki, Choi, Issac, Zheng, Kevin, Warman, Anmol, Alagesan, Priya, Knape, Nicole M., Huang, Ouwen, Silverman, Justin D., Smith, Richard D., Inoue, Asuka, Selent, Jana, Jacobs, Jon M., Rajagopal, Sudarshan
Publicado 2023