Using common variants to indicate cancer genes

por Stead, Lucy F, Thygesen, Helene, Westhead, David R, Rabbitts, Pamela
Publicado 2015

Simulation of heterogeneous tumour genomes with HeteroGenesis and in silico whole exome sequencing

por Tanner, Georgette, Westhead, David R, Droop, Alastair, Stead, Lucy F
Publicado 2019

Benchmarking pipelines for subclonal deconvolution of bulk tumour sequencing data

por Tanner, Georgette, Westhead, David R., Droop, Alastair, Stead, Lucy F.
Publicado 2021

SpheroidAnalyseR—an online platform for analyzing data from 3D spheroids or organoids grown in 96-well plates

por Barrow, Rhiannon, Wilkinson, Joseph N., He, Yichen, Callaghan, Martin, Brüning-Richardson, Anke, Dunning, Mark, Stead, Lucy F.
Publicado 2022

Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq

por Conway, Caroline, Graham, Jennifer L., Chengot, Preetha, Daly, Catherine, Chalkley, Rebecca, Ross, Lisa, Droop, Alastair, Rabbitts, Pamela, Stead, Lucy F.
Publicado 2015

Identification of candidate mediators of chemoresponse in breast cancer through therapy-driven selection of somatic variants

por Al Amri, Waleed S., Baxter, Diana E., Hanby, Andrew M., Stead, Lucy F., Verghese, Eldo T., Thorne, James L., Hughes, Thomas A.
Publicado 2020

An Integrated Inspection of the Somatic Mutations in a Lung Squamous Cell Carcinoma Using Next-Generation Sequencing

por Stead, Lucy F., Egan, Philip, Devery, Aoife, Conway, Caroline, Daly, Catherine, Berri, Stefano, Wood, Henry, Belvedere, Ornella, Papagiannopoulos, Kostas, Ryan, Anderson, Rabbitts, Pamela
Publicado 2013

RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells

por King, Harry O., Brend, Tim, Payne, Helen L., Wright, Alexander, Ward, Thomas A., Patel, Karan, Egnuni, Teklu, Stead, Lucy F., Patel, Anjana, Wurdak, Heiko, Short, Susan C.
Publicado 2017

Down-Regulation of miR-92 in Breast Epithelial Cells and in Normal but Not Tumour Fibroblasts Contributes to Breast Carcinogenesis

por Smith, Laura, Baxter, Euan W., Chambers, Philip A., Green, Caroline A., Hanby, Andrew M., Hughes, Thomas A., Nash, Claire E., Millican-Slater, Rebecca A., Stead, Lucy F., Verghese, Eldo T., Speirs, Valerie
Publicado 2015

OMRT-3. Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment

por Varn, Frederick, Johnson, Kevin, Barthel, Floris, Kim, Hoon, Wade, Taylor, Malta, Tathiane, Sabedot, Thais, Lodha, Disha, Ajaib, Shoaib, Ahmed, Nazia, Garofano, Luciano, D’Angelo, Fulvio, Stead, Lucy, Poisson, Laila, Noushmehr, Houtan, Iavarone, Antonio, Verhaak, Roel
Publicado 2021

GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data

por Ajaib, Shoaib, Lodha, Disha, Pollock, Steven, Hemmings, Gemma, Finetti, Martina A, Gusnanto, Arief, Chakrabarty, Aruna, Ismail, Azzam, Wilson, Erica, Varn, Frederick S, Hunter, Bethany, Filby, Andrew, Brockman, Asa A, McDonald, David, Verhaak, Roel G W, Ihrie, Rebecca A, Stead, Lucy F
Publicado 2023

Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases

por Webster, Peter J., Littlejohns, Anna T., Gaunt, Hannah J., Young, Richard S., Rode, Baptiste, Ritchie, Judith E., Stead, Lucy F., Harrison, Sally, Droop, Alastair, Martin, Heather L., Tomlinson, Darren C., Hyman, Adam J., Appleby, Hollie L., Boxall, Sally, Bruns, Alexander F., Li, Jing, Prasad, Raj K., Lodge, J. Peter A., Burke, Dermot A., Beech, David J.
Publicado 2017

EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma

por Struve, Nina, Binder, Zev A., Stead, Lucy F., Brend, Tim, Bagley, Stephen J., Faulkner, Claire, Ott, Leonie, Müller-Goebel, Justus, Weik, Anna-Sophie, Hoffer, Konstantin, Krug, Leonie, Rieckmann, Thorsten, Bußmann, Lara, Henze, Marvin, Morrissette, Jennifer J. D., Kurian, Kathreena M., Schüller, Ulrich, Petersen, Cordula, Rothkamm, Kai, O´ Rourke, Donald M., Short, Susan C., Kriegs, Malte
Publicado 2020

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology

por Golebiewska, Anna, Hau, Ann-Christin, Oudin, Anaïs, Stieber, Daniel, Yabo, Yahaya A., Baus, Virginie, Barthelemy, Vanessa, Klein, Eliane, Bougnaud, Sébastien, Keunen, Olivier, Wantz, May, Michelucci, Alessandro, Neirinckx, Virginie, Muller, Arnaud, Kaoma, Tony, Nazarov, Petr V., Azuaje, Francisco, De Falco, Alfonso, Flies, Ben, Richart, Lorraine, Poovathingal, Suresh, Arns, Thais, Grzyb, Kamil, Mock, Andreas, Herold-Mende, Christel, Steino, Anne, Brown, Dennis, May, Patrick, Miletic, Hrvoje, Malta, Tathiane M., Noushmehr, Houtan, Kwon, Yong-Jun, Jahn, Winnie, Klink, Barbara, Tanner, Georgette, Stead, Lucy F., Mittelbronn, Michel, Skupin, Alexander, Hertel, Frank, Bjerkvig, Rolf, Niclou, Simone P.
Publicado 2020

LONGITUDINAL MOLECULAR TRAJECTORIES OF DIFFUSE GLIOMA IN ADULTS

por Barthel, Floris P., Johnson, Kevin C., Varn, Frederick S., Moskalik, Anzhela D., Tanner, Georgette, Kocakavuk, Emre, Anderson, Kevin J., Abiola, Olajide, Aldape, Kenneth, Alfaro, Kristin D., Alpar, Donat, Amin, Samirkumar B., Ashley, David M., Bandopadhayay, Pratiti, Barnholtz-Sloan, Jill S., Beroukhim, Rameen, Bock, Christoph, Brastianos, Priscilla K., Brat, Daniel J., Brodbelt, Andrew R., Bruns, Alexander F., Bulsara, Ketan R., Chakrabarty, Aruna, Chakravarti, Arnab, Chuang, Jeffrey H., Claus, Elizabeth B., Cochran, Elizabeth J., Connelly, Jennifer, Costello, Joseph F., Finocchiaro, Gaetano, Fletcher, Michael N., French, Pim J., Gan, Hui K., Gilbert, Mark R., Gould, Peter V., Grimmer, Matthew R., Iavarone, Antonio, Ismail, Azzam, Jenkinson, Michael D., Khasraw, Mustafa, Kim, Hoon, Kouwenhoven, Mathilde C.M., LaViolette, Peter S., Li, Meihong, Lichter, Peter, Ligon, Keith L., Lowman, Allison K., Malta, Tathiane M., Mazor, Tali, McDonald, Kerrie L., Molinaro, Annette M., Nam, Do-Hyun, Nayyar, Naema, Ng, Ho Keung, Ngan, Chew Yee, Niclou, Simone, P., Niers, Johanna M., Noushmehr, Houtan, Noorbakhsh, Javad, Ormond, D. Ryan, Park, Chul-Kee, Poisson, Laila M., Rabadan, Raul, Radlwimmer, Bernhard, Rao, Ganesh, Reifenberger, Guido, Sa, Jason K., Schuster, Michael, Shaw, Brian L., Short, Susan C., Sillevis Smitt, Peter A., Sloan, Andrew E., Smits, Marion, Suzuki, Hiromichi, Tabatabai, Ghazaleh, Van Meir, Erwin G., Watts, Colin, Weller, Michael, Wesseling, Pieter, Westerman, Bart A., Widhalm, Georg, Woehrer, Adelheid, Alfred Yung, W.K., Zadeh, Gelareh, Huse, Jason T., de Groot, John F., Stead, Lucy F., Verhaak, Roel G.W.
Publicado 2019