Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition

por Ulanet, Danielle, Jha, Abhishek, Couto, Kiley, Choe, Sung, Wang, Amanda, Woo, Hin-Koon, Steadman, Mya, DeLaBarre, Byron, Gross, Stefan, Driggers, Edward, Dorsch, Marion, Hurov, Jonathan
Publicado 2014

Mesenchymal Phenotype Predisposes Lung Cancer Cells to Impaired Proliferation and Redox Stress in Response to Glutaminase Inhibition

por Ulanet, Danielle B., Couto, Kiley, Jha, Abhishek, Choe, Sung, Wang, Amanda, Woo, Hin-Koon, Steadman, Mya, DeLaBarre, Byron, Gross, Stefan, Driggers, Edward, Dorsch, Marion, Hurov, Jonathan B.
Publicado 2014

The mitochondrial respiratory chain is essential for haematopoietic stem cell function

por Ansó, Elena, Weinberg, Samuel E., Diebold, Lauren P., Thompson, Benjamin J., Malinge, Sébastien, Schumacker, Paul T., Liu, Xin, Zhang, Yuannyu, Shao, Zhen, Steadman, Mya, Marsh, Kelly M., Xu, Jian, Crispino, John D., Chandel, Navdeep S.
Publicado 2017

(13)C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8(+) T cells

por Ma, Eric H., Dahabieh, Michael S., DeCamp, Lisa M., Kaymak, Irem, Kitchen-Goosen, Susan M., Roy, Dominic G., Verway, Mark J., Johnson, Radia M., Samborska, Bozena, Scullion, Catherine A., Steadman, Mya, Vos, Matthew, Roddy, Thomas P., Krawczyk, Connie M., Williams, Kelsey S., Sheldon, Ryan D., Jones, Russell G.
Publicado 2023

JAK2/IDH-mutant–driven myeloproliferative neoplasm is sensitive to combined targeted inhibition

por McKenney, Anna Sophia, Lau, Allison N., Somasundara, Amritha Varshini Hanasoge, Spitzer, Barbara, Intlekofer, Andrew M., Ahn, Jihae, Shank, Kaitlyn, Rapaport, Franck T., Patel, Minal A., Papalexi, Efthymia, Shih, Alan H., Chiu, April, Freinkman, Elizaveta, Akbay, Esra A., Steadman, Mya, Nagaraja, Raj, Yen, Katharine, Teruya-Feldstein, Julie, Wong, Kwok-Kin, Rampal, Raajit, Heiden, Matthew G. Vander, Thompson, Craig B., Levine, Ross L.
Publicado 2018

A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model

por Wang, Fang, Travins, Jeremy, Lin, Zhizhong, Si, Yaguang, Chen, Yue, Powe, Josh, Murray, Stuart, Zhu, Dongwei, Artin, Erin, Gross, Stefan, Santiago, Stephanie, Steadman, Mya, Kernytsky, Andrew, Straley, Kimberly, Lu, Chenming, Pop, Ana, Struys, Eduard A., Jansen, Erwin E. W., Salomons, Gajja S., David, Muriel D., Quivoron, Cyril, Penard-Lacronique, Virginie, Regan, Karen S., Liu, Wei, Dang, Lenny, Yang, Hua, Silverman, Lee, Agresta, Samuel, Dorsch, Marion, Biller, Scott, Yen, Katharine, Cang, Yong, Su, Shin-San Michael, Jin, Shengfang
Publicado 2016