Harnessing soft tissue sarcoma with low-dose pazopanib – a matter of blood levels

por Groenland, Stefanie L., Katz, Daniela, Huitema, Alwin D. R., Steeghs, Neeltje
Publicado 2018

Beta-adrenergic receptor blockade in angiosarcoma: Which beta-blocker to choose?

por Embaby, Alaa, van Merendonk, Lisanne, Steeghs, Neeltje, Beijnen, Jos, Huitema, Alwin
Publicado 2022

A phase 1 open-label study to assess the relative bioavailability of TAK-931 tablets in reference to powder-in-capsule in patients with advanced solid tumors

por Steeghs, Neeltje, Pruis, Melinda, van Herpen, Carla, Lu, Vickie, Redman, John, Zhou, Xiaofei
Publicado 2022

The mutational footprints of cancer therapies

por Pich, Oriol, Muiños, Ferran, Paul Lolkema, Martijn, Steeghs, Neeltje, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Publicado 2019

Framework for Implementing Individualised Dosing of Anti-Cancer Drugs in Routine Care: Overcoming the Logistical Challenges

por van Leuven, Jason, Evans, Simon, Kichenadasse, Ganessan, Steeghs, Neeltje, Bonevski, Billie, Mikus, Gerd, van Dyk, Madelé
Publicado 2023

Clinical Pharmacokinetics and Pharmacodynamics of Pazopanib: Towards Optimized Dosing

por Verheijen, Remy B., Beijnen, Jos H., Schellens, Jan H. M., Huitema, Alwin D. R., Steeghs, Neeltje
Publicado 2017

A Review of CYP3A Drug-Drug Interaction Studies: Practical Guidelines for Patients Using Targeted Oral Anticancer Drugs

por Molenaar-Kuijsten, Laura, Van Balen, Dorieke E. M., Beijnen, Jos H., Steeghs, Neeltje, Huitema, Alwin D. R.
Publicado 2021

Practical Recommendations for Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology

por Verheijen, Remy B., Yu, Huixin, Schellens, Jan H.M., Beijnen, Jos H., Steeghs, Neeltje, Huitema, Alwin D.R.
Publicado 2017

Imatinib, sunitinib and pazopanib: From flat‐fixed dosing towards a pharmacokinetically guided personalized dose

por Westerdijk, Kim, Desar, Ingrid M.E., Steeghs, Neeltje, van der Graaf, Winette T.A., van Erp, Nielka P.
Publicado 2020

Liquid Biopsies in Sarcoma Clinical Practice: Where Do We Stand?

por van der Laan, Pia, van Houdt, Winan J., van den Broek, Daan, Steeghs, Neeltje, van der Graaf, Winette T. A.
Publicado 2021

Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors

por Steeghs, Neeltje, Gelderblom, Hans, Wessels, Judith, Eskens, Ferry A. L. M., de Bont, Natasja, Nortier, Johan W. R., Guchelaar, Henk-Jan
Publicado 2009

Pharmacokinetic Optimization of Everolimus Dosing in Oncology: A Randomized Crossover Trial

por Verheijen, Remy B., Atrafi, Florence, Schellens, Jan H. M., Beijnen, Jos H., Huitema, Alwin D. R., Mathijssen, Ron H. J., Steeghs, Neeltje
Publicado 2017

Determination of the absolute bioavailability of oral imatinib using a stable isotopically labeled intravenous imatinib-d8 microdose

por Roosendaal, Jeroen, Groenland, Stefanie L., Rosing, Hilde, Lucas, Luc, Venekamp, Nikkie, Nuijen, Bastiaan, Huitema, Alwin D. R., Beijnen, Jos H., Steeghs, Neeltje
Publicado 2020

Improved Efficacy of First-Line Imatinib in Advanced Gastrointestinal Stromal Tumors (GIST): The Dutch GIST Registry Data

por Mohammadi, Mahmoud, IJzerman, Nikki S., Hollander, Dide den, Bleckman, Roos F., Oosten, Astrid W., Desar, Ingrid M. E., Reyners, An K. L., Steeghs, Neeltje, Gelderblom, Hans
Publicado 2023

Healthy volunteers in first‐in‐human oncology drug development for small molecules

por de las Heras, Begoña, Bouyoucef‐Cherchalli, Dalila, Reeve, Lesley, Reichl, Andreas, Mandarino, Debra, Flach, Stephen, Vidal, Laura, van Brummelen, Emilie M. J., Steeghs, Neeltje
Publicado 2021

Neoadjuvant Systemic Treatment of Primary Angiosarcoma

por Heinhuis, Kimberley M., IJzerman, Nikki S., van der Graaf, Winette T. A., Kerst, Jan Martijn, Schrage, Yvonne, Beijnen, Jos H., Steeghs, Neeltje, van Houdt, Winan J.
Publicado 2020

Central venous access related adverse events after trabectedin infusions in soft tissue sarcoma patients; experience and management in a nationwide multi-center study

por Verboom, Michiel C., Ouwerkerk, Jan, Steeghs, Neeltje, Lutjeboer, Jacob, Martijn Kerst, J., van der Graaf, Winette T. A., Reyners, Anna K. L., Sleijfer, Stefan, Gelderblom, Hans
Publicado 2017

Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology

por van der Kleij, Maud B. A., Guchelaar, Niels A. D., Mathijssen, Ron H. J., Versluis, Jurjen, Huitema, Alwin D. R., Koolen, Stijn L. W., Steeghs, Neeltje
Publicado 2023

Long-term safety and anti-tumour activity of olaparib monotherapy after combination with carboplatin and paclitaxel in patients with advanced breast, ovarian or fallopian tube canc...

por van der Noll, Ruud, Marchetti, Serena, Steeghs, Neeltje, Beijnen, Jos H, Mergui-Roelvink, Marja W J, Harms, Emmy, Rehorst, Harriet, Sonke, Gabe S, Schellens, Jan H M
Publicado 2015

Survival and Cost-Effectiveness of Trabectedin Compared to Ifosfamide Monotherapy in Advanced Soft Tissue Sarcoma Patients

por Verboom, Michiel C., Gelderblom, Hans, Kerst, J. Martijn, Steeghs, Neeltje, Reyners, Anna K. L., Sleijfer, Stefan, van der Graaf, Winette T. A., van den Hout, Wilbert B.
Publicado 2019