The presence of a functional t-tubule network increases the sensitivity of RyR1 to agonists in skinned rat skeletal muscle fibres

por Duke, Adrian M., Steele, Derek S.
Publicado 2008

DHPR activation underlies SR Ca(2+) release induced by osmotic stress in isolated rat skeletal muscle fibers

por Pickering, James D., White, Ed, Duke, Adrian M., Steele, Derek S.
Publicado 2009

Deterministic and Stochastic Cellular Mechanisms Contributing to Carbon Monoxide Induced Ventricular Arrhythmias

por Al-Owais, Moza M., Steele, Derek S., Holden, Arun V., Benson, Alan P.
Publicado 2021

Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease

por Hurley, Miriam E., White, Ed, Sheard, Thomas M. D., Steele, Derek, Jayasinghe, Izzy
Publicado 2023

TNF-α and IL-1β increase Ca(2+) leak from the sarcoplasmic reticulum and susceptibility to arrhythmia in rat ventricular myocytes

por Duncan, David J., Yang, Zhaokang, Hopkins, Philip M., Steele, Derek S., Harrison, Simon M.
Publicado 2010

Energy Metabolism in the Failing Right Ventricle: Limitations of Oxygen Delivery and the Creatine Kinase System

por Fowler, Ewan D., Hauton, David, Boyle, John, Egginton, Stuart, Steele, Derek S., White, Ed
Publicado 2019

Imatinib Mesylate Induces Necroptotic Cell Death and Impairs Autophagic Flux in Human Cardiac Progenitor Cells

por Walmsley, Robert, Steele, Derek S., Ellison-Hughes, Georgina M., Papaspyros, Sotiris, Smith, Andrew J.
Publicado 2022

Action potential responses to changes in stimulation frequency and isoproterenol in rat ventricular myocytes

por Howlett, Luke A., Kirton, Hannah M., Al‐Owais, Moza M., Steele, Derek, Lancaster, Matthew K.
Publicado 2022

Flecainide induces a sustained countercurrent dependent effect on RyR2 in permeabilized WT ventricular myocytes but not in intact cells

por Steer, Emma J., Yang, Zhaokang, Al-Owais, Moza M., Kirton, Hannah M., White, Edward, Steele, Derek S.
Publicado 2023

Epac2-Rap1 Signaling Regulates Reactive Oxygen Species Production and Susceptibility to Cardiac Arrhythmias

por Yang, Zhaokang, Kirton, Hannah M., Al-Owais, Moza, Thireau, Jérôme, Richard, Sylvain, Peers, Chris, Steele, Derek S.
Publicado 2017

Vascular Kv7 channels control intracellular Ca(2+) dynamics in smooth muscle

por Tsai, Yuan-Ming, Jones, Frederick, Mullen, Pierce, Porter, Karen E., Steele, Derek, Peers, Chris, Gamper, Nikita
Publicado 2020

Inhibition of the Cardiac Na(+) Channel Nav1.5 by Carbon Monoxide

por Elies, Jacobo, Dallas, Mark L., Boyle, John P., Scragg, Jason L., Duke, Adrian, Steele, Derek S., Peers, Chris
Publicado 2014

Inhibition of the voltage-gated potassium channel Kv1.5 by hydrogen sulfide attenuates remodeling through S-nitrosylation-mediated signaling

por Al-Owais, Moza M., Hettiarachchi, Nishani T., Dallas, Mark L., Scragg, Jason L., Lippiat, Jonathan D., Holden, Arun V., Steele, Derek S., Peers, Chris
Publicado 2023

A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K(+) channels in carbon monoxide–induced proarrhythmic early afterdepolarizations

por Al-Owais, Moza M., Hettiarachchi, Nishani T., Kirton, Hannah M., Hardy, Matthew E., Boyle, John P., Scragg, Jason L., Steele, Derek S., Peers, Chris
Publicado 2017

Beta1-adrenoceptor antagonist, metoprolol attenuates cardiac myocyte Ca(2+) handling dysfunction in rats with pulmonary artery hypertension

por Fowler, Ewan D., Drinkhill, Mark J., Norman, Ruth, Pervolaraki, Eleftheria, Stones, Rachel, Steer, Emma, Benoist, David, Steele, Derek S., Calaghan, Sarah C., White, Ed
Publicado 2018

Decreased creatine kinase is linked to diastolic dysfunction in rats with right heart failure induced by pulmonary artery hypertension

por Fowler, Ewan D., Benoist, David, Drinkhill, Mark J., Stones, Rachel, Helmes, Michiel, Wüst, Rob C.I., Stienen, Ger J.M., Steele, Derek S., White, Ed
Publicado 2015

Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K(+) channel Kv1.5

por Al-Owais, Moza M, Hettiarachchi, Nishani T, Boyle, John P, Scragg, Jason L, Elies, Jacobo, Dallas, Mark L, Lippiat, Jon D, Steele, Derek S, Peers, Chris
Publicado 2017

A Mechanism for Statin-Induced Susceptibility to Myopathy

por Lotteau, Sabine, Ivarsson, Niklas, Yang, Zhaokang, Restagno, Damien, Colyer, John, Hopkins, Philip, Weightman, Andrew, Himori, Koichi, Yamada, Takashi, Bruton, Joseph, Steele, Derek, Westerblad, Håkan, Calaghan, Sarah
Publicado 2019

Hydrogen sulfide regulates hippocampal neuron excitability via S-sulfhydration of Kv2.1

por Dallas, Mark L., Al-Owais, Moza M., Hettiarachchi, Nishani T., Vandiver, Matthew Scott, Jarosz-Griffiths, Heledd H., Scragg, Jason L., Boyle, John P., Steele, Derek, Peers, Chris
Publicado 2021

Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform

por Venturi, Elisa, Lindsay, Chris, Lotteau, Sabine, Yang, Zhaokang, Steer, Emma, Witschas, Katja, Wilson, Abigail D, Wickens, James R, Russell, Angela J, Steele, Derek, Calaghan, Sarah, Sitsapesan, Rebecca
Publicado 2018