Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer

por Chakrabarti, Jayati, Holokai, Loryn, Syu, LiJyun, Steele, Nina G., Chang, Julie, Wang, Jiang, Ahmed, Syed, Dlugosz, Andrzej, Zavros, Yana
Publicado 2018

An Organoid-Based Preclinical Model of Human Gastric Cancer

por Steele, Nina G., Chakrabarti, Jayati, Wang, Jiang, Biesiada, Jacek, Holokai, Loryn, Chang, Julie, Nowacki, Lauren M., Hawkins, Jennifer, Mahe, Maxime, Sundaram, Nambirajan, Shroyer, Noah, Medvedovic, Mario, Helmrath, Michael, Ahmad, Syed, Zavros, Yana
Publicado 2018

The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice

por Hoffman, Megan T., Kemp, Samantha B., Salas-Escabillas, Daniel J., Zhang, Yaqing, Steele, Nina G., The, Stephanie, Long, Daniel, Benitz, Simone, Yan, Wei, Margolskee, Robert F., Bednar, Filip, Pasca di Magliano, Marina, Wen, Hui-Ju, Crawford, Howard C.
Publicado 2020

Notch signaling regulates immunosuppressive tumor-associated macrophage function in pancreatic cancer

por Yan, Wei, Steele, Nina G., Kemp, Samantha B., Menjivar, Rosa E., Du, Wenting, Carpenter, Eileen S., Donahue, Katelyn L., Brown, Kristee L., Irizarry-Negron, Valerie, Yang, Sion, Burns, William R., Zhang, Yaqing, di Magliano, Marina Pasca, Bednar, Filip
Publicado 2023

Lorazepam Stimulates IL6 Production and Is Associated with Poor Survival Outcomes in Pancreatic Cancer

por Cornwell, Abigail C., Tisdale, Arwen A., Venkat, Swati, Maraszek, Kathryn E., Alahmari, Abdulrahman A., George, Anthony, Attwood, Kristopher, George, Madison, Rempinski, Donald, Franco-Barraza, Janusz, Seshadri, Mukund, Parker, Mark D., Cortes Gomez, Eduardo, Fountzilas, Christos, Cukierman, Edna, Steele, Nina G., Feigin, Michael E.
Publicado 2023

Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB–Mediated Production of CXCL1

por Kemp, Samantha B., Carpenter, Eileen S., Steele, Nina G., Donahue, Katelyn L., Nwosu, Zeribe C., Pacheco, Amanda, Velez-Delgado, Ashley, Menjivar, Rosa E., Lima, Fatima, The, Stephanie, Espinoza, Carlos E., Brown, Kristee, Long, Daniel, Lyssiotis, Costas A., Rao, Arvind, Zhang, Yaqing, Pasca di Magliano, Marina, Crawford, Howard C.
Publicado 2021

Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer

por Scales, Michael K., Velez-Delgado, Ashley, Steele, Nina G., Schrader, Hannah E., Stabnick, Anna M., Yan, Wei, Mercado Soto, Nayanna M., Nwosu, Zeribe C., Johnson, Craig, Zhang, Yaqing, Salas-Escabillas, Daniel J., Menjivar, Rosa E., Maurer, H. Carlo, Crawford, Howard C., Bednar, Filip, Olive, Kenneth P., Pasca di Magliano, Marina, Allen, Benjamin L.
Publicado 2022

Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages

por Kemp, Samantha B, Steele, Nina G, Carpenter, Eileen S, Donahue, Katelyn L, Bushnell, Grace G, Morris, Aaron H, The, Stephanie, Orbach, Sophia M, Sirihorachai, Veerin R, Nwosu, Zeribe C, Espinoza, Carlos, Lima, Fatima, Brown, Kristee, Girgis, Alexander A, Gunchick, Valerie, Zhang, Yaqing, Lyssiotis, Costas A, Frankel, Timothy L, Bednar, Filip, Rao, Arvind, Sahai, Vaibhav, Shea, Lonnie D, Crawford, Howard C, Pasca di Magliano, Marina
Publicado 2021

Extrinsic KRAS Signaling Shapes the Pancreatic Microenvironment Through Fibroblast Reprogramming

por Velez-Delgado, Ashley, Donahue, Katelyn L., Brown, Kristee L., Du, Wenting, Irizarry-Negron, Valerie, Menjivar, Rosa E., Lasse Opsahl, Emily L., Steele, Nina G., The, Stephanie, Lazarus, Jenny, Sirihorachai, Veerin R., Yan, Wei, Kemp, Samantha B., Kerk, Samuel A., Bollampally, Murali, Yang, Sion, Scales, Michael K., Avritt, Faith R., Lima, Fatima, Lyssiotis, Costas A., Rao, Arvind, Crawford, Howard C., Bednar, Filip, Frankel, Timothy L., Allen, Benjamin L., Zhang, Yaqing, Pasca di Magliano, Marina
Publicado 2022

Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context

por Kerk, Samuel A, Lin, Lin, Myers, Amy L, Sutton, Damien J, Andren, Anthony, Sajjakulnukit, Peter, Zhang, Li, Zhang, Yaqing, Jiménez, Jennifer A, Nelson, Barbara S, Chen, Brandon, Robinson, Anthony, Thurston, Galloway, Kemp, Samantha B, Steele, Nina G, Hoffman, Megan T, Wen, Hui-Ju, Long, Daniel, Ackenhusen, Sarah E, Ramos, Johanna, Gao, Xiaohua, Nwosu, Zeribe C, Galban, Stefanie, Halbrook, Christopher J, Lombard, David B, Piwnica-Worms, David R, Ying, Haoqiang, Pasca di Magliano, Marina, Crawford, Howard C, Shah, Yatrik M, Lyssiotis, Costas A
Publicado 2022

Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells

por Halbrook, Christopher J., Thurston, Galloway, Boyer, Seth, Anaraki, Cecily, Jiménez, Jennifer A., McCarthy, Amy, Steele, Nina G., Kerk, Samuel A., Hong, Hanna S., Lin, Lin, Law, Fiona V., Felton, Catherine, Scipioni, Lorenzo, Sajjakulnukit, Peter, Andren, Anthony, Beutel, Alica K., Singh, Rima, Nelson, Barbara S., Van Den Bergh, Fran, Krall, Abigail S., Mullen, Peter J., Zhang, Li, Batra, Sandeep, Morton, Jennifer P., Stanger, Ben Z., Christofk, Heather R., Digman, Michelle A., Beard, Daniel A., Viale, Andrea, Zhang, Ji, Crawford, Howard C., Pasca di Magliano, Marina, Jorgensen, Claus, Lyssiotis, Costas A.
Publicado 2022