Targeting Csnk1a1 in leukemia

por Stegmaier, Kimberly
Publicado 2014

New Approaches to Target T-ALL

por Roti, Giovanni, Stegmaier, Kimberly
Publicado 2014

Targeting DUBs to degrade oncogenic proteins

por Cremer, Anjali, Stegmaier, Kimberly
Publicado 2020

P410: COMBINING MENIN AND MEK INHIBITION TO TREAT CHILDREN WITH POOR PROGNOSTIC KMT2A-R RAS-MUTANT ACUTE LEUKEMIA

por Scheidegger, Nastassja, Alexe, Gabriela, Khalid, Delan, Perry, Jennifer, Armstrong, Scott, Pikman, Yana, Stegmaier, Kimberly
Publicado 2023

A method for high-throughput gene expression signature analysis

por Peck, David, Crawford, Emily D, Ross, Kenneth N, Stegmaier, Kimberly, Golub, Todd R, Lamb, Justin
Publicado 2006

SYK Regulates mTOR Signaling in AML

por Carnevale, Julia, Ross, Linda, Puissant, Alexandre, Banerji, Versha, Stone, Richard M., DeAngelo, Daniel J., Ross, Kenneth N., Stegmaier, Kimberly
Publicado 2013

High-throughput gene expression profiling of memory differentiation in primary human T cells

por Haining, W Nicholas, Angelosanto, Jill, Brosnahan, Kathleen, Ross, Kenneth, Hahn, Cynthia, Russell, Kate, Drury, Linda, Norton, Stephanie, Nadler, Lee, Stegmaier, Kimberly
Publicado 2008

RAD21 is a driver of chromosome 8 gain in Ewing sarcoma to mitigate replication stress

por Su, Xiaofeng A., Ma, Duanduan, Parsons, James V., Replogle, John M., Amatruda, James F., Whittaker, Charles A., Stegmaier, Kimberly, Amon, Angelika
Publicado 2021

Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia

por Larrue, Clement, Mouche, Sarah, Lin, Shan, Simonetta, Federico, Scheidegger, Nastassja K., Poulain, Laury, Birsen, Rudy, Sarry, Jean-Emmanuel, Stegmaier, Kimberly, Tamburini, Jerome
Publicado 2023

DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia

por Sexauer, Amy N., Alexe, Gabriela, Gustafsson, Karin, Zanetakos, Elizabeth, Milosevic, Jelena, Ayres, Mary, Gandhi, Varsha, Pikman, Yana, Stegmaier, Kimberly, Sykes, David B.
Publicado 2023

Signature-Based Small Molecule Screening Identifies Cytosine Arabinoside as an EWS/FLI Modulator in Ewing Sarcoma

por Stegmaier, Kimberly, Wong, Jenny S, Ross, Kenneth N, Chow, Kwan T, Peck, David, Wright, Renee D, Lessnick, Stephen L, Kung, Andrew L, Golub, Todd R
Publicado 2007

Increased SYK activity is associated with unfavorable outcome among patients with acute myeloid leukemia

por Boros, Katalin, Puissant, Alexandre, Back, Morgan, Alexe, Gabriela, Bassil, Christopher F., Sinha, Papiya, Tholouli, Eleni, Stegmaier, Kimberly, Byers, Richard J., Rodig, Scott J.
Publicado 2015

Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma

por Kennedy, Alyssa L., Vallurupalli, Mounica, Chen, Liying, Crompton, Brian, Cowley, Glenn, Vazquez, Francisca, Weir, Barbara A., Tsherniak, Aviad, Parasuraman, Sudha, Kim, Sunkyu, Alexe, Gabriela, Stegmaier, Kimberly
Publicado 2015

Leukemia-specific delivery of mutant NOTCH1 targeted therapy

por Roti, Giovanni, Qi, Jun, Kitara, Samuel, Sanchez-Martin, Marta, Saur Conway, Amy, Varca, Anthony C., Su, Angela, Wu, Lei, Kung, Andrew L., Ferrando, Adolfo A., Bradner, James E., Stegmaier, Kimberly
Publicado 2018

KLF5 controls glutathione metabolism to suppress p190-BCR-ABL+ B-cell lymphoblastic leukemia

por Zhang, Cuiping, D'Alessandro, Angelo, Wellendorf, Ashley M., Mohmoud, Fatima, Serrano-Lopez, Juana, Perentesis, John P., Komurov, Kakajan, Alexe, Gabriela, Stegmaier, Kimberly, Whitsett, Jeffrey A., Grimes, H. Leighton, Cancelas, Jose A.
Publicado 2018

EWS–FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex

por Selvanathan, Saravana P, Graham, Garrett T, Grego, Alexander R, Baker, Tabari M, Hogg, J Robert, Simpson, Mark, Batish, Mona, Crompton, Brian, Stegmaier, Kimberly, Tomazou, Eleni M, Kovar, Heinrich, Üren, Aykut, Toretsky, Jeffrey A
Publicado 2019

Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma

por Tokarsky, E. John, Crow, Jesse C., Guenther, Lillian M., Sherman, John, Taslim, Cenny, Alexe, Gabriela, Pishas, Kathleen I., Rask, Galen, Justis, Blake S., Kasumova, Ana, Stegmaier, Kimberly, Lessnick, Stephen L., Theisen, Emily R.
Publicado 2022

Rapid-kinetics degron benchmarking reveals off-target activities and mixed agonism-antagonism of MYB inhibitors

por Harada, Taku, Perez, Monika W., Kalfon, Jérémie, Braes, Flora Dievenich, Batley, Rashad, Eagle, Kenneth, Nabet, Behnam, Leifer, Becky, Kruell, Jasmin, Paralkar, Vikram R., Stegmaier, Kimberly, Koehler, Angela N., Orkin, Stuart H., Pimkin, Maxim
Publicado 2023

Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

por Nabet, Behnam, Ferguson, Fleur M., Seong, Bo Kyung A., Kuljanin, Miljan, Leggett, Alan L., Mohardt, Mikaela L., Robichaud, Amanda, Conway, Amy S., Buckley, Dennis L., Mancias, Joseph D., Bradner, James E., Stegmaier, Kimberly, Gray, Nathanael S.
Publicado 2020

Molecular rationale for the use of PI3K/AKT/mTOR pathway inhibitors in combination with crizotinib in ALK-mutated neuroblastoma

por Moore, Nathan F., Azarova, Anna M., Bhatnagar, Namrata, Ross, Kenneth N., Drake, Lauren E., Frumm, Stacey, Liu, Qinsong S., Christie, Amanda L., Sanda, Takaomi, Chesler, Louis, Kung, Andrew L., Gray, Nathanael S., Stegmaier, Kimberly, George, Rani E.
Publicado 2014