Evolution of the eukaryotic protein kinases as dynamic molecular switches

por Taylor, Susan S., Keshwani, Malik M., Steichen, Jon M., Kornev, Alexandr P.
Publicado 2012

Structural Basis for the Regulation of Protein Kinase A by Activation Loop Phosphorylation

por Steichen, Jon M., Kuchinskas, Michael, Keshwani, Malik M., Yang, Jie, Adams, Joseph A., Taylor, Susan S.
Publicado 2012

Global Consequences of Activation Loop Phosphorylation on Protein Kinase A

por Steichen, Jon M., Iyer, Ganesh H., Li, Sheng, Saldanha, S. Adrian, Deal, Michael S., Woods, Virgil L., Taylor, Susan S.
Publicado 2010

One‐step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock‐in mice

por Lin, Ying‐Cing, Pecetta, Simone, Steichen, Jon M, Kratochvil, Sven, Melzi, Eleonora, Arnold, Johan, Dougan, Stephanie K, Wu, Lin, Kirsch, Kathrin H, Nair, Usha, Schief, William R, Batista, Facundo D
Publicado 2018

Optimization of an alum-anchored clinical HIV vaccine candidate

por Rodrigues, Kristen A., Cottrell, Christopher A., Steichen, Jon M., Groschel, Bettina, Abraham, Wuhbet, Suh, Heikyung, Agarwal, Yash, Ni, Kaiyuan, Chang, Jason Y. H., Yousefpour, Parisa, Melo, Mariane B., Schief, William R., Irvine, Darrell J.
Publicado 2023

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

por Kulp, Daniel W., Steichen, Jon M., Pauthner, Matthias, Hu, Xiaozhen, Schiffner, Torben, Liguori, Alessia, Cottrell, Christopher A., Havenar-Daughton, Colin, Ozorowski, Gabriel, Georgeson, Erik, Kalyuzhniy, Oleksandr, Willis, Jordan R., Kubitz, Michael, Adachi, Yumiko, Reiss, Samantha M., Shin, Mia, de Val, Natalia, Ward, Andrew B., Crotty, Shane, Burton, Dennis R., Schief, William R.
Publicado 2017

Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice

por Melzi, Eleonora, Willis, Jordan R., Ma, Krystal M., Lin, Ying-Cing, Kratochvil, Sven, Berndsen, Zachary T., Landais, Elise A., Kalyuzhniy, Oleksandr, Nair, Usha, Warner, John, Steichen, Jon M., Kalyuzhniy, Anton, Le, Amber, Pecetta, Simone, Perez, Manfredo, Kirsch, Kathrin, Weldon, Stephanie R., Falcone, Samantha, Himansu, Sunny, Carfi, Andrea, Sok, Devin, Ward, Andrew B., Schief, William R., Batista, Facundo D.
Publicado 2022

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

por Steichen, Jon M., Kulp, Daniel W., Tokatlian, Talar, Escolano, Amelia, Dosenovic, Pia, Stanfield, Robyn L., McCoy, Laura E., Ozorowski, Gabriel, Hu, Xiaozhen, Kalyuzhniy, Oleksandr, Briney, Bryan, Schiffner, Torben, Garces, Fernando, Freund, Natalia T., Gitlin, Alexander D., Menis, Sergey, Georgeson, Erik, Kubitz, Michael, Adachi, Yumiko, Jones, Meaghan, Mutafyan, Andrew A., Yun, Dong Soo, Mayer, Christian T., Ward, Andrew B., Burton, Dennis R., Wilson, Ian A., Irvine, Darrell J., Nussenzweig, Michel C., Schief, William R.
Publicado 2016

Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses

por Tas, Jeroen M.J., Koo, Ja-Hyun, Lin, Ying-Cing, Xie, Zhenfei, Steichen, Jon M., Jackson, Abigail M., Hauser, Blake M., Wang, Xuesong, Cottrell, Christopher A., Torres, Jonathan L., Warner, John E., Kirsch, Kathrin H., Weldon, Stephanie R., Groschel, Bettina, Nogal, Bartek, Ozorowski, Gabriel, Bangaru, Sandhya, Phelps, Nicole, Adachi, Yumiko, Eskandarzadeh, Saman, Kubitz, Michael, Burton, Dennis R., Lingwood, Daniel, Schmidt, Aaron G., Nair, Usha, Ward, Andrew B., Schief, William R., Batista, Facundo D.
Publicado 2022

Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors

por Willis, Jordan R., Berndsen, Zachary T., Ma, Krystal M., Steichen, Jon M., Schiffner, Torben, Landais, Elise, Liguori, Alessia, Kalyuzhniy, Oleksandr, Allen, Joel D., Baboo, Sabyasachi, Omorodion, Oluwarotimi, Diedrich, Jolene K., Hu, Xiaozhen, Georgeson, Erik, Phelps, Nicole, Eskandarzadeh, Saman, Groschel, Bettina, Kubitz, Michael, Adachi, Yumiko, Mullin, Tina-Marie, Alavi, Nushin B., Falcone, Samantha, Himansu, Sunny, Carfi, Andrea, Wilson, Ian A., Yates, John R., Paulson, James C., Crispin, Max, Ward, Andrew B., Schief, William R.
Publicado 2022

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

por Pauthner, Matthias, Havenar-Daughton, Colin, Sok, Devin, Nkolola, Joseph P., Bastidas, Raiza, Boopathy, Archana V., Carnathan, Diane G., Chandrashekar, Abishek, Cirelli, Kimberly M., Cottrell, Christopher A., Eroshkin, Alexey M., Guenaga, Javier, Kaushik, Kirti, Kulp, Daniel W., Liu, Jinyan, McCoy, Laura E., Oom, Aaron L., Ozorowski, Gabriel, Post, Kai W., Sharma, Shailendra K., Steichen, Jon M., de Taeye, Steven W., Tokatlian, Talar, Torrents de la Peña, Alba, Butera, Salvatore T., LaBranche, Celia C., Montefiori, David C., Silvestri, Guido, Wilson, Ian A., Irvine, Darrell J., Sanders, Rogier W., Schief, William R., Ward, Andrew B., Wyatt, Richard T., Barouch, Dan H., Crotty, Shane, Burton, Dennis R.
Publicado 2017